Zobrazeno 1 - 10
of 350
pro vyhledávání: '"Jens, Leipziger"'
Autor:
Molly A. Bingham, Kim Neijman, Chin-Rang Yang, Angel Aponte, Angela Mak, Hiroaki Kikuchi, Hyun Jun Jung, Brian G. Poll, Viswanathan Raghuram, Euijung Park, Chung-Lin Chou, Lihe Chen, Jens Leipziger, Mark A. Knepper, Margo Dona
Publikováno v:
Bingham, M A, Neijman, K, Yang, C R, Aponte, A, Mak, A, Kikuchi, H, Jung, H J, Poll, B G, Raghuram, V, Park, E, Chou, C L, Chen, L, Leipziger, J, Knepper, M A & Dona, M 2023, ' Circadian gene expression in mouse renal proximal tubule ', American Journal of Physiology: Renal Physiology, vol. 324, no. 3, pp. F301-F314 . https://doi.org/10.1152/ajprenal.00231.2022
American Journal of Physiology : Renal Physiology, 324, F301-F314
American Journal of Physiology : Renal Physiology, 324, 3, pp. F301-F314
American Journal of Physiology : Renal Physiology, 324, F301-F314
American Journal of Physiology : Renal Physiology, 324, 3, pp. F301-F314
Item does not contain fulltext Circadian variability in kidney function is well recognized but is often ignored as a potential confounding variable in physiological experiments. Here, we have created a data resource consisting of expression levels fo
Autor:
Peder Berg, Mads V. Sorensen, Amalie Quist Rousing, Hanne Vebert Olesen, Søren Jensen-Fangel, Majbritt Jeppesen, Jens Leipziger
Publikováno v:
Berg, P, Sorensen, M V, Rousing, A Q, Olesen, H V, Jensen-Fangel, S, Jeppesen, M & Leipziger, J 2022, ' Challenged Urine Bicarbonate Excretion as a Measure of Cystic Fibrosis Transmembrane Conductance Regulator Function in Cystic Fibrosis ', Annals of Internal Medicine, vol. 175, no. 11, pp. 1543-1551 . https://doi.org/10.7326/M22-1741
BACKGROUND: In cystic fibrosis (CF), renal base excretion is impaired. Accordingly, challenged urine bicarbonate excretion may be an in vivo biomarker of cystic fibrosis transmembrane conductance regulator (CFTR) function.OBJECTIVE: To evaluate the a
Autor:
Nikita Misella Hansen, Peder Berg, Marianne Rix, Manan Pareek, Jens Leipziger, Anne-Lise Kamper, Arne Astrup, Mads Vaarby Sørensen, Louise Salomo
Publikováno v:
Hansen, N M, Berg, P, Rix, M, Pareek, M, Leipziger, J, Kamper, A-L, Astrup, A, Sørensen, M V & Salomo, L 2022, ' The New Nordic Renal Diet induces a pronounced reduction of urine acid excretion and uremic toxins in CKD patients (stage 3 and 4) ', Journal of Renal Nutrition .
Aarhus University
Aarhus University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0b2a661ebb5b2127f17478e14a4e044c
https://pure.au.dk/portal/da/publications/the-new-nordic-renal-diet-induces-a-pronounced-reduction-of-urine-acid-excretion-and-uremic-toxins-in-ckd-patients-stage-3-and-4(02034c0d-96eb-45c1-a991-093bc77459d8).html
https://pure.au.dk/portal/da/publications/the-new-nordic-renal-diet-induces-a-pronounced-reduction-of-urine-acid-excretion-and-uremic-toxins-in-ckd-patients-stage-3-and-4(02034c0d-96eb-45c1-a991-093bc77459d8).html
Autor:
Molly A. Bingham, Kim Neijman, Hiroaki Kikuchi, Hyun Jun Jung, Brian G. Poll, Viswanathan Raghuram, Euijung Park, Chin-Rang Yang, Chung-Lin Chou, Lihe Chen, Jens Leipziger, Mark A. Knepper, Margo Dona
Circadian variability in kidney function has long been recognized but is often ignored as a potential confounding variable in in vivo physiological experiments. To provide a guide for physiological studies on the kidney proximal tubule, we have now c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f2aa574b3bdfa912a8d20c44b82aaa3
https://doi.org/10.1101/2022.08.26.505418
https://doi.org/10.1101/2022.08.26.505418
Autor:
Nikita Misella Hansen, Peder Berg, Marianne Rix, Manan Pareek, Jens Leipziger, Anne-Lise Kamper, Arne Astrup, Mads Vaarby Sorensen, Louise Salomo
Publikováno v:
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.
