SILAC-MS Based Characterization of LPS and Resveratrol Induced Changes in Adipocyte Proteomics - Resveratrol as Ameliorating Factor on LPS Induced Changes.

Autor: Mark K Nøhr, Toke P Kroager, Kristian W Sanggaard, Anders D Knudsen, Allan Stensballe, Jan J Enghild, Jens Ølholm, Bjørn Richelsen, Steen B Pedersen

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0159747 (2016)

Adipose tissue inflammation is believed to play a pivotal role in the development obesity-related morbidities such as insulin resistance. However, it is not known how this (low-grade) inflammatory state develops. It has been proposed that the leakage

Externí odkaz: https://doaj.org/article/c421067a3d704037b21c219479ff853b

SILAC-MS Based Characterization of LPS and Resveratrol Induced Changes in Adipocyte Proteomics:Resveratrol as Ameliorating Factor on LPS Induced Changes

Autor: Kristian W. Sanggaard, Steen B. Pedersen, Jens Ølholm, Toke P Kroager, Anders Dahl Knudsen, Jan J. Enghild, Allan Stensballe, Bjørn Richelsen, Mark K. Nøhr

Publikováno v: Nøhr, M K, Kroager, T P, Sanggaard, K W, Knudsen, A D, Stensballe, A, Enghild, J J, Ølholm, J, Richelsen, B & Pedersen, S B 2016, ' SILAC-MS Based Characterization of LPS and Resveratrol Induced Changes in Adipocyte Proteomics : Resveratrol as Ameliorating Factor on LPS Induced Changes ', PLoS ONE, vol. 11, no. 7, e0159747 . https://doi.org/10.1371/journal.pone.0159747
PLoS ONE, Vol 11, Iss 7, p e0159747 (2016)
PLoS ONE
Nøhr, M K, Kroager, T P, Sanggaard, K W, Knudsen, A D, Stensballe, A, Enghild, J J, Larsen, J Ø, Richelsen, B & Pedersen, S B 2016, ' SILAC-MS Based Characterization of LPS and Resveratrol Induced Changes in Adipocyte Proteomics-Resveratrol as Ameliorating Factor on LPS Induced Changes ', PLOS ONE, vol. 11, no. 7, e0159747 . https://doi.org/10.1371/journal.pone.0159747

Adipose tissue inflammation is believed to play a pivotal role in the development obesity-related morbidities such as insulin resistance. However, it is not known how this (low-grade) inflammatory state develops. It has been proposed that the leakage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c367818cb32fe5043483c286e9ca07d
https://vbn.aau.dk/da/publications/f20280c8-1b43-415f-8ec0-b02422db4261

Resveratrol up-regulates hepatic uncoupling protein 2 and prevents development of nonalcoholic fatty liver disease in rats fed a high-fat diet

Autor: Stephen Hamilton-Dutoit, Jens Ølholm Larsen, Bjørn Richelsen, Niels Jessen, Søren K. Paulsen, Morten Poulsen, Steen B. Pedersen, Berthil F. Clasen, Thomas Kjaer

Publikováno v: Poulsen, M M, Larsen, J Ø, Hamilton-Dutoit, S, Clasen, B F, Jessen, N, Paulsen, S K, Kjær, T N, Richelsen, B & Pedersen, S B 2012, ' Resveratrol up-regulates hepatic uncoupling protein 2 and prevents development of nonalcoholic fatty liver disease in rats fed a high-fat diet ', Nutrition Research, vol. 32, no. 9, pp. 701-8 . https://doi.org/10.1016/j.nutres.2012.08.004

Obesity is associated with a markedly increased risk of nonalcoholic fatty liver disease. The anti-inflammatory polyphenol resveratrol possess promising properties in preventing this metabolic condition by dampening the pathological inflammatory reac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86a597b24fb9c102bc24bc853888ee6
https://pubmed.ncbi.nlm.nih.gov/23084643

Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants

Autor: Bjørn Richelsen, S K Paulsen, K B Cullberg, Jens Ølholm, Steen B. Pedersen

Publikováno v: Larsen, J Ø, Paulsen, S K, Cullberg, K B, Richelsen, B & Pedersen, S B 2010, ' Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants ', International Journal of Obesity . https://doi.org/10.1038/ijo.2010.98

Udgivelsesdato: 2010-Jun-8 Objective:Human obesity is closely associated with a state of chronic low-grade inflammation, which also involves the adipose tissue with enhanced production of bioactive substances (adipokines). Calorie restriction (CR) re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34391f4dc0ba1b99033539f424bc6762
https://pure.au.dk/portal/da/publications/antiinflammatory-effect-of-resveratrol-on-adipokine-expression-and-secretion-in-human-adipose-tissue-explants(cfecbbd0-b417-11df-8c1a-000ea68e967b).html

Low Sirt1 expression, which is upregulated by fasting, in human adipose tissue from obese women

Autor: Steen B. Pedersen, Jens Ølholm Larsen, Søren Kildeberg Paulsen, Marianne Faurholt Bennetzen, Bjørn Richelsen

Publikováno v: Pedersen, S B, Larsen, J Ø, Paulsen, S K, Bennetzen, M F & Richelsen, B 2008, ' Low Sirt1 expression, which is upregulated by fasting, in human adipose tissue from obese women. ', International Journal of Obesity, vol. 32, no. 8, pp. 1250-5 .
Aarhus University

Udgivelsesdato: august

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::99f56ebcc2675332ee18773707a1f785
https://pure.au.dk/portal/da/publications/low-sirt1-expression-which-is-upregulated-by-fasting-in-human-adipose-tissue-from-obese-women(61e022e0-6f62-11dd-9251-000ea68e967b).html