Výsledky vyhledávání - "Jenny Kienzler"

Akademický článek

Graphical and statistical analyses of the oculocardiac reflex during a non-invasive intracranial pressure measurement.

Autor: Yasin Hamarat, Laimonas Bartusis, Mantas Deimantavicius, Lina Siaudvytyte, Ingrida Januleviciene, Arminas Ragauskas, Eric M Bershad, Javier Fandino, Jenny Kienzler, Elke Remonda, Vaidas Matijosaitis, Daiva Rastenyte, Kestutis Petrikonis, Kristina Berskiene, Rolandas Zakelis

Publikováno v: PLoS ONE, Vol 13, Iss 4, p e0196155 (2018)

This study aimed to examine the incidence of the oculocardiac reflex during a non-invasive intracranial pressure measurement when gradual external pressure was applied to the orbital tissues and eye.Patients (n = 101) and healthy volunteers (n = 56)

Externí odkaz: https://doaj.org/article/540bc6ff36be45dc8afd3108f028c55a

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Linear accelerator–based radiosurgery for trigeminal neuralgia: comparative outcomes of frame-based and mask-based techniques

Autor: Jenny Kienzler, Alessandra Gorgulho, Hiro Sparks, Michael T. Selch, Tania Kaprealian, Won Kim, Fang-I Chu, Stephen Tenn, Nader Pouratian, Srinivas Chivukula, Nzhde Agazaryan, Antonio A.F. De Salles

Publikováno v: Journal of Neurosurgery. 137:217-226

OBJECTIVE Precise and accurate targeting is critical to optimize outcomes after stereotactic radiosurgery (SRS) for trigeminal neuralgia (TN). The aim of this study was to compare the outcomes after SRS for TN in which two different techniques were u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b4a22fbbd46428ab5c87300e8813a1
https://doi.org/10.3171/2021.8.jns21658

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IMMU-27. SIMULTANEOUS TARGETING OF THE PD-L1 AND THE TGF-Β PATHWAYS WITH BINTRAFUSP ALFA IN EXPERIMENTAL GLIOMAS

Autor: Manuela Silginer, Michael Weller, Jenny Kienzler, Nicolas Nunez, Yan Lan, Tobias Weiss, Burkhard Becher, Patrick Roth

Publikováno v: Neuro-Oncology. 24:vii137-vii137

Currently, immunotherapy is one of the most promising research areas in oncology, but immunotherapeutic strategies do not have proven clinical activity against glioblastoma so far. The immunosuppressive microenvironment of gliomas limits an appropria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be588aa0c1cb9ed986b021d7e4cef26c
https://doi.org/10.1093/neuonc/noac209.524

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TMIC-02. PRE-SURGICAL IMMUNE CHECKPOINT BLOCKADE RESHAPES THE IMMUNE LANDSCAPE AND SPATIAL ARCHITECTURE OF METASTATIC BRAIN TUMORS

Autor: Lu Sun, Jenny Kienzler, Jeremy Reynoso, Alexander Lee, Geoffrey Owens, Richard G Everson, David Nathanson, Timothy Cloughesy, Linda M Liau, Willy Hugo, Won Kim, Robert Prins

Publikováno v: Neuro-Oncology. 24:vii271-vii271

Brain tumors reside in a modified microenvironment where inflammatory processes are heavily regulated. Nevertheless, our recent study showed a significant immune infiltration in recurrent glioblastoma (rGBM) treated with neoadjuvant PD-1 checkpoint b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a50adc3e6a88ce940ea14ea83f68aed
https://doi.org/10.1093/neuonc/noac209.1046

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TAMI-01. NEOADJUVANT PD-1 ANTIBODY BLOCKADE REMODELS THE IMMUNE MICROENVIRONMENT OF METASTATIC BRAIN TUMORS

Autor: Won Kim, Frances Chow, Richard Everson, William H. Yong, Lu Sun, Alexander Lee, Jenny Kienzler, Willy Hugo, Carolina Chavez, Robert M. Prins

Publikováno v: Neuro Oncol

Brain metastases (BM) commonly arise in patients with melanoma, lung, and breast cancer. Currently, there are limited options for GBM and BM patients who have failed the first-line standard treatment, underscoring the importance of developing new the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5730827913e0c1fa9da1a373db789cfb
https://doi.org/10.1093/neuonc/noaa215.890

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TMIC-06. MYELOID POPULATIONS AND THE EFFECT OF NEOADJUVANT PD-1 INHIBITION IN THE GLIOBLASTOMA MICROENVIRONMENT: A SURFACEOMIC AND TRANSCRIPTOMIC DISSECTION AT THE SINGLE-CELL LEVEL

Autor: Robert M. Prins, Joey Orpilla, Mildred Galvez, Tom B. Davidson, Alexander Lee, Jenny Kienzler, Timothy F. Cloughesy, Linda M. Liau, Aaron Mochizuki, Anthony C. Wang, Frances Chow, Richard Everson

Publikováno v: Neuro Oncol

INTRODUCTION Glioblastoma (GBM) is the most common malignant brain tumor in adults and is associated with a dismal prognosis. Neoadjuvant anti-PD-1 blockade has demonstrated efficacy in melanoma, non-small cell lung cancer and recurrent GBM; however,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7c7c4393fb59b02a1ad489cde5a88e
https://europepmc.org/articles/PMC6845723/

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IMMU-33. IMMUNE PROFILING REVEALS INHIBITORY MACROPHAGES AND A DISTINCT SPATIAL DISTRIBUTION OF IMMUNE CELLS IN DIFFERENT TYPES OF BRAIN METASTASES

Autor: William H. Yong, Jeremy Reynoso, Alexander Lee, Robert M. Prins, Joey Orpilla, Aaron Mochizuki, Jenny Kienzler, Geoffrey C. Owens, Linda M. Liau

Publikováno v: Neuro Oncol

BACKGROUND Current treatment modalities, including surgical resection, radiosurgery and immune checkpoint inhibitors, have improved local control rates of brain metastases, but overall prognosis is still poor. AIM: To investigate the immune microenvi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739a844adeec4fa305ca950bd2a0187a
https://doi.org/10.1093/neuonc/noz175.525

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