Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jenny Varley"'
Autor:
Javier Benitez, Siegfried Scherneck, Douglas F. Easton, Michael R. Stratton, Christine Maugard, Jocelyne Jacquemier, Suzanne Parry, G Evans, Jenny Varley, Teresa Wagner, Yves-Jean Bignon, L G Fulford, Carolin Nestle-Krämling, Jan G. M. Klijn, Jorge S. Reis-Filho, Fiona Lalloo, Frédérique Penault-Llorca, Rivas C, Marc van der Vijver, Lesley McGuffog, Neva E. Haites, Matthias W. Beckmann, Peter Devilee, Julian Peto, Cees J. Cornelisse, Ute Hamann, Sunil R. Lakhani, Edith Olah, Jenny Chang-Claude, Timothy Bishop, Peter A. Daly, Hanne Meijers-Heijboer, Paolo Radice, Hagay Sobol, Silvana Pilotti, Barry A. Gusterson
Publikováno v:
Clinical cancer research, 11(14), 5175-5180. American Association for Cancer Research Inc.
Clinical Cancer Research, 11(14), 5175-5180. American Association for Cancer Research Inc.
Clinical Cancer Research, 11(14), 5175-5180. American Association for Cancer Research Inc.
Purpose: To investigate the proportion of breast cancers arising in patients with germ line BRCA1 and BRCA2 mutations expressing basal markers and developing predictive tests for identification of high-risk patients. Experimental Design: Histopatholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954fc752e5c7e45beab91253ead2308c
https://doi.org/10.1158/1078-0432.CCR-04-2424
https://doi.org/10.1158/1078-0432.CCR-04-2424
Publikováno v:
British Journal of Cancer
We have examined 11 cases of childhood adrenocortical tumours for copy number changes using comparative genomic hybridization (CGH). The changes seen are highly consistent between cases, and are independent of tumour type (carcinoma versus adenoma) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d3fdabb1a0e837fb8a9bfaa6ce1a51
https://doi.org/10.1038/sj.bjc.6990691
https://doi.org/10.1038/sj.bjc.6990691
Autor:
Valgerdur Sigurdardottir, P Rio, Rosette Lidereau, M. W. Beckmann, Javier Benitez, Laura J. van't Veer, Siegfried Scherneck, Natasa Sever, K. Laake, Robert Winqvist, Ivan Bièche, Pia Huusko, Eva Skovlund, Susanne Seitz, Edith Olah, Jorunn E. Eyfjord, Annegien Broeks, Sarah J. Plummer, Yves-Jean Bignon, Marie Hélène Champème, Dieter Niederacher, Nigel K. Spurr, Virpi Launonen, Borut Peterlin, Anne-Marie Cleton-Jansen, Jenny Varley, Gavin R M White, Daniel Birnbaum, Anne Lise Børresen-Dale, Ana Osorio, Åke Borg, Marianna Sztan, Sigfridur Gudlaugsdottir, Graham Casey
Publikováno v:
Genes, Chromosomes and Cancer. 25:212-221
Among the chromosomal regions commonly undergoing deletions in breast tumors is 11q23.1. The genes that are targets for loss of heterozygosity (LOH) in this region is not yet established. One of the candidate genes located in this region is ATM, resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55920a584b6cee1e83a439747e057d9e
https://doi.org/10.1002/(sici)1098-2264(199907)25:3<212::aid-gcc3>3.0.co
https://doi.org/10.1002/(sici)1098-2264(199907)25:3<212::aid-gcc3>3.0.co
Autor:
Gavin R M White, Risto Bloigu, Rosette Lidereau, A. Osorio, Jenny Varley, Rosa B. Barkardottir, E. Olah, Siegfried Scherneck, Robert Winqvist, N. Spurr, Marie-Hélène Champème, Ivan Bièche, Javier Benitez, Daniel Birnbaum, Pia Huusko, Virpi Launonen, Åke Borg, N. Velikonja, Dieter Niederacher, K. Laake, Anne Lise Børresen-Dale, Susanne Seitz, Peter Devilee, Julius Gudmundsson, Y. J. Bignon, Marianna Sztan, P Rio, A. M. Cleton-Jansen, M. W. Beckmann, E. K. Geirsdottir, B. Peterlin
Publikováno v:
British Journal of Cancer. 80:879-882
High frequencies of loss of heterozygosity (LOH) in chromosome 11q22-qter have been observed in various malignancies, including breast cancer. Previous studies on breast carcinomas by Winqvist et al (Cancer Res 55: 2660-2664) have indicated that a su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ecb9afe60418eae89b502af00ca016e
https://doi.org/10.1038/sj.bjc.6690435
https://doi.org/10.1038/sj.bjc.6690435
Autor:
Gavin R M White, Daniel S. Liscia, Graham Casey, Maria Stack, Tiziania Venesio, David Jones, David Crichton, Erika L D Mitchell, Jenny Varley, Mauro Santibanez-Koref, Jim Heighway
Publikováno v:
Human Molecular Genetics. 4:2047-2055
The chromosome region 17p13.3 is thought to encode a tumour suppressor gene involved in sporadic breast cancer and other malignancies. Physical ordering of markers has been carried out by a series of multicolour fluorescent in situ hybridisation (FIS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b66c5f4dd1961c4271beed48cba7d8f
https://doi.org/10.1093/hmg/4.11.2047
https://doi.org/10.1093/hmg/4.11.2047
Autor:
Gail McGown, Mary R Thorncroft, Gavin R M White, Anna Kelsey, K. J. Tricker, Jenny Varley, D G R Evans, JM Birch
Publikováno v:
British Journal of Cancer
We report a Li-Fraumeni syndrome family in which we have detected a splice acceptor mutation in intron 3 of TP53. The mutation affects one of the invariant residues at the splice acceptor site, as a result of which two aberrant transcripts are produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1156dc9b2d19ece093f0495d499ed2fd
https://doi.org/10.1038/bjc.1998.631
https://doi.org/10.1038/bjc.1998.631
Autor:
Jenny, Varley
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 222
Germline TP53 mutations are responsible for the large majority of classic LFS families, and a smaller proportion of LFL families. In some of the families shown to have no germline TP53 mutation, germline hChk2 mutations have been described. In some c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee15f542e848c5371eb2bd1d7851dc47
https://pubmed.ncbi.nlm.nih.gov/12710683
https://pubmed.ncbi.nlm.nih.gov/12710683
Publikováno v:
Nature Genetics. 27:92-93
We collected data on a large cohort of families with features of Li-Fraumeni syndrome (LFS). To date we have identified germline TP53 mutations in 28 families: 20 of 25 classic LFS and 8 of 20 Li-Fraumeni−like. In addition we have identified germli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95f31b6ac3d833e6f96d540f620f626d
https://doi.org/10.1038/87342
https://doi.org/10.1038/87342
Autor:
Jenny Varley
Publikováno v:
Chromosome Research. 2:165-165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5142984f63873a80e502a7f9852ec315
https://doi.org/10.1007/bf01553496
https://doi.org/10.1007/bf01553496