Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jens B. Bosse"'
Autor:
Jens B. Bosse, Wolfram Brune
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2 (2023)
Externí odkaz:
https://doaj.org/article/c1c4dd66da9b4e7d838c2cf32bf6614f
Autor:
Felix J. Flomm, Timothy K. Soh, Carola Schneider, Linda Wedemann, Hannah M. Britt, Konstantinos Thalassinos, Søren Pfitzner, Rudolph Reimer, Kay Grünewald, Jens B. Bosse
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8 (2022)
Human Cytomegalovirus (HCMV) can infect a variety of cell types by using virions of varying glycoprotein compositions. It is still unclear how this diversity is generated, but spatio-temporally separated envelopment and egress pathways might play a r
Externí odkaz:
https://doaj.org/article/ebccca0378a44ceabc7c2203df05ecf3
Autor:
Enrico Caragliano, Stefano Bonazza, Giada Frascaroli, Jiajia Tang, Timothy K. Soh, Kay Grünewald, Jens B. Bosse, Wolfram Brune
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110469- (2022)
Summary: Human cytomegalovirus (HCMV) replicates its DNA genome in specialized replication compartments (RCs) in the host cell nucleus. These membrane-less organelles originate as spherical structures and grow in size over time. However, the mechanis
Externí odkaz:
https://doaj.org/article/19f814b0feb24c2395020321e8b28f80
Autor:
Marco R. Rink, Marisa A. P. Baptista, Felix J. Flomm, Thomas Hennig, Adam W. Whisnant, Natalia Wolf, Jürgen Seibel, Lars Dölken, Jens B. Bosse
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Fluorogenic aptamers are an alternative to established methodology for real-time imaging of RNA transport and dynamics. We developed Broccoli-aptamer concatemers ranging from 4 to 128 substrate-binding site repeats and characterized their behavior fu
Externí odkaz:
https://doaj.org/article/21840b55e9c4416483655d04ba35b5a6
Publikováno v:
Viruses, Vol 14, Iss 5, p 960 (2022)
Recent progress has provided clear evidence that many RNA-viruses form cytoplasmic biomolecular condensates mediated by liquid–liquid phase separation to facilitate their replication. In contrast, seemingly contradictory data exist for herpesviruse
Externí odkaz:
https://doaj.org/article/9fe722d3707f499a8f4f684e68cb9441
Autor:
Ian B. Hogue, Jens B. Bosse, Esteban A. Engel, Julian Scherer, Jiun-Ruey Hu, Tony del Rio, Lynn W. Enquist
Publikováno v:
Viruses, Vol 7, Iss 11, Pp 5933-5961 (2015)
In the nearly two decades since the popularization of green fluorescent protein (GFP), fluorescent protein-based methodologies have revolutionized molecular and cell biology, allowing us to literally see biological processes as never before. Naturall
Externí odkaz:
https://doaj.org/article/449a0e23565a401e90b28ddfad923500
Autor:
Jens B. Bosse, Stina Virding, Stephan Y. Thiberge, Julian Scherer, Harald Wodrich, Zsolt Ruzsics, Ulrich H. Koszinowski, Lynn W. Enquist
Publikováno v:
mBio, Vol 5, Iss 5 (2014)
ABSTRACT A considerable part of the herpesvirus life cycle takes place in the host nucleus. While much progress has been made to understand the molecular processes required for virus replication in the nucleus, much less is known about the temporal a
Externí odkaz:
https://doaj.org/article/9ce4c3c01c6c484aaa388b0500a3b027
Publikováno v:
Molecular Microbiology. 117:1317-1323
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus and the leading cause of congenital disabilities as well as a significant cause of disease in immunocompromised patients. The envelopment and egress of HCMV particles is an essential step of th
Autor:
Timothy K. Soh, Susanne Pfefferle, Stephanie Wurr, Ronald von Possel, Lisa Oestereich, Toni Rieger, Charlotte Uetrecht, Maria Rosenthal, Jens B. Bosse
Publikováno v:
PLOS ONE. 18:e0274065
Downstream analysis of virus-infected cell samples, such as reverse transcription polymerase chain reaction (RT PCR) or mass spectrometry, often needs to be performed at lower biosafety levels than their actual cultivation, and thus the samples requi
Autor:
Søren Pfitzner, Jens B. Bosse, Helga Hofmann-Sieber, Felix Flomm, Rudolph Reimer, Thomas Dobner, Kay Grünewald, Linda E. Franken
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13034
International Journal of Molecular Sciences, Vol 22, Iss 13034, p 13034 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13034
International Journal of Molecular Sciences, Vol 22, Iss 13034, p 13034 (2021)
The human adenovirus type 5 (HAdV5) infects epithelial cells of the upper and lower respiratory tract. The virus causes lysis of infected cells and thus enables spread of progeny virions to neighboring cells for the next round of infection. The mecha