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of 6
pro vyhledávání: '"Jenny Ljusberg"'
Autor:
Göran Andersson, Maria Norgård, Riku Kiviranta, Barbro Ek-Rylander, Jenny Ljusberg, Serhan Zenger, Karin Hollberg
Publikováno v:
Bone. 41:820-832
Tartrate-resistant acid phosphatase (TRAP) is an enzyme highly expressed in osteoclasts and thought to participate in osteoclast-mediated bone turnover. Cathepsin K (Ctsk) is the major collagenolytic cysteine proteinase expressed in osteoclasts and h
Publikováno v:
Biochemistry. 40:11614-11622
Mammalian purple acid phosphatases (PAPs) can be divided into two groups, which exhibit distinct spectroscopic and kinetics properties: PAPs that consist of a single 36 kDa polypeptide, and PAPs that have undergone limited proteolysis to give two fra
Publikováno v:
Biochemical Journal. 343:63-69
Purple acid phosphatases (PAPs) are binuclear acid metallohydrolases also referred to as tartrate-resistant acid phosphatases (TRAPs) or type 5 acid phosphatases. The cDNA sequences of TRAP/PAP enzymes from different species and organs indicate that
Autor:
Kerstin Andersson, Tomas Barkhem, Göran Andersson, Barbro Ek-Rylander, Lars Öhman, Jenny Ljusberg
Publikováno v:
Biochemical Journal. 321:305-311
The tartrate-resistant acid phosphatase (TRAP) of rat osteoclasts has been shown to exhibit high (85Ő94%) identity at the amino acid sequence level with the purple acid phosphatase (PAP) from bovine spleen and with pig uteroferrin. These iron-contai
Autor:
Barbro Ek-Rylander, Robert Dodds, Maria Norgård, Yunling Wang, Kjell Hultenby, Pernilla Lång, Göran Andersson, Jenny Ljusberg
Publikováno v:
The Journal of biological chemistry. 280(31)
Tartrate-resistant acid phosphatase (TRAP) is a metallophosphoesterase participating in osteoclast-mediated bone turnover. Activation of TRAP is associated with the redox state of the di-iron metal center as well as with limited proteolytic cleavage
Autor:
Barbro Ek-Rylander, Jenny Ljusberg-SjÖLander, Pernilla Lång, Maria Norgård, Göran Andersson, Karin Hollberg, Shi-Jin Zhang, Yunling Wang
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 18(10)
TRACP is synthesized as a latent proenzyme requiring proteolytic processing to attain maximal phosphatase activity. Excision of an exposed loop domain abolishes the interaction between the loop residue Asp146 and a ligand to the redox-sensitive iron