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Novel immunosuppressive properties of interleukin‐6 in dendritic cells: inhibition of NF‐κB binding activity and CCR7 expression

Autor: Jenny Pahne, Subramanya Hegde, Sigrun Smola-Hess

Publikováno v: The FASEB Journal. 18:1439-1441

Interleukin-6 (IL-6) is produced during bacterial and viral infections and by various malignant tumors. Here, we describe novel immunosuppressive properties of IL-6 in dendritic cells (DC). In the presence of GM-CSF, IL-4, and a maturation stimulus,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ceba9ef349984595cd2c79170ae917d
https://doi.org/10.1096/fj.03-0969fje

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Expression of membrane type 1 matrix metalloproteinase in papillomavirus-positive cells: role of the human papillomavirus (HPV) 16 and HPV8 E7 gene products

Autor: Cornelia Mauch, Herbert Pfister, Sigrun Smola-Hess, Paola Zigrino, Hans Smola, Jenny Pahne

Publikováno v: The Journal of general virology. 86(Pt 5)

Matrix metalloproteinases (MMPs) degrade extracellular matrix. They are involved in cellular proliferation, migration, angiogenesis, invasion and metastasis. MT-1 MMP, a membrane-bound MMP, is expressed in carcinomas of the uterine cervix in vivo. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5369fbcb78fb656b09833b5c7ca818aa
https://pubmed.ncbi.nlm.nih.gov/15831939

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