Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jenny Sprooten"'
Autor:
Daniel Morales Borràs, Sara Verbandt, Markus Ausserhofer, Gregor Sturm, Jinyeong Lim, Gil Arasa Verge, Isaure Vanmeerbeek, Raquel S. Laureano, Jannes Govaerts, Jenny Sprooten, Yourae Hong, Rebecca Wall, Gert De Hertogh, Xavier Sagaert, Gabriele Bislenghi, André D’Hoore, Albert Wolthuis, Francesca Finotello, Woong-Yang Park, Stefan Naulaerts, Sabine Tejpar, Abhishek D. Garg
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-30 (2023)
Abstract CD8+ T cell activation via immune checkpoint blockade (ICB) is successful in microsatellite instable (MSI) colorectal cancer (CRC) patients. By comparison, the success of immunotherapy against microsatellite stable (MSS) CRC is limited. Litt
Externí odkaz:
https://doaj.org/article/b6bbbd98e72c4ea192406d7073bc5f95
Autor:
Jenny Sprooten, Raquel S. Laureano, Isaure Vanmeerbeek, Jannes Govaerts, Stefan Naulaerts, Daniel M. Borras, Lisa Kinget, Jitka Fucíková, Radek Špíšek, Lenka Palová Jelínková, Oliver Kepp, Guido Kroemer, Dmitri V. Krysko, An Coosemans, Rianne D.W. Vaes, Dirk De Ruysscher, Steven De Vleeschouwer, Els Wauters, Evelien Smits, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, Hans Wildiers, Paul M. Clement, Peter Vandenabeele, Laurence Zitvogel, Abhishek D. Garg
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTImmunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell death that activates, rather than suppresses, innate and adaptive immune responses. Such responses culminate into T cell-driven immunity against anti
Externí odkaz:
https://doaj.org/article/7008e019d7c247f4ac120beabac8edc7
Autor:
Sabine Tejpar, Abhishek D Garg, Louis Boon, Massimiliano Mazzone, Jenny Sprooten, Isaure Vanmeerbeek, Stefan Naulaerts, Raquel Salvador, Jannes Govaerts, Rosa Trotta, Samantha Pretto, Shikang Zhao, Sarah Trusso Cafarello, Joren Verelst, Maarten Jacquemyn, Martyna Pociupany, Susan M Schlenner, Dirk Daelemans
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4d74b171dccc4687ac58e89d21d9fc32
Autor:
Raquel S Laureano, Jenny Sprooten, Isaure Vanmeerbeerk, Daniel M Borras, Jannes Govaerts, Stefan Naulaerts, Zwi N Berneman, Benoit Beuselinck, Kalijn F Bol, Jannie Borst, an Coosemans, Angeliki Datsi, Jitka Fučíková, Lisa Kinget, Bart Neyns, Gerty Schreibelt, Evelien Smits, Rüdiger V Sorg, Radek Spisek, Kris Thielemans, Sandra Tuyaerts, Steven De Vleeschouwer, I Jolanda M de Vries, Yanling Xiao, Abhishek D Garg
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable development over recent decades. However, this field is currently in a state of flux toward niche-applications, owing to recent paradigm-shifts in immuno-oncology mobili
Externí odkaz:
https://doaj.org/article/be78d83094d145fe958410723c8c8404
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Non-invasive, immuno-dynamic, biomarkers positioned in cancer patient’s blood milieu with immuno-oncological applications are rare. We recently established a “first-in-class” serum functional immunodynamics status (sFIS) assay, wherein in vitro
Externí odkaz:
https://doaj.org/article/73f0cdc9ceb144bcbbfc7fc1c640c633
Autor:
Isaure Vanmeerbeek, Jannes Govaerts, Raquel S. Laureano, Jenny Sprooten, Stefan Naulaerts, Daniel M. Borras, Damya Laoui, Massimiliano Mazzone, Jo A. Van Ginderachter, Abhishek D. Garg
Publikováno v:
Cells, Vol 11, Iss 23, p 3890 (2022)
Tumour-associated macrophages (TAMs) are essential players in the tumour microenvironment (TME) and modulate various pro-tumorigenic functions such as immunosuppression, angiogenesis, cancer cell proliferation, invasion and metastasis, along with res
Externí odkaz:
https://doaj.org/article/8915dc7290e54dc2a42fb2582c530c49
Autor:
Antonia Carla Testa, Sabine Tejpar, Ignace Vergote, Valentina Chiappa, An Coosemans, Thaïs Baert, Chiara Landolfo, Wouter Froyman, Dirk Timmerman, Tom Bourne, Abhishek D Garg, Patrizia Agostinis, Louis Boon, Daniela Fischerova, Caroline Van Holsbeke, Jenny Sprooten, Ann Vankerckhoven, Isaure Vanmeerbeek, Daniel M Borras, Yani Berckmans, Roxanne Wouters, Raquel S Laureano, Dominique Schols
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/c7317b3b6a0e4a03af4f9f35a3b5424c
Autor:
Rianne D. W. Vaes, Kobe Reynders, Jenny Sprooten, Kathleen T. Nevola, Kasper M. A. Rouschop, Marc Vooijs, Abhishek D. Garg, Maarten Lambrecht, Lizza E. L. Hendriks, Marijana Rucevic, Dirk De Ruysscher
Publikováno v:
Cancers, Vol 13, Iss 24, p 6259 (2021)
Radiotherapy (RT) and chemotherapy can induce immune responses, but not much is known regarding treatment-induced immune changes in patients. This exploratory study aimed to identify potential prognostic and predictive immune-related proteins associa
Externí odkaz:
https://doaj.org/article/29890b130c934d278beb7755d3002095
Autor:
Isaure Vanmeerbeek, Jenny Sprooten, Dirk De Ruysscher, Sabine Tejpar, Peter Vandenberghe, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Abhishek D. Garg
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
The term ‘immunogenic cell death’ (ICD) denotes an immunologically unique type of regulated cell death that enables, rather than suppresses, T cell-driven immune responses that are specific for antigens derived from the dying cells. The ability o
Externí odkaz:
https://doaj.org/article/430f227a2bff4708a263f3d1cd73a5de
Autor:
Jenny Sprooten, Jolien Ceusters, An Coosemans, Patrizia Agostinis, Steven De Vleeschouwer, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Abhishek D. Garg
Publikováno v:
OncoImmunology, Vol 8, Iss 11 (2019)
Dendritic- cells (DCs) have received considerable attention as potential targets for the development of anticancer vaccines. DC-based anticancer vaccination relies on patient-derived DCs pulsed with a source of tumor-associated antigens (TAAs) in the
Externí odkaz:
https://doaj.org/article/c5ccb54faf214b31843b0797a54eda70