Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures

Autor: Unnur Styrkarsdottir, Gudmar Thorleifsson, Sigurjon A. Gudjonsson, Asgeir Sigurdsson, Jacqueline R. Center, Seung Hun Lee, Tuan V. Nguyen, Timothy C.Y. Kwok, Jenny S.W. Lee, Suzanne C. Ho, Jean Woo, Ping-C. Leung, Beom-Jun Kim, Thorunn Rafnar, Lambertus A. Kiemeney, Thorvaldur Ingvarsson, Jung-Min Koh, Nelson L.S. Tang, John A. Eisman, Claus Christiansen, Gunnar Sigurdsson, Unnur Thorsteinsdottir, Kari Stefansson

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)

Bone mineral density (BMD) is the best predictor of osteoporotic fracture risk. Here, the authors perform a genome wide association study in Icelanders and people of European and East-Asian descent, and identify a new allele in intron 15 of the PTCH1

Externí odkaz: https://doaj.org/article/75d57f6551dd4b3da89bfcd9e832ac35

A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients

Autor: Yuanyuan Wu, Cho Yiu Yung, Linda Lam, Ruby Siu-yin Lee, Vincent Mok, John P. Harrison, Vivian W Y Lee, Jenny S.W. Lee, Timothy Kwok, Grace Choi

Publikováno v: Kwok, T, Wu, Y, Lee, J, Lee, R, Yung, C Y, Choi, G, Lee, V, Harrison, J, Lam, L & Mok, V 2020, ' A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients ', Clinical Nutrition, vol. 39, no. 8, pp. 2399-2405 . https://doi.org/10.1016/j.clnu.2019.11.005
Clinical Nutrition, 39(8), 2399-2405. Churchill Livingstone

Summary Background & aims Mild cognitive impairment (MCI) patients are at risk of cognitive decline, while elevated serum homocysteine is also associated with cognitive impairment. Thus, older people with MCI and hyperhomocysteinemia may be under gre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06dcea5950c3ec91791da289f4a50cf
https://doi.org/10.1016/j.clnu.2019.11.005

COVID ‐19 and older people in Asia: Asian Working Group for Sarcopenia calls to action

Autor: Hidenori Arai, Wee Shiong Lim, Taro Kojima, Masafumi Kuzuya, Li Ning Peng, Chih Kuang Liang, Katsuya Iijima, Prasert Assantachai, Shu Lih Chia, Yunhwan Lee, Ken Sugimoto, Yew Yoong Ding, Wei Ju Lee, Masahiro Akishita, Shuji Kawashima, Jae Young Lim, Liang Kung Chen, Jenny S.W. Lee, Sang Yoon Lee, Miji Kim, Hak Chul Jang, Yin Wei Wang, Ming Yueh Chou, Jean Woo, Chang Won Won, Tung Wai Auyeung, Lin Kang, Ninie Y. Wang

Publikováno v: Geriatrics & Gerontology International

The coronavirus disease 2019 (COVID-19) pandemic has casted a huge impact on global public health and the economy. In this challenging situation, older people are vulnerable to the infection and the secondary effects of the pandemic and need special

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1ee1d2c4cb4a59af786601fb4968ca
https://doi.org/10.1111/ggi.13939

Pilot study on comparisons between the effectiveness of mobile video-guided and paper-based home exercise programs on improving exercise adherence, self-efficacy for exercise and functional outcomes of patients with stroke with 3-month follow-up: A single-blind randomized controlled trial

Autor: Claudia Sin Yi Sit, Tak Man Lo, Ka Yan Chan, Titanic Fuk On Lau, Charles Wai Kin Lai, Bryan Ping Ho Chung, Jenny S.W. Lee, Herman Lau, Chau Yee Yeung, Elsie Hui, Wendy Kam Ha Chiang

Publikováno v: Hong Kong Physiotherapy Journal
Hong Kong Physiotherapy Journal, Vol 40, Iss 1, Pp 63-73 (2020)

Objective: To compare the effectiveness of mobile video-guided home exercise program and standard paper-based home exercise program. Methods: Eligible participants were randomly assigned to either experimental group with mobile video-guided home exer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a9d20e3f728f998351a2596fdc09c00
https://doi.org/10.1142/s1013702520500079

Characterising frailty, metrics of continuous glucose monitoring, and mortality hazards in older adults with type 2 diabetes on insulin therapy (HARE): a prospective, observational cohort study

Autor: Ronald C.W. Ma, Elaine Chow, Leong-Ting Lui, King-Fai Cheng, Erik Fung, Behzad Nasiri Ahmadabadi, Elsie Hui, Gloria Hiu Wing Lau, Marjo-Riitta Järvelin, Suyi Xie, Lei Huang, Jenny S.W. Lee, Timothy Kwok, William B. Goggins, Yi Ting Chung, Joseph J.Y. Sung, Irwin King, Wing-Yee So, Queenie Chan

Publikováno v: The Lancet. Healthy longevity. 2(11)

Summary Background To our knowledge, no previous study has examined the inter-relationship between frailty, dysglycaemia, and mortality in frail older adults with type 2 diabetes who are on insulin therapy. We used continuous glucose monitors (CGMs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82bf6e3046d003607fbc205936e5073
https://pubmed.ncbi.nlm.nih.gov/36098024