Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jenny Q, Qian"'
Autor:
Jenny Q. Qian, Nina Thiessen, Daniela S. Gerhard, Yvonne Moyer, Shahab Asgharzadeh, Inanc Birol, Jun S. Wei, Baljit Kamoh, Marco A. Marra, Gad Getz, Javed Khan, Adam Kiezun, Stacey Gabriel, Angela Tam, Jaime M. Guidry Auvil, Wendy B. London, Lee Lichenstein, Scott L. Carter, Chip Stewart, Jaegil Kim, Malcolm A. Smith, Readman Chiu, Kristina A. Cole, Maura Diamond, Richard Sposto, Aaron McKenna, Martin Hirst, Matthew Meyerson, Allan Lo, Julie M. Gastier-Foster, Martin Krzywinski, Alireza Hadj Khodabakshi, Michael S. Lawrence, Andrew Wood, Steven J.M. Jones, Richard Corbett, Daniel Auclair, Michael D. Hogarty, Trevor J. Pugh, Carrie Sougnez, Lingyun Ji, Shaun D. Jackman, Richard A. Moore, Kristian Cibulskis, Robert C. Seeger, Yongjun Zhao, Megan Hanna, Edward F. Attiyeh, Sharon J. Diskin, Adrian Ally, Yael P. Mosse, Erica Shefler, Andrey Sivachenko, Olena Morozova, John M. Maris, Chandra Sekhar Pedamallu, Alex H. Ramos, Karen Mungall, Thomas C. Badgett, Eric S. Lander
Publikováno v:
PMC
Neuroblastoma is a malignancy of the developing sympathetic nervous system that often presents with widespread metastatic disease, resulting in survival rates of less than 50%. To determine the spectrum of somatic mutation in high-risk neuroblastoma,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde7933096e8f1c311518874ce855eaa
https://doi.org/10.1038/ng.2529
https://doi.org/10.1038/ng.2529
Autor:
Jennifer A. Chan, Richard A. Moore, Yaron S. Butterfield, Suganthi Chittaranjan, David N. Louis, Olena Morozova, J. Gregory Cairncross, Marlo Firme, Gloria Roldán, Marco Perizzolo, Charles Chesnelong, Inanc Birol, Samuel Weiss, Gregg B. Morin, Stephen Yip, Alexandra Maslova, Karen Mungall, Aly Karsan, Richard Corbett, Shaun D. Jackman, Sean D. Young, Readman Chiu, Richard Varhol, Marco A. Marra, Haiyan Li, Jessica Tamura-Wells, Eric Chuah, Jenny Q. Qian, Yongjun Zhao, Jianghong An, Nina Thiessen, Eric E. Smith, Rod Docking, Wei Wu, Andrew J. Mungall, Steven J.M. Jones, Annie Moradian, Michael D. Blough, Martin Hirst
Publikováno v:
The Journal of Pathology. 226:7-16
Oligodendroglioma is characterized by unique clinical, pathological, and genetic features. Recurrent losses of chromosomes 1p and 19q are strongly associated with this brain cancer but knowledge of the identity and function of the genes affected by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a48c37cefb5595e43eec989651cb1f8
https://doi.org/10.1002/path.2995
https://doi.org/10.1002/path.2995
Autor:
Jenny Q. Qian, Cydney B. Nielsen, Ryan D. Morin, Joseph M. Connors, Randy D. Gascoyne, Shaun D. Jackman, Jacqueline E. Schein, Richard Varhol, Martin Hirst, Doug Horsman, Yongjun Zhao, Steven J.M. Jones, Inanc Birol, Marco A. Marra, Greg Stazyk
Publikováno v:
Bioinformatics. 25:2872-2877
Motivation: Whole transcriptome shotgun sequencing data from non-normalized samples offer unique opportunities to study the metabolic states of organisms. One can deduce gene expression levels using sequence coverage as a surrogate, identify coding c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84721f61fee5cc061333ae3a7b88d552
https://doi.org/10.1093/bioinformatics/btp367
