Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jenny L, Harry"'
Autor:
Lucille T. Sebastian, Michael Hsu, Andrew John Sloane, Peter T. P. Bye, Jenny L. Harry, Susanne K. Pedersen, Robyn A. Lindner, Sindhu S. Prasad, Ron P. Weinberger, Michael D. Robinson
Publikováno v:
Molecular & Cellular Proteomics. 4:1052-1060
Circulating antibodies can be used to probe protein arrays of body fluids, prepared by two-dimensional gel electrophoresis, for antigenic biomarker detection. However, detected proteins, particularly low abundance antigens, often remain unidentifiabl
Autor:
Nicolle H. Packer, Allan R. Glanville, Alan S. Verkman, Andrew John Sloane, Jenny L. Harry, Niclas G. Karlsson, Benjamin L. Schulz, Lucille T. Sebastian, Yuanlin Song, Leanne J. Robinson
Publikováno v:
Biochemical Journal. 387:911-919
SMG (submucosal gland) secretions are a major component of the airway surface liquid, are associated with innate immunity in the lung, and have been reported to be altered in lung disease. Changes in lung mucosal glycosylation have been reported in C
Autor:
Simon Melov, Ron P. Weinberger, Susan R. Doctrow, Jenny L. Harry, Douglas Hinerfeld, Bruce Cochran, Mathew Traini
Publikováno v:
Journal of Neurochemistry. 88:657-667
Oxidative stress and mitochondrial dysfunction have been linked to neurodegenerative disorders such as Parkinson's and Alzheimer's disease. However, it is not yet understood how endogenous mitochondrial oxidative stress may result in mitochondrial dy
Autor:
Jenny L. Harry, Jasmine Baker, Susanne K. Pedersen, Mathew Traini, John McCarthy, Marc R. Wilkins, Abi Manoharan, Nicolle H. Packer, Ben Herbert, Pier Giorgio Righetti, Andrew A. Gooley, Lucille T. Sebastian, Keith Leslie Williams
Publikováno v:
Journal of Proteome Research. 2:303-311
Abundant and hydrophilic nonmembrane proteins with isoelectric points below pH 8 are the predominant proteins identified in most proteomics projects. In yeast, however, low-abundance proteins make up 80% of the predicted proteome, approximately 50% h
Autor:
Jenny L. Harry, Rebecca Harcourt, Lionel Moulédous, Sybille Hunt, Howard B. Gutstein, Keith L. Williams
Publikováno v:
ELECTROPHORESIS. 24:296-302
Proteomic analysis is often performed on homogenized preparations of whole tissues, which does not provide any information about relevant biochemical changes in specific cell types. Laser-capture microdissection (LCM) is a technique that is precise e
Autor:
Rachel J. O’Neill, Jennifer A. Marshall Graves, Marilyn B. Renfree, Jenny L. Harry, Andrew J Pask, Geoffrey Shaw, Sharon L. Layfield
Publikováno v:
genesis. 33:131-139
In addition to an essential role in chondrogenesis, SOX9 is a highly conserved and integral part of the testis determining pathway in human and mouse. To determine whether SOX9 is involved in sex determination in noneutherian mammals we cloned a mars
Autor:
Nicolle H. Packer, Keith L. Williams, Jenny L. Harry, Ben Herbert, Andrew A. Gooley, Susanne K. Pedersen
Publikováno v:
Europe PubMed Central
Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) continues to deliver high quality protein resolution and dynamic range for the proteomics researcher. To remain as the preferred method for protein separation and characterization, several
Autor:
Stephen Alexander, Supriya Srinivasan, Jenny L. Harry, Hannah Alexander, Diane Sexton, Ben Herbert, Keith L. Williams, Mathew Traini
Publikováno v:
PROTEOMICS. 1:1119-1127
Secretion of spore coat proteins from the prespore secretory vesicles (PSVs) in Dictyostelium discoideum is a signal mediated event that underlies terminal cell differentiation, and represents an important case of developmentally regulated secretion.
Publikováno v:
PROTEOMICS. 1:186-193
Expressed Sequence Tags (ESTs) are an invaluable resource for protein identification and characterisation in proteomics. They allow proteins to be identified in the absence of genome sequence data. When EST sequences are used for protein identificati
Autor:
Keith L. Williams, Nicolle H. Packer, Marc R. Wilkins, Ben Herbert, Jenny L. Harry, Andrew A. Gooley
Publikováno v:
Electrophoresis. 21:1071-1081
Until recently scientists studied genes or proteins one at a time. With improvements in technology, new tools have become available to study the complex interactions that occur in biological systems. Global studies are required to do this, and these