Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jenny V. Tobin"'
Autor:
Susana S. Correia, Guang Liu, Sarah Jacobson, Sylvie G. Bernier, Jenny V. Tobin, Chad D. Schwartzkopf, Emily Atwater, Elisabeth Lonie, Sam Rivers, Andrew Carvalho, Peter Germano, Kim Tang, Rajesh R. Iyengar, Mark G. Currie, John R. Hadcock, Christopher J. Winrow, Juli E. Jones
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background Inflammation in the central nervous system (CNS) is observed in many neurological disorders. Nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO–sGC–cGMP) signaling plays an essential role in modulating n
Externí odkaz:
https://doaj.org/article/b9dc10997df94c7186de03737efe4dd1
Autor:
Ali R. Banijamali, Andrew E. Carvalho, James D. Wakefield, Peter Germano, Timothy C. Barden, Jenny V. Tobin, Daniel P. Zimmer, Jaime L. Masferrer, Albert T. Profy, Mark G. Currie, G. Todd Milne
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 2, Pp n/a-n/a (2020)
Abstract The pharmacokinetics (PK), metabolism, excretion, mass balance, and tissue distribution of [14C]praliciguat were evaluated following oral administration of a 3‐mg/kg dose in Sprague‐Dawley rats and in a quantitative whole‐body autoradi
Externí odkaz:
https://doaj.org/article/644e106f3d284338801984e64cb31af8
Autor:
Daniel P. Zimmer, Courtney M. Shea, Jenny V. Tobin, Boris Tchernychev, Peter Germano, Kristie Sykes, Ali R. Banijamali, Sarah Jacobson, Sylvie G. Bernier, Renee Sarno, Andrew Carvalho, Yueh-tyng Chien, Regina Graul, Emmanuel S. Buys, Juli E. Jones, James D. Wakefield, Gavrielle M. Price, Jennifer G. Chickering, G. Todd Milne, Mark G. Currie, Jaime L. Masferrer
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic 3',5' GMP (cGMP) signaling plays a central role in regulation of diverse processes including smooth muscle relaxation, inflammation, and fibrosis. sGC is activated by the short-lived physiologi
Externí odkaz:
https://doaj.org/article/e994be112c3a40db87031271143e9556
Autor:
Inmaculada Silos-Santiago, Pei Ge, Alexander P. Bryant, Currie Mark G, Caroline B. Kurtz, Sara R. Thomas, Angelika Fretzen, Derek Wachtel, Boris Tchernychev, Robert M. Solinga, Gerhard Hannig, Jenny V. Tobin, Craig E. Lunte, Marco M. Kessler
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 355:48-56
MRP4 mediates the efflux of cGMP and cAMP and acts as an important regulator of these secondary messengers, thereby affecting signaling events mediated by cGMP and cAMP. Immunofluorescence staining showed high MRP4 expression localized predominantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437eae29a0f2545dd978f28834a1f9a4
https://doi.org/10.1124/jpet.115.224329
https://doi.org/10.1124/jpet.115.224329
Autor:
Correia, Susana S.1 (AUTHOR), Liu, Guang1 (AUTHOR), Jacobson, Sarah1 (AUTHOR), Bernier, Sylvie G.1 (AUTHOR), Tobin, Jenny V.1 (AUTHOR), Schwartzkopf, Chad D.1 (AUTHOR), Atwater, Emily1 (AUTHOR), Lonie, Elisabeth2 (AUTHOR), Rivers, Sam1 (AUTHOR), Carvalho, Andrew1 (AUTHOR), Germano, Peter1 (AUTHOR), Tang, Kim2 (AUTHOR), Iyengar, Rajesh R.1 (AUTHOR), Currie, Mark G.1 (AUTHOR), Hadcock, John R.1 (AUTHOR), Winrow, Christopher J.1 (AUTHOR), Jones, Juli E.1 (AUTHOR) jjones@cyclerion.com
Publikováno v:
Journal of Neuroinflammation. 9/18/2021, Vol. 18 Issue 1, p1-13. 13p.
Autor:
Banijamali, Ali R.1 (AUTHOR), Carvalho, Andrew E.1 (AUTHOR), Wakefield, James D.1 (AUTHOR), Germano, Peter1 (AUTHOR) pgermano@cyclerion.com, Barden, Timothy C.1 (AUTHOR), Tobin, Jenny V.1 (AUTHOR), Zimmer, Daniel P.1 (AUTHOR), Masferrer, Jaime L.1 (AUTHOR), Profy, Albert T.1 (AUTHOR), Currie, Mark G.1 (AUTHOR), Todd Milne, G.1 (AUTHOR)
Publikováno v:
Pharmacology Research & Perspectives. Apr2020, Vol. 8 Issue 2, p1-14. 14p.
Autor:
Zimmer, Daniel P., Shea, Courtney M., Tobin, Jenny V., Tchernychev, Boris, Germano, Peter, Sykes, Kristie, Banijamali, Ali R., Jacobson, Sarah, Bernier, Sylvie G., Sarno, Renee, Carvalho, Andrew, Chien, Yueh-tyng, Graul, Regina, Buys, Emmanuel S., Jones, Juli E., Wakefield, James D., Price, Gavrielle M., Chickering, Jennifer G., Milne, G. Todd, Currie, Mark G.
Publikováno v:
Frontiers in Pharmacology; 4/8/2020, p1-18, 18p
Autor:
Shea, Courtney M., Price, Gavrielle M., Guang Liu, Sarno, Renee, Buys, Emmanuel S., Currie, Mark G., Masferrer, Jaime L.
Publikováno v:
American Journal of Physiology: Renal Physiology; jan2020, Vol. 318 Issue 1, pF148-F159, 12p, 1 Diagram, 9 Graphs
Publikováno v:
Drug Metabolism Reviews. Nov2008 Supplement 3, Vol. 40, p1-288. 288p. 3 Diagrams, 1 Chart, 5 Graphs.