https://doi.org/10.1093/bioinformatics/btp367
Autor:
Yaron S.N. Butterfield, David Shih, Janet C. Lindsey, Olivier Ayrault, James T. Rutka, Carlos Gilberto Carlotti, Borja L. Holgado, Livia Garzia, Ji Yeoun Lee, Paul A. Northcott, Laura K. Donovan, K. A. Michealraj, Vijay Ramaswamy, Toshihiro Kumabe, Nada Jabado, Thomas Zeng, Michael A. Grotzer, Michael D. Taylor, Jessica Liu, Darlene Lee, Eric Chuah, Gudrun Fleischhack, Scott Zuyderduyn, Xi Huang, Andrey Korshunov, Jacqueline E. Schein, Steven C. Clifford, Ute Bartels, V. Peter Collins, Peter B. Dirks, Stuart Matan-Lithwick, Claudia C. Faria, Daniel W. Fults, Xiao-Nan Li, Tobey J. MacDonald, Yusanne Ma, Mikhail Bilenky, Inanc Birol, Gary D. Bader, Nina Thiessen, Anne Bendel, Marc Remke, Eloi Mercier, Alex Manno, Haiyan I. Li, William A. Weiss, Stéphanie Puget, Noreen Dhalla, Marco A. Marra, Wendy J. Ingram, Sohrab P. Shah, Stefan M. Pfister, Ulrich Schüller, José Pimentel, Jaroslav Sterba, Marcel Kool, Ronald L. Hamilton, Lei Qin, Seung-Ki Kim, An He, Trevor J. Pugh, Stephen C. Mack, Kory Zayne, Xin Wang, Yoon Jae Cho, Kyu-Chang Wang, Patryk Skowron, Betty Luu, Ian F. Pollack, Cynthia Hawkins, Erwin G. Van Meir, Salomeh Jelveh, Andrew J. Mungall, Caitlin Hoffman, Andrew W. Walter, Helen Wheeler, Adi Rolider, Young Cheng, Michael K. Cooper, A. Sorana Morrissy, Jüri Reimand, Uri Tabori, Michael Mayo, Hamza Farooq, Florence M.G. Cavalli, Maria Luisa Garrè, Eric Bouffet, Adrian Ally, Richard A. Moore, Yongjun Zhao, Duncan Stearns, William Long, Richard Corbett, Karel Zitterbart, Yisu Li, Jeffrey H. Wisoff, Tina Wong, Robert J. Wechsler-Reya, Simon Bailey, Yuan Yao Thompson, Lara S. Collier, Luca Massimi, Andrew R. Hallahan, Byung Kyu Cho, Torsten Pietsch, David Lyden, Teiji Tominaga, Angela Tam, James Garvin, Roger J. Packer, John Peacock, Jeffrey J. Olson, Karey Shumansky, Adam J. Dupuy, Kane Tse, David A. Largaespada, Sandra E. Dunn, David T.W. Jones, Young Shin Ra, Patricia Lindsay, Tarek Shalaby, Rebecca Carlsen, Patrick Plettner, Andrew Roth, Chelsea Mayoh, Karen Mungall, Charles G. Eberhart, Xiaochong Wu, Daniela Pretti da Cunha Tirapelli, Sofia Nunes, Jenny Q. Qian, David Malkin, Maura Massimino, John J.Y. Lee, Steven J.M. Jones, Stephan Tippelt, Carolina Nor, Noriyuki Kijima
Publikováno v:
Nature. 529(7586)
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. We treated a transposon-driven, functional genomic mouse model of medulloblastoma wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c59843844c6d06e9049c9cec0e69a2f
https://pubmed.ncbi.nlm.nih.gov/26831182
https://pubmed.ncbi.nlm.nih.gov/26831182
Autor:
Katayoon, Kasaian, Sam M, Wiseman, Nina, Thiessen, Karen L, Mungall, Richard D, Corbett, Jenny Q, Qian, Ka Ming, Nip, Ann, He, Kane, Tse, Eric, Chuah, Richard J, Varhol, Pawan, Pandoh, Helen, McDonald, Thomas, Zeng, Angela, Tam, Jacquie, Schein, Inanc, Birol, Andrew J, Mungall, Richard A, Moore, Yongjun, Zhao, Martin, Hirst, Marco A, Marra, Blair A, Walker, Steven J M, Jones
Publikováno v:
The Journal of pathology. 230(3)
