Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jenny L. Whitlock"'
Autor:
Michael J. Allen, Jérome J. Lacroix, Srinivasan Ramachandran, Ricardo Capone, Jenny L. Whitlock, Ghanashyam D. Ghadge, Morton F. Arnsdorf, Raymond P. Roos, Ratnesh Lal
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 831-838 (2012)
Point mutations in the gene encoding copper–zinc superoxide dismutase (SOD1) impart a gain-of-function to this protein that underlies 20–25% of all familial amyotrophic lateral sclerosis (FALS) cases. However, the specific mechanism of mutant SOD
Externí odkaz:
https://doaj.org/article/1e5212b449004cdd8c77cbbfb81a3e01
Autor:
Srinivasan Ramachandran, Ghanashyam D. Ghadge, Raymond P. Roos, Michael J. Allen, Morton F. Arnsdorf, Ratnesh Lal, Jenny L. Whitlock, Ricardo Capone, Jerome J. Lacroix
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 831-838 (2012)
Point mutations in the gene encoding copper-zinc superoxide dismutase (SOD1) impart a gain-of-function to this protein that underlies 20-25% of all familial amyotrophic lateral sclerosis (FALS) cases. However, the specific mechanism of mutant SOD1 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79c53aecfb2a0760714439e286e96c3
http://www.sciencedirect.com/science/article/pii/S096999611100297X
http://www.sciencedirect.com/science/article/pii/S096999611100297X
Publikováno v:
Physics in Medicine and Biology. 50:305-318
A novel alpha-particle irradiator has recently been developed that provides the ability to characterize cell response. The irradiator is comprised of a collimated, planar alpha-particle source which, from below, irradiates cells cultured on a track-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af909fc97c175143da7ca30cbf47b71d
https://doi.org/10.1088/0031-9155/50/2/009
https://doi.org/10.1088/0031-9155/50/2/009
Autor:
Richard C. Reba, John Westman, Christina Soyland, Sindre P. Hassfjell, Jacob Rotmensch, Thomas G. Stinchcomb, Jenny L. Whitlock, Steven J. Wang, John C. Roeske
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 18:481-487
A new type of alpha-particle irradiator allows survival of each cell to be observed individually along with the size and shape of its nucleus and the positions of the hits it receives. This paper discusses methods of data analysis that can utilize th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adddf825a8b60edca692d9a80ddc0212
https://doi.org/10.1089/108497803322285242
https://doi.org/10.1089/108497803322285242
Autor:
Jenny L. Whitlock, Thomas G. Stinchcomb, Richard C. Reba, Christina Soyland, Steven J. Wang, John C. Roeske, Sindre P. Hassfjell, Jacob Rotmensch
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 18:425-430
In cases where both the source and cell geometry are well known, track-etch dosimetry allows the potential for individual cell dosimetry. However, analysis of track-etch images is both tedious and time-consuming. We describe here several image proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d892a984c6cb16c574c726407840f6
https://doi.org/10.1089/108497803322285170
https://doi.org/10.1089/108497803322285170
Autor:
E. Philip Horwitz, and Richard C. Reba, Mark L. Dietz, Jacob Rotmensch, John C. Roeske, Jenny L. Whitlock, John J. Hines, Christopher M. Straus
Publikováno v:
Industrial & Engineering Chemistry Research. 39:3135-3139
Cancer comprises a group of diseases characterized by the uncontrolled growth of abnormal cells that spread from the anatomical site of origin. For many types of cancer, surgery alone has proven inadequate, necessitating a broader approach to treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fff9d8fd77b69c79446319c0f6d2dd37
https://doi.org/10.1021/ie000425u
https://doi.org/10.1021/ie000425u
Publikováno v:
ract. 79:127-130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23c6f27d441b001e6597ae7386e66528
https://doi.org/10.1524/ract.1997.79.2.127
https://doi.org/10.1524/ract.1997.79.2.127
Autor:
Jacob Rotmensch, Jeff D. Shadley, Jenny L. Whitlock, Jeffrey L. Schwartz, Robert W. Atcher, Jian Tang
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 248:73-83
We investigated the radiobiological effects of the radon daughter bismuth-212 (212Bi) in Chinese hamster ovary (CHO) K1 cells and in xrs-5 cells, which are X-ray sensitive and deficient in the ability to rejoin DNA double-strand breaks. The cells wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf035cad336f25c1842ee62fd6902b3
https://doi.org/10.1016/0027-5107(91)90089-7
https://doi.org/10.1016/0027-5107(91)90089-7
Autor:
Steven M. Dudek, Morton F. Arnsdorf, Jenny L. Whitlock, Joe G.N. Garcia, Konstantin G. Birukov, Fernando Teran Arce, Ratnesh Lal, Anna A. Birukova
Disruption of pulmonary endothelial cell (EC) barrier function is a critical pathophysiologic event in highly morbid inflammatory conditions such as sepsis and acute respiratory disease stress syndrome. Actin cytoskeleton, an essential regulator of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d380f863456daffaa17d34492a3dad
https://europepmc.org/articles/PMC2440433/
https://europepmc.org/articles/PMC2440433/
Autor:
Christina Soyland, John C. Roeske, Jenny L. Whitlock, Jacob Rotmensch, Thomas G. Stinchcomb, Richard C. Reba, Steven J. Wang, Sindre P. Hassfjell
Publikováno v:
Cancer biotherapyradiopharmaceuticals. 18(3)
A computer-controlled, alpha-particle irradiator is described that allows for the measurement of the number and location of alpha-particle hits to individual cell nuclei, and subsequent scoring of cell survival. Cells are grown on a track-etch materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30dd5a89a016c3e34b5fd4e3cd7ae12
https://pubmed.ncbi.nlm.nih.gov/12954131
https://pubmed.ncbi.nlm.nih.gov/12954131