Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Jens Als-Nielsen"'
Autor:
Sergey Kapishnikov, Daniel Grolimund, Gerd Schneider, Eva Pereiro, James G. McNally, Jens Als-Nielsen, Leslie Leiserowitz
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract A key drug target for malaria has been the detoxification pathway of the iron-containing molecule heme, which is the toxic byproduct of hemoglobin digestion. The cornerstone of heme detoxification is its sequestration into hemozoin crystals,
Externí odkaz:
https://doaj.org/article/0985f7d76d7140ed84de25c8f8e8ac97
Autor:
Jens Als-Nielsen
Publikováno v:
Israel Journal of Chemistry. 61:598-607
Publikováno v:
'ChemMedChem ', vol: 16, pages: 1515-1532 (2021)
Kapishnikov, S, Hempelmann, E, Elbaum, M, Als-Nielsen, J & Leiserowitz, L 2021, ' Malaria Pigment Crystals : The Achilles ' Heel of the Malaria Parasite ', ChemMedChem . https://doi.org/10.1002/cmdc.202000895
ChemMedChem 16(10), 1515-1532 (2021). doi:10.1002/cmdc.202000895
Chemmedchem
Kapishnikov, S, Hempelmann, E, Elbaum, M, Als-Nielsen, J & Leiserowitz, L 2021, ' Malaria Pigment Crystals : The Achilles ' Heel of the Malaria Parasite ', ChemMedChem . https://doi.org/10.1002/cmdc.202000895
ChemMedChem 16(10), 1515-1532 (2021). doi:10.1002/cmdc.202000895
Chemmedchem
ChemMedChem 16(10), 1515 - 1532 (2021). doi:10.1002/cmdc.202000895
The biogenic formation of hemozoin crystals, a crucial process in heme detoxification by the malaria parasite, is reviewed as an antimalarial drug target. We first focus on the i
The biogenic formation of hemozoin crystals, a crucial process in heme detoxification by the malaria parasite, is reviewed as an antimalarial drug target. We first focus on the i
Autor:
Trine Staalsø, Leslie Leiserowitz, Ana J. Pérez-Berná, Stephan Werner, Eva Pereiro, Ji-Woong Lee, Yang Yang, Jens Als-Nielsen, Peter Guttmann, Sergey Kapishnikov
Publikováno v:
Microscopy and Microanalysis. 26:3004-3006
Autor:
Eva Pereiro, Daniel Grolimund, Leslie Leiserowitz, Gerd Schneider, James G. McNally, Sergey Kapishnikov, Jens Als-Nielsen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Kapishnikov, S, Grolimund, D, Schneider, G, Pereiro, E, McNally, J G, Als-Nielsen, J & Leiserowitz, L 2017, ' Unraveling heme detoxification in the malaria parasite by in situ correlative X-ray fluorescence microscopy and soft X-ray tomography ', Scientific Reports, vol. 7, 7610 . https://doi.org/10.1038/s41598-017-06650-w
Scientific Reports
Kapishnikov, S, Grolimund, D, Schneider, G, Pereiro, E, McNally, J G, Als-Nielsen, J & Leiserowitz, L 2017, ' Unraveling heme detoxification in the malaria parasite by in situ correlative X-ray fluorescence microscopy and soft X-ray tomography ', Scientific Reports, vol. 7, 7610 . https://doi.org/10.1038/s41598-017-06650-w
Scientific Reports
A key drug target for malaria has been the detoxification pathway of the iron-containing molecule heme, which is the toxic byproduct of hemoglobin digestion. The cornerstone of heme detoxification is its sequestration into hemozoin crystals, but how
Autor:
Peter Walter, Mads R. V. Jørgensen, Sebastian Christensen, Jacob Becker, Bo B. Iversen, Hidetaka Kasai, Kasper Tolborg, Jens Als-Nielsen, Ann-Christin Dippel
Publikováno v:
Tolborg, K, Jørgensen, M R V, Christensen, S, Kasai, H, Becker, J, Walter, P, Dippel, A C, Als-Nielsen, J & Iversen, B B 2017, ' Accurate charge densities from powder X-ray diffraction-a new version of the Aarhus vacuum imaging-plate diffractometer ', Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, vol. 73, no. 4, pp. 521-530 . https://doi.org/10.1107/S2052520617006357
