Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jenny M. Baxter"'
Autor:
Jenny M. Baxter, Maria Teresa Diez, Fernando Pelaez, Craig A. Parish, Kenneth E. Wilson, Samantha Tucker-Samaras, Scott K. Smith, Mercedes de la Cruz, Javier Collado, Deborah L. Zink, Gonzalo Platas, Francisca Vicente, Gerald F. Bills
Publikováno v:
Journal of Natural Products. 72:59-62
Antisense-based screening strategies can be used to sensitize a microorganism and selectively detect inhibitors against a particular cellular target of interest. A strain of Staphylococcus aureus that generates an antisense RNA against SecA, a centra
Autor:
Ian W. Davies, Michael Palucki, Eugenia Njolito, Jason J. Kowal, Wenjie Li, Jonathan D. Rosen, Jenny M. Baxter, Jacob M. Janey, Rick Sidler, Orella Charles J
Publikováno v:
The Journal of Organic Chemistry. 73:3212-3217
An expedient, five step synthesis of caprolactam 1 is reported starting from natural L-homoserine. The key step is a chemoselective reductive cyclization of alpha,beta-unsaturated nitrile 10 mediated by Raney-Co type metals. This hydrogenation is ext
Autor:
Kevin M. Belyk, Ian W. Davies, Shane W. Krska, Dietrich Steinhuebel, Brian C. Bishop, Jenny M. Baxter, Anthony Alorati, Michael Palucki, Yongkui Sun
Publikováno v:
Organic Letters. 12:4201-4203
A general method for the enantioselective hydrogenation of protected allylic amine derivatives is described. This procedure relies on the generation of a cationic ruthenium complex with the axially chiral ligand (-)-TMBTP. The utility is highlighted
Autor:
Gonzalo Platas, Craig A. Parish, Jenny M. Baxter, Javier Collado, Joann Huber, Karen Dorso, George K. Abruzzo, Antonio Gonzalez, Francisca Vicente, Maria Teresa Diez, Kenneth E. Wilson
Publikováno v:
Journal of Natural Products. 67:1900-1902
The isolation and structure elucidation of 1 from the Basidomycete fungus Baeospora myosura is described. This new ene-triyne antibiotic was most potent against Gram-positive bacteria, while it was less active against Gram-negative bacteria and a yea
Autor:
James L. Leighton, Jenny M. Baxter Vu
Publikováno v:
ChemInform. 42
Bishomoallylic benzoic hydrazides are prepared via reaction of silyl ketene imines with acylhydrazones in the presence of the chiral silane Lewis acid HSLA under conditions A) or B).
Autor:
James L. Leighton, Jenny M. Baxter Vu
Publikováno v:
Organic letters. 13(15)
A new two-step synthesis of highly substituted pyrrolidines has been developed. Chiral silane Lewis acid promoted enantioselective Mannich reactions of silyl ketene imines with acylhydrazones may be used to access bishomoallylic benzoic hydrazides th
Publikováno v:
ChemInform. 42
The reactions allow efficient asymmetric access to α-aryl-β-hydrazido esters and α,α-disubstituted β-hydrazido nitriles.
Publikováno v:
Organic letters. 13(4)
Mannich reactions with chiral silicon Lewis acid activated acylhydrazones and α-aryl silyl ketene acetals and α-aryl,α-alkyl silyl ketene imines proceed efficiently and with good to excellent levels of both diastereoselectivity and enantioselectiv
Publikováno v:
ChemInform. 37
[reaction: see text] Herein we demonstrate functionalized enol tosylates to be robust substrates that undergo Suzuki-Miyaura, Sonogashira, and Stille cross-coupling reactions to provide stereodefined trisubstituted unsaturated esters.
Publikováno v:
ChemInform. 36