Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jenny S Wong"'
Autor:
Kimberly Stegmaier, Jenny S Wong, Kenneth N Ross, Kwan T Chow, David Peck, Renee D Wright, Stephen L Lessnick, Andrew L Kung, Todd R Golub
Publikováno v:
PLoS Medicine, Vol 4, Iss 4, p e122 (2007)
The presence of tumor-specific mutations in the cancer genome represents a potential opportunity for pharmacologic intervention to therapeutic benefit. Unfortunately, many classes of oncoproteins (e.g., transcription factors) are not amenable to conv
Externí odkaz:
https://doaj.org/article/3348c2ae2b8649059a89ebaf6cc79b72
Autor:
Kristin Meliambro, Yanfeng Yang, Marina de Cos, Estefania Rodriguez Ballestas, Caroline Malkin, Jonathan Haydak, John R. Lee, Fadi Salem, Laura H. Mariani, Ronald E. Gordon, John M. Basgen, Huei Hsun Wen, Jia Fu, Evren U. Azeloglu, John Cijiang He, Jenny S. Wong, Kirk N. Campbell
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Despite recent progress in the identification of mediators of podocyte injury, mechanisms underlying podocyte loss remain poorly understood, and cell-specific therapy is lacking. We previously reported that kidney and brain expressed protein (KIBRA),
Externí odkaz:
https://doaj.org/article/427bdc10103645eb8f284f1c9af46d1b
Autor:
Kristin Meliambro, Xuezhu Li, Fadi Salem, Zhengzi Yi, Zeguo Sun, Lili Chan, Miriam Chung, Jorge Chancay, Ha My T. Vy, Girish Nadkarni, Jenny S. Wong, Jia Fu, Kyung Lee, Weijia Zhang, John C. He, Kirk N. Campbell
Publikováno v:
Kidney Medicine, Vol 3, Iss 4, Pp 653-658 (2021)
Recent case reports suggest that coronavirus disease 2019 (COVID-19) is associated with collapsing glomerulopathy in African Americans with apolipoprotein L1 gene (APOL1) risk alleles; however, it is unclear whether disease pathogenesis is similar to
Externí odkaz:
https://doaj.org/article/16a9a594ddad44c7b2f31898eee1b372
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Podocyte foot process effacement is a key histologic finding in proteinuric kidney disease. We previously showed that 3-week old CD2AP-deficient mice have significant proteinuria, glomerular hypertrophy and mesangial expansion. The goal o
Externí odkaz:
https://doaj.org/article/f82a8903a2fd462b86998602aafb5860
Autor:
Rhodora C. Calizo, Smiti Bhattacharya, J. G. Coen van Hasselt, Chengguo Wei, Jenny S. Wong, Robert J. Wiener, Xuhua Ge, Nicholas J. Wong, Jia-Jye Lee, Christina M. Cuttitta, Gomathi Jayaraman, Vivienne H. Au, William Janssen, Tong Liu, Hong Li, Fadi Salem, Edgar A. Jaimes, Barbara Murphy, Kirk N. Campbell, Evren U. Azeloglu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Kinase inhibitors used in chemotherapy are known for their adverse effects on kidney physiology. Here, Calizo et al. show that dasatinib is associated with a higher risk of glomerular toxicity compared to other kinase inhibitors, due to deleterious e
Externí odkaz:
https://doaj.org/article/8269d038cbb047b6863d44efd06fc28f
Publikováno v:
Allergy & Rhinology, Vol 9 (2018)
Allergy & Rhinology
Allergy & Rhinology
Background Photoelectrochemical oxidation (PECO) is a new air purification technology developed to reduce circulating indoor allergens. PECO removes particles as small as 0.1 nm with the destruction of organic matter otherwise not trapped by a tradit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92e4d614db3afa4476b9d08b8230ae2
https://doaj.org/article/d22c32849b0044039b78275541f45b65
https://doaj.org/article/d22c32849b0044039b78275541f45b65
Autor:
Jenny S. Wong, Kenneth N. Ross, Todd R. Golub, Kimberly Stegmaier, Daniel J. DeAngelo, Steven M. Corsello
Publikováno v:
Blood. 106:2841-2848
Cure rates for patients with acute myeloid leukemia (AML) remain low despite ever-increasing dose intensity of cytotoxic therapy. In an effort to identify novel approaches to AML therapy, we recently reported a new method of chemical screening based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c900b390f448df98f7f625f0abc529
https://doi.org/10.1182/blood-2005-02-0488
https://doi.org/10.1182/blood-2005-02-0488
Autor:
Petra Kern, Linghu Nie, Jenny S. Wong, Hsiu-Ching Chang, Torsten Witte, Xiaosong Wang, Nicolas Carvou
Publikováno v:
The Journal of Immunology. 171:867-874
CD8 glycoproteins are expressed as either alphaalpha homodimers or alphabeta heterodimers on the surface of T cells. CD8alphabeta is a more efficient coreceptor than the CD8alphaalpha for peptide Ag recognition by TCR. Each CD8 subunit is composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6ca34482a92d8f83f8c38b9c813a76
https://doi.org/10.4049/jimmunol.171.2.867
https://doi.org/10.4049/jimmunol.171.2.867
Autor:
Lee Ling Yang, Beatrice M. Tam, Jenny S. Wong, Robert E. Anderson, Martin-Paul Agbaga, Orson L. Moritz
Publikováno v:
Investigative Opthalmology & Visual Science. 55:3669
PURPOSE Autosomal dominant Stargardt macular dystrophy caused by mutations in the Elongation of Very Long Chain fatty acids (ELOVL4) gene results in macular degeneration, leading to early childhood blindness. Transgenic mice and pigs expressing mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ce5a3070d727bede66f16915be6aec
https://doi.org/10.1167/iovs.13-13099
https://doi.org/10.1167/iovs.13-13099
Autor:
Todd R. Golub, David Peck, Stephen L. Lessnick, Andrew L. Kung, Kwan T. Chow, Jenny S. Wong, Kenneth N. Ross, Renee D. Wright, Kimberly Stegmaier
Publikováno v:
PLoS Medicine, Vol 4, Iss 4, p e122 (2007)
PLoS Medicine
PLoS Medicine
Background The presence of tumor-specific mutations in the cancer genome represents a potential opportunity for pharmacologic intervention to therapeutic benefit. Unfortunately, many classes of oncoproteins (e.g., transcription factors) are not amena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c1ca6e2d335ea8823d253c38c9d1c7
https://doi.org/10.1371/journal.pmed.0040122
https://doi.org/10.1371/journal.pmed.0040122