Zobrazeno 1 - 10
of 322
pro vyhledávání: '"Jens, Gempt"'
Autor:
Mareike Rutenkröger, Svenja Wandke, Jens Gempt, Lasse Dührsen, Maximilian Scheer, Christian Strauss, Hannah Führes
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-6 (2024)
Abstract Background Vestibular schwannomas (VSs) are benign tumors of the vestibulocochlear nerve that often cause significant neurological and functional impairment. Patient-reported outcomes, including quality of life (QoL), are essential for under
Externí odkaz:
https://doaj.org/article/94414252225a466e8c8eb04579474da4
Autor:
Matthias Preusser, Tomáš Kazda, Emilie Le Rhun, Felix Sahm, Marion Smits, Jens Gempt, Johan AF Koekkoek, Angelo F Monti, Marcell Csanadi, János György Pitter, Helen Bulbek, Beatrice Fournier, Caroline Quoilin, Thierry Gorlia, Michael Weller, Giuseppe Minniti, on behalf of the European Organisation for Research, Treatment of Cancer (EORTC) Brain Tumor Group
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Chemotherapy with lomustine is widely considered as standard treatment option for progressive glioblastoma. The value of adding radiotherapy to second-line chemotherapy is not known. Methods EORTC-2227-BTG (LEGATO, NCT05904119) is
Externí odkaz:
https://doaj.org/article/da487c7b1214453fb930ea4fb6b04a3a
Autor:
Richard Drexler, Florian Brembach, Jennifer Sauvigny, Franz L. Ricklefs, Alicia Eckhardt, Helena Bode, Jens Gempt, Katrin Lamszus, Manfred Westphal, Ulrich Schüller, Malte Mohme
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-8 (2024)
Abstract DNA methylation analysis has become a powerful tool in neuropathology. Although DNA methylation-based classification usually shows high accuracy, certain samples cannot be classified and remain clinically challenging. We aimed to gain insigh
Externí odkaz:
https://doaj.org/article/148f558c75074ac9829fbfc45b1d8605
Autor:
Maria Goldberg, Valeri Heinrich, Ghaith Altawalbeh, Chiara Negwer, Arthur Wagner, Jens Gempt, Bernhard Meyer, Amir Kaywan Aftahy
Publikováno v:
Medicina, Vol 60, Iss 9, p 1464 (2024)
Background and Objectives: The impact of surgery for recurrent brain metastases in elderly patients has been the object of debate due to limited information in the literature. We analyzed clinical outcome and survival of elderly patients with recurre
Externí odkaz:
https://doaj.org/article/43d3a261b82947449952068d7fc2f3f9
Autor:
Ghaith Altawalbeh, Maria Goldberg, Michel Gustavo Mondragón-Soto, Chiara Negwer, Arthur Wagner, Jens Gempt, Bernhard Meyer, Amir Kaywan Aftahy
Publikováno v:
Cancers, Vol 16, Iss 16, p 2774 (2024)
Intraoperative magnetic resonance imaging (iMRI) has witnessed significant growth in the field of neurosurgery, particularly in glioma surgery, enhancing image-guided neuronavigation and optimizing the extent of resection (EOR). Despite its extensive
Externí odkaz:
https://doaj.org/article/be8acc3f20764cab851690cb63e61f7c
Single brain metastases – prognostic factors and impact of residual tumor burden on overall survival
Autor:
Lea Baumgart, Aida Anetsberger, Amir Kaywan Aftahy, Benedikt Wiestler, Denise Bernhardt, Stephanie E. Combs, Hanno S. Meyer, Gerhard Schneider, Bernhard Meyer, Jens Gempt
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundBrain metastases (BM) are a common and challenging issue, with their incidence on the rise due to advancements in systemic therapies and increased patient survival. Most patients present with single BM, some of them without any further extr
Externí odkaz:
https://doaj.org/article/14666efe07d54c549dd537311230e127
Autor:
Mihai Ancău, Goutam Kumar Tanti, Vicki Marie Butenschoen, Jens Gempt, Igor Yakushev, Stephan Nekolla, Mark Mühlau, Christian Scheunemann, Sebastian Heininger, Benjamin Löwe, Erik Löwe, Silke Baer, Johannes Fischer, Judith Reiser, Sai S. Ayachit, Friederike Liesche-Starnecker, Jürgen Schlegel, Kaspar Matiasek, Martina Schifferer, Jan S. Kirschke, Thomas Misgeld, Tim Lueth, Bernhard Hemmer
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104982- (2024)
Summary: Background: Inflammatory demyelinating diseases of the central nervous system, such as multiple sclerosis, are significant sources of morbidity in young adults despite therapeutic advances. Current murine models of remyelination have limited
Externí odkaz:
https://doaj.org/article/4152d6937b1f43938faedc49f705b2f9
Autor:
Razan Muhtadi, Denise Bernhardt, Gabriele Multhoff, Lisa Hönikl, Stephanie E. Combs, Sandro M. Krieg, Jens Gempt, Bernhard Meyer, Vahé Barsegian, Monika Lindemann, Mandy Kasper, Samantha Stewart, Matthias Port, Michael Abend, Christian D. Diehl, Patrick Ostheim
Publikováno v:
Cancers, Vol 16, Iss 13, p 2345 (2024)
GBM WHO CNS Grade 4 represents a major challenge for oncology due to its aggressive behavior. Conventional imaging has restrictions in detecting tumor recurrence. This prospective study aims to identify gene-based biomarkers in whole blood instead of
Externí odkaz:
https://doaj.org/article/838641d04d2e4b37b5d989122fb36a4e
Autor:
Laura Dieringer, Lea Baumgart, Laura Schwieren, Jens Gempt, Maria Wostrack, Bernhard Meyer, Vicki M. Butenschoen
Publikováno v:
Cancers, Vol 16, Iss 9, p 1782 (2024)
Introduction: Spinal intradural tumors account for 15% of all CNS tumors. Typical tumor entities include ependymomas, astrocytomas, meningiomas, and neurinomas. In cases of multiple affected segments, extensive approaches may be necessary to achieve
Externí odkaz:
https://doaj.org/article/465eeb96fb2141d3ac29637332fad80a
Autor:
Maria Waltenberger, Denise Bernhardt, Christian Diehl, Jens Gempt, Bernhard Meyer, Christoph Straube, Benedikt Wiestler, Jan J. Wilkens, Claus Zimmer, Stephanie E. Combs
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The brain is a common site for cancer metastases. In case of large and/or symptomatic brain metastases, neurosurgical resection is performed. Adjuvant radiotherapy is a standard procedure to minimize the risk of local recurrence a
Externí odkaz:
https://doaj.org/article/1a4db98d547744ea91eb51d3c5b5fd85