Výsledky vyhledávání

High-throughput nucleoside phosphate monitoring in mammalian cell fed-batch cultivation using quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Autor: Renato Zenobi, Massimo Morbidelli, Stephan R. Fagerer, Jens Boertz, Marija Ivarsson, Martin Pabst, Tobias Habicher, Robert F. Steinhoff, Thomas K. Villiger, Miroslav Soos, Jasmin Krismer

Publikováno v: Biotechnology Journal. 10:190-198

Current methods for monitoring multiple intracellular metabolite levels in parallel are limited in sample throughput capabilities and analyte selectivity. This article presents a novel high-throughput method based on matrix-assisted laser desorption/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a136937171888ced49390819b29f3620
https://doi.org/10.1002/biot.201400292

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Parallel on-line detection of a methylbismuth species by hyphenated GC/EI-MS/ICP-MS technique as evidence for bismuth methylation by human hepatic cells

Autor: Elke Dopp, Joerg Hippler, Alfred V. Hirner, Jens Boertz, Markus Hollmann

Publikováno v: Metallomics. 2:52-56

Methylation of metal(loid)s by bacteria or even mammals is a well known process that can lead to increased toxicity for humans. Nevertheless, reliable analytical techniques and tools are indispensable in speciation analysis of trace elements, especia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d480916bb6dda2f0adaedaad72623d
https://doi.org/10.1039/b911945k

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Comparison of micro- and nanoscale Fe⁺³-containing (Hematite) particles for their toxicological properties in human lung cells in vitro

Autor: Christof Schulz, Thomas A. J. Kuhlbusch, Hugh J. Byrne, Eik Hoffmann, Eva-Maria Prantl, Jens Boertz, Qamar Rahman, Elke Dopp, Hartmut Wiggers, Roel F. P. Schins, Kunal Bhattacharya, Gerrit M. Alink

Publikováno v: Toxicological sciences 126 (2012) 1
Toxicological sciences, 126(1), 173-182
Articles

The specific properties of nanoscale particles, large surface-to-mass ratios and highly reactive surfaces, have increased their commercial application in many fields. However, the same properties are also important for the interaction and bioaccumula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1979c070ff9e8fba3ad846f401d941
https://pubmed.ncbi.nlm.nih.gov/22262566

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Titanium Dioxide Nanoparticles Induce Oxidative Stress and DNA-Adduct Formation but not DNA-Breakage In Human Lung Cells

Autor: Maria Davoren, Kunal Bhattacharya, Elke Dopp, Roel P. F. Schins, Eik Hoffmann, Jens Boertz

Publikováno v: Articles
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 6, Iss 1, p 17 (2009)

Titanium dioxide (TiO2), also known as titanium (IV) oxide or anatase, is the naturally occurring oxide of titanium. It is also one of the most commercially used form. To date, no parameter has been set for the average ambient air concentration of Ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67af28a964676b63686ce4c733caf63f
https://arrow.tudublin.ie/nanolart/101

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Determination of trimethylbismuth in the human body after ingestion of colloidal bismuth subcitrate

Autor: Joerg Hippler, Albert W. Rettenmeier, Jens Boertz, L. M. Hartmann, Klaus Michalke, Alfred V. Hirner, Roland A. Diaz-Bone, Margareta Sulkowski, Frank Mosel

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 37(2)

Biological methylation and hydride formation of metals and metalloids are ubiquitous environmental processes that can lead to the formation of chemical species with significantly increased mobility and toxicity. Whereas much is known about the intera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959c5bd75f4bce0f9a082a9eb37f0fa8
https://pubmed.ncbi.nlm.nih.gov/18981168

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Role of intestinal microbiota in transformation of bismuth and other metals and metalloids into volatile methyl and hydride derivatives in humans and mice

Autor: Alfred V. Hirner, Jens Boertz, Martina Dorsch, Albert W. Rettenmeier, Klaus Michalke, Philip Dammann, Gero Hilken, Annette Schmidt, Britta Huber, Hans J. Hedrich, Reinhard Hensel, Margareta Sulkowski, Frank Mosel, Jörg Meyer

Publikováno v: Applied and environmental microbiology. 74(10)

The present study shows that feces samples of 14 human volunteers and isolated gut segments of mice (small intestine, cecum, and large intestine) are able to transform metals and metalloids into volatile derivatives ex situ during anaerobic incubatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ec8100957bd6a15a2cb78dac720f0e
https://pubmed.ncbi.nlm.nih.gov/18378667

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