Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jenny K W, Lam"'
Autor:
Simona Di Blasio, Maria Clarke, Charlotte K. Hind, Masanori Asai, Louis Laurence, Angelica Benvenuti, Mahnoor Hassan, Dorothy Semenya, DeDe Kwun-Wai Man, Victoria Horrocks, Giorgia Manzo, Sarah Van Der Lith, Carolyn Lam, Eugenio Gentile, Callum Annette, Janine Bosse, Yanwen Li, Barry Panaretou, Paul R. Langford, Brian D. Robertson, Jenny K. W. Lam, J. Mark Sutton, Michael McArthur, A. James Mason
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT 12-Bis-THA Cl2 [12,12′-(dodecane-1,12-diyl)-bis-(9-amino-1,2,3,4-tetrahydroacridinium) chloride] is a cationic bolalipid adapted from dequalinium chloride (DQC), a bactericidal anti-infective indicated for bacterial vaginosis (BV). Here, w
Externí odkaz:
https://doaj.org/article/8625d87284694eff9568dd55269bba7a
Autor:
Michele Verboni, Diego Romano Perinelli, Carol Yingshan Qiu, Mattia Tiboni, Annalisa Aluigi, Simone Lucarini, Jenny K. W. Lam, Andrea Duranti
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 223 (2023)
The delivery of therapeutics across biological membranes (e.g., mucosal barriers) by avoiding invasive routes (e.g., injection) remains a challenge in the pharmaceutical field. As such, there is the need to discover new compounds that act as drug per
Externí odkaz:
https://doaj.org/article/1a88ca53f78242048630ed75607cc1ce
Autor:
Zitong Shao, Waiting Tai, Yingshan Qiu, Rico C. H. Man, Qiuying Liao, Michael Y. T. Chow, Philip C. L. Kwok, Jenny K. W. Lam
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2044 (2021)
Multi-drug-resistant tuberculosis (MDR-TB) is a huge public health problem. The treatment regimen of MDR-TB requires prolonged chemotherapy with multiple drugs including second-line anti-TB agents associated with severe adverse effects. Capreomycin,
Externí odkaz:
https://doaj.org/article/7acc961ce28e4a4096146d3d5c9bb907
Autor:
Jenny K. W. Lam, Qi Zhou
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55502d04655bc7326b34598461b8a53d
https://doi.org/10.1007/s11095-023-03534-9
https://doi.org/10.1007/s11095-023-03534-9
Autor:
Harry W. Pan, Han Cong Seow, Jason C. K. Lo, Jinlin Guo, Lingqiao Zhu, Susan W. S. Leung, Chenghai Zhang, Jenny K. W. Lam
Publikováno v:
Pharmaceutical Research. 39:2291-2304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d81442549459498c7a2079499da1669
https://doi.org/10.1007/s11095-022-03331-w
https://doi.org/10.1007/s11095-022-03331-w
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 615 (2021)
The prospect of inhaled biologics has garnered particular interest given the benefits of the pulmonary route of administration. Pertinent considerations in producing inhalable dry powders containing biological medicines relate to aerosol performance
Externí odkaz:
https://doaj.org/article/f357b415c49c4ad6b0f32b53cfa32d1f
Publikováno v:
Pharmaceutical Research.
Introduction The emergence of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) posed a severe challenge to tuberculosis (TB) management. The treatment of MDR-TB involves second-line anti-TB agents, most of which are injectable and highly to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5434baa1e03e4a625f8603bd1f30e221
https://doi.org/10.1007/s11095-023-03488-y
https://doi.org/10.1007/s11095-023-03488-y
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1025 (2020)
In the last decade, biological drugs have rapidly proliferated and have now become an important therapeutic modality. This is because of their high potency, high specificity and desirable safety profile. The majority of biological drugs are peptide-
Externí odkaz:
https://doaj.org/article/19e00b7ad45e41c3bc2f064691239164
Autor:
DeDe Kwun-Wai Man, Tokuwa Kanno, Giorgia Manzo, Brian D. Robertson, Jenny K. W. Lam, A. James Mason
Publikováno v:
mSphere, Vol 3, Iss 4 (2018)
ABSTRACT The mycobacterial cell wall affords natural resistance to antibiotics. Antimicrobial peptides (AMPs) modify the surface properties of mycobacteria and can act synergistically with antibiotics from differing classes. Here, we investigate the
Externí odkaz:
https://doaj.org/article/30e2623b09474f2a90ca386387fab3dd
Autor:
Simona, Di Blasio, Maria, Clarke, Charlotte K, Hind, Masanori, Asai, Louis, Laurence, Angelica, Benvenuti, Mahnoor, Hassan, Dorothy, Semenya, DeDe Kwun-Wai, Man, Victoria, Horrocks, Giorgia, Manzo, Sarah, Van Der Lith, Carolyn, Lam, Eugenio, Gentile, Callum, Annette, Janine, Bosse, Yanwen, Li, Barry, Panaretou, Paul R, Langford, Brian D, Robertson, Jenny K W, Lam, J Mark, Sutton, Michael, McArthur, A James, Mason
Publikováno v:
mSphere.
12-Bis-THA Cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::288db37a7dc385e63136430bb1b005af
https://pubmed.ncbi.nlm.nih.gov/36511707
https://pubmed.ncbi.nlm.nih.gov/36511707