Zobrazeno 1 - 10
of 313
pro vyhledávání: '"Jens, Kastrup"'
Autor:
Abbas Ali Qayyum, Sabina Frljak, Morten Juhl, Gregor Poglajen, Gregor Zemljičl, Andraz Cerar, Thomas Litman, Annette Ekblond, Mandana Haack‐Sørensen, Lisbeth Drozd Højgaard, Jens Kastrup, Bojan Vrtovec
Publikováno v:
ESC Heart Failure, Vol 11, Iss 6, Pp 3882-3891 (2024)
Abstract Aims Allogeneic stem cell therapy is more logistically suitable compared with autologous cell therapy for large‐scale patient treatment. We aim to investigate the clinical safety and efficacy profile of the allogeneic adipose tissue derive
Externí odkaz:
https://doaj.org/article/4efbc44cf58741399740863e39dcfb5d
Autor:
Jens Kastrup, Anthony Mathur, Francisco Fernández-Avilés, Matthew Kelham, Juhani Knuuti, Daniel A Jones, Seppo Ylä-Herttuala, Antti Saraste, Ricardo Sanz-Ruiz, Aleksi J Leikas, Juha E K Hartikainen, Mariann Gyöngyösi, Wojtek Wojakowski, Adrian Gwizdała, Riho Luite, Marko Nikkinen, Abbas A Qayyum, Mandana Haack-Sørensen, Kevin Hamzaraj, Andreas Spannbauer, Maria E Fernández-Santos, Marek Jędrzejek, Agnieszka Skoczyńska, Niklas Vartiainen
Publikováno v:
Open Heart, Vol 11, Iss 2 (2024)
Background Despite tremendous therapeutic advancements, a significant proportion of coronary artery disease patients suffer from refractory angina pectoris, that is, quality-of-life-compromising angina that is non-manageable with established pharmaco
Externí odkaz:
https://doaj.org/article/568f4e4255744c448364960cbaf7874c
Autor:
Rebekka Harary Søndergaard, Lisbeth Drozd Højgaard, Mandana Haack-Sørensen, Cecilie Hoeeg, Ellen Mønsted Johansen, Bjarke Follin, Jens Kastrup, Annette Ekblond, Morten Juhl
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103417- (2024)
The pro-angiogenic abilities of adipose-derived stromal cells (ASCs) make them attractive candidates for cellular therapy, especially for ischemic disease indications. However, details regarding the underlying mechanisms remain elusive. Therefore, th
Externí odkaz:
https://doaj.org/article/4d899c4caf9d4799bb11d4eedef7e62b
Autor:
Kathrine Kronberg Jakobsen, Amanda-Louise Fenger Carlander, Christian Grønhøj, Tobias Todsen, Jacob Melchiors, Natasja Paaske, Anne Kathrine Østergaard Madsen, Jens Kastrup, Annette Ekblond, Mandana Haack-Sørensen, Mohammad Farhadi, Christian Maare, Jeppe Friborg, Charlotte Duch Lynggard, Christian von Buchwald
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background A predominant side effect of radiotherapy for head and neck cancer is salivary gland hypofunction and xerostomia leading to debilitating oral disorders and impaired quality of life (QoL). Intraglandular mesenchymal stem cell thera
Externí odkaz:
https://doaj.org/article/d70de585fe4441098c4594e35de1f04b
Autor:
Abbas Ali Qayyum, Mette Mouridsen, Brian Nilsson, Ida Gustafsson, Morten Schou, Olav Wendelboe Nielsen, Jens Dahlgaard Hove, Anders Bruun Mathiasen, Erik Jørgensen, Steffen Helqvist, Francis Richard Joshi, Ellen Mønsted Johansen, Bjarke Follin, Morten Juhl, Lisbeth Drozd Højgaard, Mandana Haack‐Sørensen, Annette Ekblond, Jens Kastrup
Publikováno v:
ESC Heart Failure, Vol 10, Iss 2, Pp 1170-1183 (2023)
Abstract Aims Patients suffering from chronic ischaemic heart failure with reduced left ventricular ejection fraction (HFrEF) have reduced quality‐of‐life, repetitive hospital admissions, and reduced life expectancy. Allogeneic cell therapy is cu
