Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2 leading to universal blueprints for vaccine designs

Autor: Brandon Malone, Boris Simovski, Clément Moliné, Jun Cheng, Marius Gheorghe, Hugues Fontenelle, Ioannis Vardaxis, Simen Tennøe, Jenny-Ann Malmberg, Richard Stratford, Trevor Clancy

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

Abstract The global population is at present suffering from a pandemic of Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The goal of this study was to use artificial

Externí odkaz: https://doaj.org/article/b6083f2efc1b428fbf2eba0c45005e9d

Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2: toward universal blueprints for vaccine designs

Autor: Simen Tennøe, Jenny-Ann Malmberg, Brandon Malone, Jun Cheng, Ioannis Vardaxis, Hugues Fontenelle, Clément Moliné, Marius Gheorghe, Richard Stratford, Trevor Clancy, Boris Simovski

The global population is at present suffering from a pandemic of Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The goals of this study were to use artificial intelli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4f2d9eba67bd3921eed84b417cde2d

NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

Autor: Eva Sverremark-Ekström, Christelle Retière, David Price, Jakob Michaëlsson, Lisa L. Liu, Jenny-Ann Malmberg, Marie Schaffer, Andreas T. Björklund, Vivien Béziat, Karl-Johan Malmberg, John Trowsdale, James A. Traherne, Per Ljungman, Martin A. Ivarsson, Ebba Sohlberg, Hans-Gustaf Ljunggren

Publikováno v: Blood
Blood, American Society of Hematology, 2013, 121 (14), pp.2678-2688. ⟨10.1182/blood-2012-10-459545⟩
Blood, American Society of Hematology, 2013, 121 (14), pp.2678-2688. ⟨10.1182/blood-2012-10-459545.⟩

International audience; Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like receptors (KIRs) and their interactions with HLA class I molecules. As KIR expressionin a given NK cell is genetically hard-wired, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7f855cc6bc779e92ac2bb59fbc1997
https://doi.org/10.1182/blood-2012-10-459545

Tolerant and diverse natural killer cell repertoires in the absence of selection

Autor: Karl-Johan Malmberg, Sandra Andersson, Jenny-Ann Malmberg

Publikováno v: Experimental Cell Research. 316:1309-1315

Natural killer (NK) cells are innate lymphocytes that participate in the early control of viruses and tumors. The function of NK cells is under tight regulation by two complementary inhibitory receptor families that bind to classical and non-classica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d09a64d67ad6784e4d9159542e4879a
https://doi.org/10.1016/j.yexcr.2010.02.030

Resistive wall modes in the EXTRAP T2R reversed-field pinch

Autor: Dimitry Yadikin, Marco Cecconello, Jenny-Ann Malmberg, Per Brunsell

Publikováno v: Physics of Plasmas. 10:3823-3833

Resistive wall modes (RWM) in the reversed field pinch are studied and a detailed comparison of experimental growth rates and linear magnetohydrodynamic (MHD) theory is made. RWM growth rates are e ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3565ee3a3729f66dce29446bd2a68bb7
https://doi.org/10.1063/1.1604775