Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jenny L, Scott"'
Autor:
Anthony J. Day, Douglas P. Dyer, Nikolaos Kouvatsos, Leela C Biant, Jennifer M. Thomson, Caroline M. Milner, Andrew Price, Sanjay Anand, Eckart Bartnik, Jenny L Scott, Matthias Herrmann, Sheona P Drummond, Thomas Leeuw
Publikováno v:
Osteoarthritis and Cartilage.
ObjectivesTo investigate the role of endogenous TSG-6 in human osteoarthritis (OA) and assess the disease-modifying potential of a TSG-6-based biological treatment in cell, explant and animal models of OA.MethodsKnee articular cartilages from OA pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d3fc25757917baa910be09d877c244
https://doi.org/10.1016/j.joca.2023.05.013
https://doi.org/10.1016/j.joca.2023.05.013
Autor:
Andrew D. Rowan, Simon T. Donell, Auriane P. M. Destrument, K.L. Culley, Tracey E. Swingler, Steve Fenwick, Wang Hui, Jenny L. Scott, Ian M. Clark, David Young, Matt J. Barter, Rose K Davidson
Publikováno v:
Arthritis & Rheumatism. 65:1822-1830
Objective To examine the ability of a broad-spectrum histone deacetylase (HDAC) inhibitor to protect cartilage in vivo, and to explore the effects of class-selective HDAC inhibitors and small interfering RNA (siRNA)–induced knockdown of HDACs on me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a42eb33d5e30dc857c18c18edbde5e5
https://doi.org/10.1002/art.37965
https://doi.org/10.1002/art.37965
Autor:
Jennifer M. Thomson, Anthony J. Day, Giles Hassall, Caroline M. Milner, Ioannis Kanakis, Jenny L Scott, Matthew Hardman
Publikováno v:
Bone Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bebb7a407ffbb1f0618e299c719e63fb
https://doi.org/10.1530/boneabs.3.pp313
https://doi.org/10.1530/boneabs.3.pp313
Autor:
Kirsty L, Culley, Wang, Hui, Matt J, Barter, Rose K, Davidson, Tracey E, Swingler, Auriane P M, Destrument, Jenny L, Scott, Simon T, Donell, Steve, Fenwick, Andrew D, Rowan, David A, Young, Ian M, Clark
Publikováno v:
Arthritis and rheumatism. 65(7)
To examine the ability of a broad-spectrum histone deacetylase (HDAC) inhibitor to protect cartilage in vivo, and to explore the effects of class-selective HDAC inhibitors and small interfering RNA (siRNA)-induced knockdown of HDACs on metalloprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf353431b89ed041d5e3e3178e5d6064
https://pubmed.ncbi.nlm.nih.gov/23628768
https://pubmed.ncbi.nlm.nih.gov/23628768
Autor:
David Young, Martin Galler, Yaobo Xu, Catherine Bui, Louise N. Reynard, Jenny L. Scott, Andrew D. Rowan, Matt J. Barter
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(7)
Osteoarthritis is a degenerative joint disease characterized by a progressive and irreversible loss of the articular cartilage, due in main part to the cleavage of type II collagen within the matrix by the enzyme matrix metalloproteinase (MMP)13. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9d631ddc011a5cd49ef1398805927a
https://pubmed.ncbi.nlm.nih.gov/22505473
https://pubmed.ncbi.nlm.nih.gov/22505473
Autor:
Jenny L, Scott, Christos, Gabrielides, Rose K, Davidson, Tracey E, Swingler, Ian M, Clark, Gillian A, Wallis, Raymond P, Boot-Handford, Tom B L, Kirkwood, Robert W, Taylor, Robert W, Talyor, David A, Young
Background Oxidative stress is proposed as an important factor in osteoarthritis (OA). Objective To investigate the expression of the three superoxide dismutase (SOD) antioxidant enzymes in OA. Methods SOD expression was determined by real-time PCR a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1e9668d855f197a915b77268001c16
https://ueaeprints.uea.ac.uk/id/eprint/30151/
https://ueaeprints.uea.ac.uk/id/eprint/30151/
Publikováno v:
Molecular Immunology. 47:2288-2288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32bf5744212f2172c3a6615003282c1b
https://doi.org/10.1016/j.molimm.2010.05.267
https://doi.org/10.1016/j.molimm.2010.05.267