Externí odkaz:
https://doaj.org/article/f882d6dad9da43c88abf187c99df80eb
Autor:
Charlotte Duch Lynggaard, Rosa Jersie-Christensen, Morten Juhl, Siri Beier Jensen, Christian Grønhøj, Jacob Melchiors, Søren Jacobsen, Michael Møller-Hansen, Mikkel Herly, Annette Ekblond, Jens Kastrup, Anne Fischer-Nielsen, Daniel Belstrøm, Christian von Buchwald
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-12 (2022)
Lynggaard et al. profile the salivary proteome and metaproteome in patients with head and neck cancer who have received radiation therapy and an intraglandular mesenchymal stem cell (MSC) treatment for radiation-induced xerostomia and in healthy cont
Externí odkaz:
https://doaj.org/article/6dfdb68785ce454eb915038edeb94bf1
Autor:
Rebekka Harary Søndergaard, Lisbeth Drozd Højgaard, Alexander Lynge Reese-Petersen, Cecilie Hoeeg, Anders Bruun Mathiasen, Mandana Haack-Sørensen, Bjarke Follin, Federica Genovese, Jens Kastrup, Morten Juhl, Annette Ekblond
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Adipose-derived stromal cells (ASCs) possess a multitude of regenerative capabilities, which include immunomodulation, angiogenesis, and stimulation of extracellular matrix (ECM) remodeling. However, the underlying mechanisms lead
Externí odkaz:
https://doaj.org/article/04fa9dc192634084b562bfa942d6a9bf
Autor:
Anthony Mathur, Doo Sun Sim, Fizzah Choudry, Jessry Veerapen, Martina Colicchia, Tymoteusz Turlejski, Mohsin Hussain, Stephen Hamshere, Didier Locca, Roby Rakhit, Tom Crake, Jens Kastrup, Samir Agrawal, Daniel A. Jones, John Martin
Publikováno v:
ESC Heart Failure, Vol 9, Iss 2, Pp 1152-1159 (2022)
Abstract Aims The long‐term outcomes of the intracoronary delivery of autologous bone marrow‐derived cells (BMCs) after acute myocardial infarction are not well established. Following the promising 1 year results of the REGENERATE‐AMI trial (de
Externí odkaz:
https://doaj.org/article/cdfc1c122df049d1b1fdcbdf6497c5c7
Autor:
Stine Bangsgaard Hansen, Lisbeth Drozd Højgaard, Jens Kastrup, Annette Ekblond, Bjarke Follin, Morten Juhl
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The expeditious progress of Mesenchymal Stromal Cells (MSC) for therapeutic intervention calls for means to compare differences in potency of cell products. The differences may be attributed to innumerable sources including tissue origin, production
Externí odkaz:
https://doaj.org/article/163acc9cf5f241f6b1bf131f1fd7e7c6
Autor:
Thomas J. Povsic, Ricardo Sanz‐Ruiz, Andreu M. Climent, Roberto Bolli, Doris A. Taylor, Bernard J. Gersh, Philippe Menasché, Emerson C. Perin, Giulio Pompilio, Douwe E. Atsma, Lina Badimon, Anthony N. DeMaria, Joshua M. Hare, Timothy D. Henry, Stefan Janssens, Jens Kastrup, Daniele Torella, Jay H. Traverse, James T. Willerson, Francisco Fernández‐Avilés
Publikováno v:
ESC Heart Failure, Vol 8, Iss 3, Pp 2306-2309 (2021)
Abstract The concept that cell‐based repair of myocardial injury might be possible was introduced almost two decades ago; however, the field of cardiovascular reparative medicine has been criticized as translation to clinically effective approaches
Externí odkaz:
https://doaj.org/article/aa0ac4175dff4a92ac246bdf889ab4ba