Metabolic acidosis and the uremic toxins, indoxyl sulfate (IS) and p-cresyl sulfate (PCS), are associated with increased risks of kidney disease progression, muscle catabolism, cardiovascular disease, and mortality in patients with chronic kidney dis
Autor:
Jesper Frank Andersen, Charles S. Wingo, Jens Leipziger, Niklas Ayasse, I. Jeanette Lynch, Natalya U. Fedosova, Samuel L Svendsen, Mads V. Sorensen, Peder Berg
Publikováno v:
Ayasse, N, Berg, P, Andersen, J F, Svendsen, S L S C, Sørensen, M V, Fedosova, N, Wingo, C, Lynch, I J & Leipziger, J G 2021, ' Benzamil-mediated urine alkalization is caused by the inhibition of H +, K + ATPases ', American Journal of Physiology: Renal Physiology, vol. 320, no. 4, pp. F596-F607 . https://doi.org/10.1152/ajprenal.00444.2020
Epithelial Na+ channel (ENaC) blockers elicit acute and substantial increases of urinary pH. The underlying mechanism remains to be understood. Here, we evaluated if benzamil-induced urine alkalization is mediated by an acute reduction in H+ secretio
Autor:
Jeppe Olsen, Vladimir V. Matchkov, Mads V. Sorensen, Ebbe Boedtkjer, Peder Berg, Vibeke Secher Dam, Samuel L Svendsen, Jens Leipziger
Publikováno v:
Olsen, J S, Svendsen, S L S C, Berg, P, Dam, V S, Sørensen, M V, Matchkov, V, Leipziger, J G & Boedtkjer, E 2021, ' NBCn1 increases NH 4 + reabsorption across thick ascending limbs, the capacity for urinary NH 4 + excretion, and early recovery from metabolic acidosis ', Journal of the American Society of Nephrology, vol. 32, no. 4, pp. 852-865 . https://doi.org/10.1681/ASN.2019060613
BACKGROUND: The electroneutral Na +/HCO 3 - cotransporter NBCn1 (Slc4a7) is expressed in basolateral membranes of renal medullary thick ascending limbs (mTALs). However, direct evidence that NBCn1 contributes to acid-base handling in mTALs, urinary n
Publikováno v:
Toxins, Vol 5, Iss 3, Pp 472-487 (2013)
The pore-forming exotoxin α-hemolysin from E. coli causes a significant volume reduction of human erythrocytes that precedes the ultimate swelling and lysis. This shrinkage results from activation of Ca2+-sensitive K+ (KCa3.1) and Cl− channels (TM
Externí odkaz:
https://doaj.org/article/e82f5523ff8f466f8f9e900bcb8b111e
Autor:
Simon D. Roger, Matthew R. Weir, Jolanta Malyszko, Amanda K. Leonberg-Yoo, Sunil Bhandari, Charles S. Wingo, George L. Bakris, Jens Leipziger, Michael Walsh, Brenda R. Hemmelgarn, Morgan E. Grams, Andrew Smyth, David M. Charytan, Manish M. Sood, Johannes F.E. Mann, Wolfgang C. Winkelmayer, David H. Ellison, Lilian Cuppari, Gregor Lindner, Matti Marklund, Oleh Pochynyuk, Csaba P. Kovesdy, Patrick Rossignol, Roberto Pecoits-Filho, Stein Hallan, Emmanuel A. Burdmann, Masahiko Nagahama, Katrina L. Campbell, Meg Jardine, Michael Cheung, Charles A. Herzog, Alicia A. McDonough, David C. Wheeler, Stephan J. L. Bakker, David Goldsmith, Edgar V. Lerma, Gregory A. Kline, Zubaid Rafique, Jiang He, Thyago Proença de Moraes, Ewout J. Hoorn, Bruce M. Robinson, Melanie P. Hoenig, Adam J. Singer, Deborah J. Clegg, Sankar D. Navaneethan, Biff F. Palmer, Catherine M. Clase, Gloria Ashuntantang, Juan Jesus Carrero, Bertram Pitt, Jose Ernesto Lopez-Almaraz, Gregorio T. Obrador
Publikováno v:
Kidney International, 97(1), 42-61. Elsevier Inc.
Potassium disorders are common in patients with kidney disease, particularly in patients with tubular disorders and low glomerular filtration rate. A multidisciplinary group of researchers and clinicians met in October 2018 to identify evidence and a
Autor:
Peder Berg, Jesper Frank Andersen, Mads Vaarby Sørensen, Tobias Wang, Hans Malte, Jens Leipziger
Publikováno v:
Berg, P, Andersen, J F, Sørensen, M V, Wang, T, Malte, H & Leipziger, J 2022, ' Alkalosis-induced hypoventilation in cystic fibrosis : The importance of efficient renal adaptation ', PNAS (Proceedings of the National Academy of Sciences of the United States of America), bind 119, nr. 8, e2116836119 . https://doi.org/10.1073/pnas.2116836119
Significance statement: In conditions when our blood experiences alkalosis, a pronounced kidney response is initiated causing a marked increase of urine base excretion. We recently discovered the cellular physiology of this, which employs fast activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb3e7bdfca09e25ae9f8461001715d8
https://pure.au.dk/portal/da/publications/alkalosisinduced-hypoventilation-in-cystic-fibrosis(d2e6f349-e709-4f46-b036-72aaafc57ae0).html
https://pure.au.dk/portal/da/publications/alkalosisinduced-hypoventilation-in-cystic-fibrosis(d2e6f349-e709-4f46-b036-72aaafc57ae0).html