Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jenny-Lee Panayides"'
Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review
Publikováno v:
Molecules, Vol 27, Iss 20, p 7026 (2022)
The insect nervous system is critical for its functional integrity. The cholinergic system, of which acetylcholinesterase (AChE) is a key enzyme, is essential to the Anopheles (consisting of major malaria vector species) nervous system. Furthermore,
Externí odkaz:
https://doaj.org/article/6d4382ac6abf43c3882e7fc9975ff119
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138607 (2015)
Despite the increased understanding of colorectal cancer and the introduction of targeted drug therapy, the metastatic phase of the disease remains refractory to treatment. Since the deregulation of normal apoptosis contributes to the pathogenesis of
Externí odkaz:
https://doaj.org/article/6c7e11db09a945eeb00b35a9b4e2c6e9
Publikováno v:
Mechanochemistry and Emerging Technologies for Sustainable Chemical Manufacturing ISBN: 9781003178187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2691bddfbc2094243737fedce0dba9d7
https://doi.org/10.1201/9781003178187-16
https://doi.org/10.1201/9781003178187-16
Publikováno v:
Reaction Chemistry & Engineering. 7:1718-1727
Ozonolysis is an attractive, efficient, and green means of introducing oxygen containing functionalities using only oxygen and electricity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d20117db6bd48c7c66c6840a696d973
https://doi.org/10.1039/d1re00554e
https://doi.org/10.1039/d1re00554e
Publikováno v:
Digital Discovery. 1:596-604
We report the development of an open-source software approach to monitor and control flow chemistry reactors from any smart device utilising Node-RED which lowers the expertise required to expand the system further and automate other equipment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae47d22743cc9ba86119ef6dd2606dd2
https://doi.org/10.1039/d2dd00036a
https://doi.org/10.1039/d2dd00036a
Autor:
Roderick T. Stark, Dominic R. Pye, Wenyi Chen, Oliver J. Newton, Benjamin J. Deadman, Philip W. Miller, Jenny-Lee Panayides, Darren L. Riley, Klaus Hellgardt, King Kuok (Mimi) Hii
A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the sustainability of the key steps of the reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9f055551c476d4e44a59076bcd63bd
http://hdl.handle.net/10044/1/99067
http://hdl.handle.net/10044/1/99067
Autor:
Jenny-Lee Panayides, Klaus Hellgardt, Simeng Wang, Christopher J. Tighe, Darren L. Riley, King Kuok (Mimi) Hii, Philip W. Miller
Publikováno v:
Reaction Chemistry & Engineering. 6:2018-2023
The functionalisation of imidazoles is a necessary step in the formation of many active pharmaceutical intermediates. Herein, we report a flow chemistry approach for the rapid and efficient formation of 2-lithio-1-(triphenylmethyl)imidazole at ambien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a6190e4b87438014e96343f5df76ec
https://doi.org/10.1039/d1re00343g
https://doi.org/10.1039/d1re00343g
Autor:
Darren L. Riley, Andre Stander, CJ Van der Westhuizen, Steenkamp, DG Van Greunen, Jenny-Lee Panayides, Margo Nell, Werner Cordier
Publikováno v:
Arkivoc. 2020:84-107
This work was supported by the National Research Foundation (NRF) of South Africa (Thuthuka grant number 106959), the University of Pretoria (Research and Development Program) and the Council for Scientific and Industrial Research (CSIR), South Afric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aec0ea2633f19f21a728ca9ed49205f
https://doi.org/10.24820/ark.5550190.p011.350
https://doi.org/10.24820/ark.5550190.p011.350
Autor:
Ian Wiid, Christopher J. Parkinson, Jenny Lee Panayides, Richard K. Haynes, Christiaan W. van der Westhuyzen
Publikováno v:
Medicinal Chemistry. 16:392-402
Background:With few exceptions, existing tuberculosis drugs were developed many years ago and resistance profiles have emerged. This has created a need for new drugs with discrete modes of action. There is evidence that tuberculosis (like other bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1e79349d850076cf534fabdbc8c36b
https://doi.org/10.2174/1573406415666190430143535
https://doi.org/10.2174/1573406415666190430143535
Publikováno v:
Journal of chemical information and modeling. 62(6)
Alzheimer's disease is the most common neurodegenerative disease and currently poses a significant socioeconomic problem. This study describes the uses of computer-aided drug discovery techniques to identify novel inhibitors of acetylcholinesterase,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f2a5e95e1f919146762e7c51750c5c
https://pubmed.ncbi.nlm.nih.gov/35139637
https://pubmed.ncbi.nlm.nih.gov/35139637