In recent years powder X-ray diffraction has proven to be a valuable alternative to single-crystal X-ray diffraction for determining electron-density distributions in high-symmetry inorganic materials, including subtle deformation in the core electro
Autor:
Eva Pereiro, Sergey Kapishnikov, Leslie Leiserowitz, Jens Als-Nielsen, Yang Yang, Peter Cloetens, F. Awamu Ndonglack, Kai Matuschewski
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7, 9 p. ⟨10.1038/s41598-017-00921-2⟩
'Scientific Reports ', vol: 7, pages: 802-1802-9 (2017)
Recercat. Dipósit de la Recerca de Catalunya
instname
Kapishnikov, S, Leiserowitz, L, Yang, Y, Cloetens, P, Pereiro, E, Ndonglack, F A, Matuschewski, K & Als-Nielsen, J 2017, ' Biochemistry of malaria parasite infected red blood cells by X-ray microscopy ', Scientific Reports, vol. 7, 802 . https://doi.org/10.1038/s41598-017-00921-2
Universitat Autònoma de Barcelona
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7, 9 p. ⟨10.1038/s41598-017-00921-2⟩
'Scientific Reports ', vol: 7, pages: 802-1802-9 (2017)
Recercat. Dipósit de la Recerca de Catalunya
instname
Kapishnikov, S, Leiserowitz, L, Yang, Y, Cloetens, P, Pereiro, E, Ndonglack, F A, Matuschewski, K & Als-Nielsen, J 2017, ' Biochemistry of malaria parasite infected red blood cells by X-ray microscopy ', Scientific Reports, vol. 7, 802 . https://doi.org/10.1038/s41598-017-00921-2
Red blood cells infected by the malaria parasite Plasmodium falciparum are correlatively imaged by tomography using soft X-rays as well as by scanning hard nano-X-ray beam to obtain fluorescence maps of various elements such as S and Fe. In this way
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416750d18e2721522a603b687e8127ba
https://ddd.uab.cat/record/202523
https://ddd.uab.cat/record/202523
Publikováno v:
Straasø, T, Dippel, A-C, Becker, J & Als-Nielsen, J 2014, ' Model-independent structure factors from powder X-ray diffraction : A novel approach ', Journal of Synchrotron Radiation, vol. 21, no. 1, pp. 119-126 . https://doi.org/10.1107/S1600577513028269
Journal of synchrotron radiation 21(1), 119-126 (2014). doi:10.1107/S1600577513028269
Journal of synchrotron radiation 21(1), 119-126 (2014). doi:10.1107/S1600577513028269
Under the experimental condition that all Bragg peaks in a powder X-ray diffraction (PXRD) pattern have the same shape, one can readily obtain the Bragg intensities without fitting any parameters. This condition is fulfilled at the P02.1 beamline at
Publikováno v:
Journal of Applied Crystallography. 46:663-671
A statistical method to determine the background level and separate signal from background in a Poisson-distributed background data set is described. The algorithm eliminates the pixel with the highest intensity value in an iterative manner until the
Publikováno v:
Physical review / B 94(1), 014111 (2016). doi:10.1103/PhysRevB.94.014111
β -brass exhibits an archetypical example of an order-disorder transition with a critical behavior that was previously investigated by neutron scattering. The data were well described by the three-dimensional (3d) Ising model but the relatively crud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8a9827620065e2490f1d05ed7b8962
https://bib-pubdb1.desy.de/record/301385
https://bib-pubdb1.desy.de/record/301385