Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jens, Engelke"'
Autor:
Jennifer Jeck, Rebecca Kassubek, Jan Coburger, Simone Edenhofer, Stefan S. Schönsteiner, Albert C. Ludolph, Bernd Schmitz, Jens Engelke, Regine Mayer-Steinacker, Jan Lewerenz, Lars Bullinger
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 11 (2018)
Background: Despite multidisciplinary treatment approaches, the prognosis for patients with high-grade glioma (HGG) is poor, with a median overall survival (OS) of 14.6 months for glioblastoma multiforme (GB). As high levels of vascular endothelial g
Externí odkaz:
https://doaj.org/article/57e1c1e0ded047f79bd6a78df4953e55
Autor:
Katrin Nickel, Dirk Freudenstein, Elke Weimann, Minou Nadji-Ohl, Anne-Katrin Hickmann, Jan Coburger, Mirjam Renovanz, Lars Bullinger, Jens Engelke, Christian Rainer Wirtz, Jochem König, Linda Stöckelmaier, Oliver Ganslandt
Publikováno v:
Neurosurgical Review. 41:207-219
The objective of the present study is to assess the influence of extent of resection (EoR), use of intraoperative imaging, and awake surgery on health-related quality of life (HRQoL) in high-grade glioma (HGG) patients in a prospective multicenter st
Autor:
Ralph König, Mario Löhr, Stefan Schommer, Marie-Therese Forster, Katharina Faust, Andrej Pala, Minou Nadji-Ohl, Oliver Ganslandt, Stefan Rückriegel, Christian Senft, Bernd Schmitz, Ralf Ingo Ernestus, Franziska Löbel, Florian Ringel, Mirjam Renovanz, Dietrich Rothenbacher, Christian von der Brelie, Marcos Tatagiba, Constantin Roder, Peter Vajkoczy, Nadja Grübel, Jan Coburger, Gabriele Nagel, Jens Engelke, Veit Rohde, Christian Rainer Wirtz
Publikováno v:
Journal of neurological surgery. Part A, Central European neurosurgery. 81(1)
Background World Health Organization (WHO) grade II low-grade gliomas (LGGs) in adults are rare, and patients' mean overall survival (OS) is relatively long. Epidemiological data on factors influencing tumor genesis and progression are scarce, and pr
Autor:
Annika Dwucet, Michal Hlavac, Richard E. Kast, Marc-Eric Halatsch, Georg Karpel-Massler, Klaus-Michael Debatin, Mike-Andrew Westhoff, Markus D. Siegelin, Jens Engelke, Christian Rainer Wirtz
Publikováno v:
Cellular oncology (Dordrecht). 42(3)
Anti-apoptotic and pro-migratory phenotypes are hallmarks of neoplastic diseases, including primary brain malignancies. In this work, we examined whether reprogramming of the apoptotic and migratory machineries through a multi-targeting approach woul
Autor:
Andrej, Pala, Minou, Nadji-Ohl, Katharina, Faust, Stefan, Rückriegel, Constantin, Roder, Christian, von der Brelie, Marie-Therese, Forster, Franziska, Löbel, Stefan, Schommer, Mario, Löhr, Nadja, Grübel, Dietrich, Rothenbacher, Ralph, König, Jens, Engelke, Bernd, Schmitz, Christian Rainer, Wirtz, Christian, Senft, Veit, Rohde, Marcos, Tatagiba, Ralf Ingo, Ernestus, Peter, Vajkoczy, Oliver, Ganslandt, Gabriele, Nagel, Jan, Coburger, Florian, Ringel, Mirjam, Renovanz
Publikováno v:
Journal of Neurological Surgery Part A: Central European Neurosurgery. 81:e1-e1
Autor:
Christian Rainer Wirtz, Michal Hlavac, Jens Engelke, Richard E. Kast, Siegelin, A Westhoff, Marc-Eric Halatsch, Georg Karpel-Massler, Annika Dwucet
Publikováno v:
27th Annual Meeting of the working group “Experimental Neuro-Oncology”.
Autor:
Albert C. Ludolph, Bernd Schmitz, Lars Bullinger, Regine Mayer-Steinacker, Simone Edenhofer, Jennifer Jeck, Rebecca Kassubek, Stefan S. Schönsteiner, Jan Lewerenz, Jan Coburger, Jens Engelke
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 11 (2018)
Therapeutic Advances in Neurological Disorders
Therapeutic Advances in Neurological Disorders
Background: Despite multidisciplinary treatment approaches, the prognosis for patients with high-grade glioma (HGG) is poor, with a median overall survival (OS) of 14.6 months for glioblastoma multiforme (GB). As high levels of vascular endothelial g
Autor:
Michal Hlavac, Jens Engelke, Markus D. Siegelin, Christian Rainer Wirtz, Annika Dwucet, Richard E. Kast, Mike-Andrew Westhoff, Marc-Eric Halatsch, Georg Karpel-Massler
Publikováno v:
Neuro-Oncology. 20:vi96-vi97
The purpose of this study was to examine whether inhibition of RAC1 would enhance the pro-apoptotic reprogramming of glioblastoma’s cellular circuitry following selective Bcl-2/Bcl-xL inhibition by BH-3 mimetics. Preclinical drug testing and molecu
Autor:
Dietmar Rudolf Thal, Christian Rainer Wirtz, Jan Coburger, Michal Hlavac, Jens Engelke, Ralph König, Angelika Scheuerle
Publikováno v:
World Neurosurgery. 82:366-375
Objective Conventional curved or sector array ultrasound (cioUS) is the most commonly used intraoperative imaging modality worldwide. Although highly beneficial in various clinical applications, at present the impact of linear array intraoperative ul
Autor:
Thomas Simmet, Mike-Andrew Westhoff, Jens Engelke, Selim Corbacioglu, Klaus-Michael Debatin, Simone Fulda, Lisa Nonnenmacher, Marc-Eric Halatsch, Georg Karpel-Massler
Publikováno v:
International Journal of Cancer. 136:E173-E187
Glioblastoma is a highly aggressive, common brain tumor with poor prognosis. Therefore, this study examines a new therapeutic approach targeting oncogenic and survival pathways combined with common chemotherapeutics. The RIST (rapamycin, irinotecan,