Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jenny Kouretova"'
Autor:
Jenny Kouretova, M. Zouhir Hammamy, Anton Epp, Kornelia Hardes, Stephanie Kallis, Linlin Zhang, Rolf Hilgenfeld, Ralf Bartenschlager, Torsten Steinmetzer
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 712-721 (2017)
West Nile virus (WNV) and Dengue virus (DENV) replication depends on the viral NS2B-NS3 protease and the host enzyme furin, which emerged as potential drug targets. Modification of our previously described WNV protease inhibitors by basic phenylalani
Externí odkaz:
https://doaj.org/article/df59296dd14746238dbdef2356c9fe81
Autor:
Zhenzhen Zhang, Edwin Jun Chen Chew, Dahai Luo, Alvin Chew, Torsten Steinmetzer, Wint Wint Phoo, Melissa Wirawan, Jenny Kouretova
Publikováno v:
Antiviral Research. 160:17-24
Zika virus NS2B-NS3 protease plays an essential role in viral replication by processing the viral polyprotein into individual proteins. The viral protease is therefore considered as an ideal antiviral drug target. To facilitate the development of pro
Autor:
Niklas J. Braun, Heike Lang‐Henkel, Dahai Luo, Andreas Heine, Jenny Kouretova, Dorothee Rogge, Jun P. Quek, Torsten Steinmetzer, Simon Huber, Bing L. A. Chew, Ezekiel Z. K. Cheong
Publikováno v:
Chemmedchem
A series of cyclic active‐site‐directed inhibitors of the NS2B‐NS3 proteases from Zika (ZIKV), West Nile (WNV), and dengue‐4 (DENV4) viruses has been designed. The most potent compounds contain a reversely incorporated d‐lysine residue in t
Autor:
Stephanie Kallis, Anton Epp, M. Zouhir Hammamy, Jenny Kouretova, Ralf Bartenschlager, Rolf Hilgenfeld, Torsten Steinmetzer, Kornelia Hardes, Linlin Zhang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 712-721 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
West Nile virus (WNV) and Dengue virus (DENV) replication depends on the viral NS2B-NS3 protease and the host enzyme furin, which emerged as potential drug targets. Modification of our previously described WNV protease inhibitors by basic phenylalani