Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Jenny Y Wang"'
Autor:
Mijeong Kim, Manjot Singh, Bum-Kyu Lee, Moira Hibbs, Kirsty Richardson, Lesley Ellies, Larissa Wintle, Lisa M. Stuart, Jenny Y. Wang, Dominic C. Voon, Pilar Blancafort, Jianlong Wang, Jonghwan Kim, Peter J. Leedman, Andrew J. Woo
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract The MYC proto-oncogene (MYC) is one of the most frequently overexpressed genes in breast cancer that drives cancer stem cell-like traits, resulting in aggressive disease progression and poor prognosis. In this study, we identified zinc finge
Externí odkaz:
https://doaj.org/article/3a2eb9d8862b4252af620303b3ec1a97
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/4f3d33f056f5439099f651c3ce53cf68
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background Lateral flow devices (LFDs) are viral antigen tests for the detection of SARS-CoV-2 that produce a rapid result, are inexpensive and easy to operate. They have been advocated for use by the World Health Organisation to help contro
Externí odkaz:
https://doaj.org/article/8ec450a7d5684707b1425acf1fcf74a1
The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis
Autor:
Liu Teng, Yu Chen Feng, Su Tang Guo, Pei Lin Wang, Teng Fei Qi, Yi Meng Yue, Shi Xing Wang, Sheng Nan Zhang, Cai Xia Tang, Ting La, Yuan Yuan Zhang, Xiao Hong Zhao, Jin Nan Gao, Li Yuan Wei, Didi Zhang, Jenny Y. Wang, Yujie Shi, Xiao Ying Liu, Jin Ming Li, Huixia Cao, Tao Liu, Rick F. Thorne, Lei Jin, Feng-Min Shao, Xu Dong Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Genomic amplification of chromosome 3q often encodes proteins that contribute to cancer development. Here the authors identify a non-coding product of the 3q region, the lncRNA PLANE that promotes tumorigenesis through the deregulation of transcripti
Externí odkaz:
https://doaj.org/article/5b9cdaaeb58b43eabf91f4a962656e8e
Autor:
Pei Y. Liu, Andrew E. Tee, Giorgio Milazzo, Katherine M. Hannan, Jesper Maag, Sujanna Mondal, Bernard Atmadibrata, Nenad Bartonicek, Hui Peng, Nicholas Ho, Chelsea Mayoh, Roberto Ciaccio, Yuting Sun, Michelle J. Henderson, Jixuan Gao, Celine Everaert, Amy J. Hulme, Matthew Wong, Qing Lan, Belamy B. Cheung, Leming Shi, Jenny Y. Wang, Thorsten Simon, Matthias Fischer, Xu D. Zhang, Glenn M. Marshall, Murray D. Norris, Michelle Haber, Jo Vandesompele, Jinyan Li, Pieter Mestdagh, Ross D. Hannan, Marcel E. Dinger, Giovanni Perini, Tao Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
MYCN amplification is common in neuroblastomas. Here, the authors identify a long noncoding RNA, lncNB1 in these cancers and show that it promotes tumorigenesis by binding to ribosomal protein, RPL35 to enhance E2F1 and DEPDC1B protein synthesis, whi
Externí odkaz:
https://doaj.org/article/6f4020351a1c40b79a768a93d42a3e69
Autor:
Andrew J. Woo, Chelsea-Ann A. Patry, Alireza Ghamari, Gabriela Pregernig, Daniel Yuan, Kangni Zheng, Taylor Piers, Moira Hibbs, Ji Li, Miguel Fidalgo, Jenny Y. Wang, Joo-Hyeon Lee, Peter J. Leedman, Jianlong Wang, Ernest Fraenkel, Alan B. Cantor
Publikováno v:
Blood Advances, Vol 3, Iss 16, Pp 2499-2511 (2019)
Abstract: Erythroid maturation requires the concerted action of a core set of transcription factors. We previously identified the Krüppel-type zinc finger transcription factor Zfp148 (also called ZBP-89) as an interacting partner of the master eryth
Externí odkaz:
https://doaj.org/article/a4a01af35491446d8737b36cfb40774b
Autor:
Matthew Wong, Yuting Sun, Zhichao Xi, Giorgio Milazzo, Rebecca C. Poulos, Christoph Bartenhagen, Jessica L. Bell, Chelsea Mayoh, Nicholas Ho, Andrew E. Tee, Xiaoqiong Chen, Yang Li, Roberto Ciaccio, Pei Y. Liu, Chen C. Jiang, Qing Lan, Nisitha Jayatilleke, Belamy B. Cheung, Michelle Haber, Murray D. Norris, Xu D. Zhang, Glenn M. Marshall, Jenny Y. Wang, Stefan Hüttelmaier, Matthias Fischer, Jason W. H. Wong, Hongxi Xu, Giovanni Perini, Qihan Dong, Rani E. George, Tao Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Although the gain in chromosome 17q21-ter is commonly associated with neuroblastoma, it is not clear which gene of this region mediates tumorigenesis. Here, the authors are showing that JMJD6, which locates in that region, is a neuroblastoma tumorige
Externí odkaz:
https://doaj.org/article/a673d07528164588b51a22500785ed47
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100156- (2020)
Summary: Patient-derived xenografts (PDXs) are the most valuable tool for preclinical drug testing because they retain the genetic diversity and phenotypic heterogeneity of the original tumor. Acute myeloid leukemia (AML) remains difficult to engraft
Externí odkaz:
https://doaj.org/article/336f987c4cac4686917f8e814354334b
Autor:
Estrella Gonzales-Aloy, Patrick Connerty, Basit Salik, Bing Liu, Andrew J. Woo, Michelle Haber, Murray D. Norris, Jianlong Wang, Jenny Y. Wang
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
Externí odkaz:
https://doaj.org/article/436963bc0781433d9f72fe5803c06bc1
Autor:
Tao Liu, Hilda A. Pickett, Xu D. Zhang, Matthias Fischer, Michelle Haber, Murray D. Norris, Roger R. Reddel, Glenn M. Marshall, Patsie Polly, Jinyan Li, Alla Dolnikov, Karen L. MacKenzie, Mark J. Cowley, Isabelle Janoueix-Lerosey, Jenny Y. Wang, Valentina Boeva, Valerie Combaret, Jo Vandesompele, Pieter Mestdagh, Tracy M. Bryan, Qing Lan, Belamy B. Cheung, Bernard Atmadibrata, Hui Peng, Marie Wong, Nisitha Jayatilleke, Ning Xu, Toby N. Trahair, Christoph Bartenhagen, Chelsea Mayoh, Alvin Kamili, Jamie I. Fletcher, Ting La, Pei Y. Liu, Andrew E. Tee, Matthew Wong, Christopher Nelson, Jingwei Chen
Supplementary Figure S4. Combination of the BET bromodomain inhibitor I-BET762 and chemotherapy agents, but not proteasome inhibitors, induces cytotoxicity to normal cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1076053a3d7acbe1ccbe1d52d7c939cd
https://doi.org/10.1158/1078-0432.22479843.v1
https://doi.org/10.1158/1078-0432.22479843.v1