Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jens Bunt"'
Autor:
Zachary H. Houston, Jens Bunt, Kok-Siong Chen, Simon Puttick, Christopher B. Howard, Nicholas L. Fletcher, Adrian V. Fuchs, Jiwei Cui, Yi Ju, Gary Cowin, Xin Song, Andrew W. Boyd, Stephen M. Mahler, Linda J. Richards, Frank Caruso, Kristofer J. Thurecht
Publikováno v:
ACS Central Science, Vol 6, Iss 5, Pp 727-738 (2020)
Externí odkaz:
https://doaj.org/article/3fb1a902064e45d0828820d915363b4e
Autor:
Laura Morcom, Timothy J Edwards, Eric Rider, Dorothy Jones-Davis, Jonathan WC Lim, Kok-Siong Chen, Ryan J Dean, Jens Bunt, Yunan Ye, Ilan Gobius, Rodrigo Suárez, Simone Mandelstam, Elliott H Sherr, Linda J Richards
Publikováno v:
eLife, Vol 10 (2021)
Corpus callosum dysgenesis (CCD) is a congenital disorder that incorporates either partial or complete absence of the largest cerebral commissure. Remodelling of the interhemispheric fissure (IHF) provides a substrate for callosal axons to cross betw
Externí odkaz:
https://doaj.org/article/a0f288c043a6456c9f5d9a9386ffe164
Autor:
Kristian W. Pajtler, Yiju Wei, Konstantin Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zhang, Sebastian Brabetz, Laura Sieber, Melissa Gulley, Monika Mauermann, Tatjana Wedig, Norman Mack, Yuka Imamura Kawasawa, Tanvi Sharma, Marc Zuckermann, Felipe Andreiuolo, Eric Holland, Kendra Maass, Huiqin Körkel-Qu, Hai-Kun Liu, Felix Sahm, David Capper, Jens Bunt, Linda J. Richards, David T. W. Jones, Andrey Korshunov, Lukas Chavez, Peter Lichter, Mikio Hoshino, Stefan M. Pfister, Marcel Kool, Wei Li, Daisuke Kawauchi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The molecular mechanisms driving proliferation in the pediatric brain cancer epdendymoma are poorly understood. Here the authors show that a YAP1- MAMLD1 fusion drives tumor formation in mice and show that the fusion protein can collaborate with the
Externí odkaz:
https://doaj.org/article/adf1b461d84d45cc809ee416ce32b241
Autor:
Timothy J. Edwards, Laura R. Fenlon, Ryan J. Dean, Jens Bunt, Elliott H. Sherr, Linda J. Richards
Publikováno v:
NeuroImage, Vol 217, Iss , Pp 116868- (2020)
Corpus callosum dysgenesis (CCD) describes a collection of brain malformations in which the main fiber tract connecting the two hemispheres is either absent (complete CCD, or ‘agenesis of the corpus callosum’) or reduced in size (partial CCD). Hu
Externí odkaz:
https://doaj.org/article/3e280126f73b4857b20e1cb9e0f66377
Autor:
Ilan Gobius, Laura Morcom, Rodrigo Suárez, Jens Bunt, Polina Bukshpun, William Reardon, William B. Dobyns, John L.R. Rubenstein, A. James Barkovich, Elliott H. Sherr, Linda J. Richards
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 735-747 (2016)
The corpus callosum is the major axon tract that connects and integrates neural activity between the two cerebral hemispheres. Although ∼1:4,000 children are born with developmental absence of the corpus callosum, the primary etiology of this condi
Externí odkaz:
https://doaj.org/article/8818c85899d244be9596722d1db7333e
Autor:
Jun Tsuyama, Jens Bunt, Linda J. Richards, Hiroko Iwanari, Yasuhiro Mochizuki, Takao Hamakubo, Takuya Shimazaki, Hideyuki Okano
Publikováno v:
Stem Cell Reports, Vol 5, Iss 3, Pp 365-377 (2015)
Mammalian neural stem/progenitor cells (NSPCs) sequentially generate neurons and glia during CNS development. Here we identified miRNA-153 (miR-153) as a modulator of the temporal regulation of NSPC differentiation. Overexpression (OE) of miR-153 del
Externí odkaz:
https://doaj.org/article/82ecfb805d4f4121b6b0c425bdfe3cad
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26058 (2011)
Both OTX2 and MYC are important oncogenes in medulloblastoma, the most common malignant brain tumor in childhood. Much is known about MYC binding to promoter regions, but OTX2 binding is hardly investigated. We used ChIP-on-chip data to analyze the b
Externí odkaz:
https://doaj.org/article/a4cbb1e778d24016ac1ac9845fec99dd
Autor:
Marcel Kool, Jan Koster, Jens Bunt, Nancy E Hasselt, Arjan Lakeman, Peter van Sluis, Dirk Troost, Netteke Schouten-van Meeteren, Huib N Caron, Jacqueline Cloos, Alan Mrsić, Bauke Ylstra, Wieslawa Grajkowska, Wolfgang Hartmann, Torsten Pietsch, David Ellison, Steven C Clifford, Rogier Versteeg
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3088 (2008)
BackgroundMedulloblastoma is the most common malignant brain tumor in children. Despite recent improvements in cure rates, prediction of disease outcome remains a major challenge and survivors suffer from serious therapy-related side-effects. Recent
Externí odkaz:
https://doaj.org/article/85a9aa46f4a043bb939c4550eb28e806