Parathyroid carcinoma is a rare endocrine malignancy with an estimated incidence of less than 1 per million population. Excessive secretion of parathyroid hormone, extremely high serum calcium level, and the deleterious effects of hypercalcaemia are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ca7f1fb3a150e9848c0279fa77c5d4c
https://pubmed.ncbi.nlm.nih.gov/23616356
https://pubmed.ncbi.nlm.nih.gov/23616356
Autor:
Shaun D. Jackman, S. Cenk Sahinalp, Inanc Birol, Jenny Q. Qian, Sherry Wang, Pamela A. Hoodless, Nina Thiessen, Jeremy Parker, Andrew J. Mungall, Lucas Swanson, Yaron S. Butterfield, Readman Chiu, Richard A. Moore, Anthony Raymond, Donna E. Hogge, Richard Varhol, Yongjun Zhao, Aly Karsan, Ka Ming Nip, Angela Tam, Richard Corbett, Deniz Yorukoglu, Sandy Sung, Gordon Robertson, T. Roderick Docking, Karen Mungall
Publikováno v:
BioMed Central Ltd
BMC Genomics
BMC Genomics
Background: Chimeric transcripts, including partial and internal tandem duplications (PTDs, ITDs) and gene fusions, are important in the detection, prognosis, and treatment of human cancers. Results: We describe Barnacle, a production-grade analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd18bbcdd5d6f751ff8cd9cf57d1ba6d
http://hdl.handle.net/1721.1/81361
http://hdl.handle.net/1721.1/81361
Autor:
Jenny Q. Qian, Darell D. Bigner, Miklós Garami, Shaun D. Jackman, Wiesława Grajkowska, Nalin Gupta, Johan M. Kros, Poul H. Sorensen, Anna Kenney, Stéphanie Reynaud, Byung Kyu Cho, Ian F. Pollack, Marcel Kool, Steven C. Clifford, Kyu-Chang Wang, Inanc Birol, Tzvi Aviv, Hendrick Witt, Gemma Hoad, Martine F. Roussel, Christine Haberler, Pim J. French, Betty Luu, Cynthia Hawkins, Claudia C. Faria, Richard A. Moore, Karin M. Muraszko, Yuan Yao, Nanne K. Kloosterhof, Rameen Beroukhim, Leos Kren, Erna M.C. Michiels, Jan O. Korbel, Paul A. Northcott, Stefan M. Pfister, Marc Remke, Nina Thiessen, Jennifer A. Chan, Adam M. Fontebasso, Maryam Fouladi, Shin Jung, Richard G. Ellenbogen, Richard Corbett, László Bognár, Yoon Jae Cho, Massimo Zollo, Robert J. Wechsler-Reya, Steven E. Schumacher, Xing Fan, Michael J. Levy, Wolfram Scheurlen, Young Shin Ra, Adrian M. Stütz, William A. Weiss, Simon Bailey, Rajeev Vibhakar, Giuseppe Cinalli, Toshihiro Kumabe, Marco A. Marra, Christian R. Marshall, Eric Bouffet, Luca Massimi, Scott L. Pomeroy, Sarah S. Pernet-Fattet, Andrew J. Mungall, James T. Rutka, G. Yancey Gillespie, Charles G. Eberhart, Peter Hauser, Andy Chu, Jüri Reimand, Xiaochong Wu, Adi Rolider, Xin Wang, Stephen W. Scherer, Reid C. Thompson, Ka Ming Nip, Anne Jouvet, Timothy E. Van Meter, Robert A. Holt, Anthony Raymond, Livia Garzia, Teiji Tominaga, Erwin G. Van Meir, John Peacock, Michael D. Taylor, Achille Iolascon, Roger E. McLendon, Andrey Korshunov, Stephen C. Mack, Nada Jabado, Readman Chiu, Africa Fernandez-L, Eric Chuah, Richard Varhol, Hideo Nakamura, Samer K. Elbabaa, Uri Tabori, Peter B. Dirks, Gary D. Bader, Linda M. Liau, François Doz, Allan Lo, Janet C. Lindsey, Adrian M. Dubuc, Michelle Fèvre-Montange, David T.W. Jones, Carlos Gilberto Carlotti, Ali G. Saad, Steffen Albrecht, Michael K. Cooper, Karen Mungall, Daisuke Kawauchi, A. Sorana Morrissy, Boleslaw Lach, Karel Zitterbart, Joshua B. Rubin, Matthew Meyerson, Florence M.G. Cavalli, Yisu Li, Shenandoah Robinson, Marta Perek-Polnik, Olivier Delattre, David Malkin, Almos Klekner, James M. Olson, Steven J.M. Jones, Thomas Zichner, David W. Ellison, Seung-Ki Kim, Vijay Ramaswamy, Anath C. Lionel, David Shih, Jeffrey R. Leonard, Concezio Di Rocco
