Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jenny Jaques"'
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Over the past years, a wide variety of in vivo mouse models have been generated in order to unravel the molecular pathology of Chronic Myeloid Leukemia (CML) and to develop and improve therapeutic approaches. These models range from (conditional) tra
Externí odkaz:
https://doaj.org/article/ac34a8bd8a1041e9bb36dbc9547aa4ce
RNA interference is a powerful tool to study loss-of-gene function in leukemic cells. Still, in order to identify effective novel treatment strategies to target and eradicate leukemic stem cells (LSCs), it is critically important to study gene functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf972cdf861a4079d473cb2e472ebf8
Autor:
Jan Jacob Schuringa, Huipin Yuan, Edo Vellenga, Antonella Antonelli, Bauke de Boer, Sarah J. Horton, Jenny Jaques, Joost D. de Bruijn, Richard W.J. Groen, Marco Carretta
Publikováno v:
Carretta, M, de Boer, B, Jaques, J, Antonelli, A, Horton, S J, Yuan, H, de Bruijn, J D, Groen, R W J, Vellenga, E & Schuringa, J J 2017, ' Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft models ', Experimental Hematology, vol. 51, pp. 36-46 . https://doi.org/10.1016/j.exphem.2017.04.008
Experimental Hematology, 51, 36-46. ELSEVIER SCIENCE INC
Experimental Hematology, 51, 36-46. Elsevier Inc.
Experimental Hematology, 51, 36-46. ELSEVIER SCIENCE INC
Experimental Hematology, 51, 36-46. Elsevier Inc.
Recently, NOD-SLID IL2R gamma(-/-) (NSG) mice were implanted with human mesenchymal stromal cells (MSCs) in the presence of ceramic scaffolds or Matrigel to mimic the human bone marrow (BM) microenvironment. This approach allowed the engraftment of l
Autor:
Anton C. M. Martens, Gert J. Ossenkoppele, Willy A. Noort, Jan Jacob Schuringa, Jenny Jaques, Antonella Antonelli, Andries C. Bloem, Annet Z. Brouwers-Vos, Regina de Jong-Korlaar, Joost D. de Bruijn, Jeroen F. van Velzen, Edo Vellenga, Linda Lubbers-Aalders, Huipin Yuan, Richard W.J. Groen, Bauke de Boer
Publikováno v:
Blood, 128(25), 2949-2959. AMER SOC HEMATOLOGY
Blood, 128(25), 2949-2959. American Society of Hematology
Antonelli, A, Noort, W A, Jaques, J, de Boer, B, de Jong-Korlaar, R, Brouwers-Vos, A Z, Lubbers-Aalders, L, van Velzen, J F, Bloem, A C, Yuan, H, de Bruijn, J D, Ossenkoppele, G J, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches ', Blood, vol. 128, no. 25, pp. 2949-2959 . https://doi.org/10.1182/blood-2016-05-719021, https://doi.org/10.1182/blood-2016-05719021
Blood, 128(25), 2949-2959. American Society of Hematology
Antonelli, A, Noort, W A, Jaques, J, de Boer, B, de Jong-Korlaar, R, Brouwers-Vos, A Z, Lubbers-Aalders, L, van Velzen, J F, Bloem, A C, Yuan, H, de Bruijn, J D, Ossenkoppele, G J, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches ', Blood, vol. 128, no. 25, pp. 2949-2959 . https://doi.org/10.1182/blood-2016-05-719021, https://doi.org/10.1182/blood-2016-05719021
To begin to understand the mechanisms that regulate self-renewal, differentiation, and transformation of human hematopoietic stem cells or to evaluate the efficacy of novel treatment modalities, stem cells need to be studied in their own species-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6e65245bc5af4d6523afc0239c8190
https://research.rug.nl/en/publications/5788e57c-1b76-4d71-b7b5-a42955af59bb
https://research.rug.nl/en/publications/5788e57c-1b76-4d71-b7b5-a42955af59bb