Publikováno v:
Nature, 488(7409), 49-56. Nature Publishing Group
Nature, vol. 488, no. 7409, pp. 49-56
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature, vol. 488, no. 7409, pp. 49-56
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive chemotherapy. As medulloblastoma exhibits marked intertumoural hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c0bed20006ff67a402d4b2087b84fc
https://pure.eur.nl/en/publications/e92d8a69-c09e-47f4-8909-50517a3013ba
https://pure.eur.nl/en/publications/e92d8a69-c09e-47f4-8909-50517a3013ba
Autor:
Malachi Griffith, Karen Mungall, Steven J.M. Jones, Richard A. Moore, Rong She, Marco A. Marra, Shaun D. Jackman, Yaron S. Butterfield, Richard Newsome, Pamela A. Hoodless, Yongjun Zhao, Richard Corbett, Angela Tam, Hisanaga Mark Okada, Martin Hirst, Timothee Cezard, Inanc Birol, Baljit Kamoh, Richard Varhol, Anna Liisa Prabhu, Simon K. Chan, Gordon Robertson, Readman Chiu, Matthew A. Field, Jenny Q. Qian, Nina Thiessen, Anthony Raymond, Jacqueline E. Schein, Sam Lee
Publikováno v:
Nature methods. 7(11)
We describe Trans-ABySS, a de novo short-read transcriptome assembly and analysis pipeline that addresses variation in local read densities by assembling read substrings with varying stringencies and then merging the resulting contigs before analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8691fa912e813d756b8a6f2e6c3a9a6
https://pubmed.ncbi.nlm.nih.gov/20935650
https://pubmed.ncbi.nlm.nih.gov/20935650
Autor:
Jenny Q. Qian, Andrew J. Mungall, Yongjun Zhao, Karen Mungall, Richard A. Moore, Elizabeth J. Perlman, Marco A. Marra, Daniela S. Gerhard, Kelsey Zhu, Jacquie Schein, Yussanne Ma, Hye Jung E. Chun
Publikováno v:
Cancer Research. 74:3087-3087
Rhabdoid tumors (RT) of the kidney (RTK) are aggressive pediatric solid tumors that predominantly affect infants. There is no effective chemotherapy and the overall 4-year survival rate is 23%. RT has a characteristic loss of SMARCB1 function, found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::883326e4114ba9d48a73dccf8a42ea0c
https://doi.org/10.1158/1538-7445.am2014-3087
https://doi.org/10.1158/1538-7445.am2014-3087
Autor:
Karen Mungall, Jacquie Schein, Inna Shlafman, Yussanne Ma, Kane Tse, Saeed Saberi, Andrew J. Mungall, Elizabeth J. Perlman, Marco A. Marra, Emilia L. Lim, Mikhail Bilenky, Annaick Carles, An He, Erin Pleasance, Daniela S. Gerhard, Hye Jung E. Chun, Michelle Ng, Steven J.M. Jones, Jenny Q. Qian, Veronique G. LeBlanc, Eric Chuah, Nina Thiessen, Martin Hirst, Diana L. Palmquist, Michael D. Taylor, Rodrigo Goya, Richard A. Moore, Yong Jun Zhao, Kelsey Zhu, Alireza Heravi-Moussavi, William Long, Tina Wong
Publikováno v:
Cancer Cell. (3):394-406
Summary Malignant rhabdoid tumors (MRTs) are rare lethal tumors of childhood that most commonly occur in the kidney and brain. MRTs are driven by SMARCB1 loss, but the molecular consequences of SMARCB1 loss in extra-cranial tumors have not been compr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc9f763dec87ecf4d6d5870a6d43b16