Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jenny J. Y. Chen"'
1
CD4 lymphocytes in the blood of HIV+ individuals migrate rapidly to lymph nodes and bone marrow: support for homing theory of CD4 cell depletion
Autor: Miles W. Cloyd, E. G. Briscoe, Jenny J.-Y. Chen, Mark E. Shirtliff, Jason C. Huang, S. A. Ali, Fernando Cesani, David P. Paar
Publikováno v: Journal of Leukocyte Biology. 72:271-278
The mechanism(s) by which human immunodeficiency virus (HIV) causes depletion of CD4 lymphocytes remains unknown. Evidence has been reported for a mechanism involving HIV binding to (and signaling) resting CD4 lymphocytes in lymphoid tissues, resulti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efdc7c2f13f4309192f4d650f3304094
https://doi.org/10.1189/jlb.72.2.271
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2
Detection of Antibodies to Human Immunodeficiency Virus (HIV) That Recognize Conformational Epitopes of Glycoproteins 160 and 41 Often Allows for Early Diagnosis of HIV Infection
Autor: Gautam K. Sahu, Liqiang Wang, David P. Paar, Jianmin Chen, John R. Petersen, Keith M. Ramsey, Miles W. Cloyd, Stephen K. Tyring, Alexander J. Indrikovs, Jenny J.-Y. Chen
Publikováno v: The Journal of Infectious Diseases. 186:321-331
On the basis of human immunodeficiency virus (HIV) needlestick studies, the time to seroconversion for anti-HIV antibodies is 1-9 months (mean, approximately 2-3 months). However, an earlier marker of an immune response to HIV often occurs-serum anti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a542777f2edfcd40c4918816673d16a
https://doi.org/10.1086/341661
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3
How Does HIV Cause Depletion of CD4 Lymphocytes? A Mechanism Involving Virus Signaling Through its Cellular Receptors
Autor: Miles W. Cloyd, Liqiang Wang, Patrick Adeqboyega, Jenny J.-Y. Chen
Publikováno v: Current Molecular Medicine. 1:545-550
HIV infection causes an acquired immunodeficiency, principally because of depletion of CD4 lymphocytes. The mechanism by which the virus depletes these cells, however, is not clearly understood. Since the virus predominantly infects CD4 lymphocytes i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a255532d8f4c19dcf86223626dd882
https://doi.org/10.2174/1566524013363320
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4
A Novel Mechanism of CD4 Lymphocyte Depletion Involves Effects of HIV on Resting Lymphocytes: Induction of Lymph Node Homing and Apoptosis Upon Secondary Signaling Through Homing Receptors
Autor: Liqiang Wang, Jenny J. Y. Chen, Benjamin B. Gelman, Rolf Konig, Miles W. Cloyd
Publikováno v: The Journal of Immunology. 162:268-276
Recently, we reported that abortive HIV infection of resting human T lymphocytes up-regulated expression of CD62L, the receptor for homing to lymph nodes (LNs), and enhanced homing of these cells from the blood into the LNs (Wang et al., 1997, Virolo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d39e4959b0e4c021429369e7fe980dac
https://doi.org/10.4049/jimmunol.162.1.268
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6
Apoptosis induced in HIV-1-exposed, resting CD4+ T cells subsequent to signaling through homing receptors is Fas/Fas ligand-mediated
Autor: Jiaxiang Ji, Miles W. Cloyd, Jenny J.-Y. Chen, Vivian L. Braciale
Publikováno v: Journal of leukocyte biology. 81(1)
The hallmark of HIV-1 disease is the gradual disappearance of CD4+ T cells from the blood. The mechanism of this depletion, however, is still unclear. Evidence suggests that lymphocytes die in lymph nodes, not in blood, and that uninfected bystander
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b2d6a414edf9a8911ca1eb0f33d98a
https://pubmed.ncbi.nlm.nih.gov/17056762
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7
CD4 lymphocytes in the blood of HIV(+) individuals migrate rapidly to lymph nodes and bone marrow: support for homing theory of CD4 cell depletion
Autor: Jenny J-Y, Chen, Jason C, Huang, Mark, Shirtliff, Elma, Briscoe, Seham, Ali, Fernando, Cesani, David, Paar, Miles W, Cloyd
Publikováno v: Journal of leukocyte biology. 72(2)
The mechanism(s) by which human immunodeficiency virus (HIV) causes depletion of CD4 lymphocytes remains unknown. Evidence has been reported for a mechanism involving HIV binding to (and signaling) resting CD4 lymphocytes in lymphoid tissues, resulti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b816d1757fc6529fff6b40a1d7efbd16
https://pubmed.ncbi.nlm.nih.gov/12149417
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8
Genetic variation in the 3' non-coding region of dengue viruses
Autor: Scott C. Weaver, Jenny J.-Y. Chen, Eryu Wang, Kevin L. Russell, Alan D.T. Barrett, Amy C. Shurtleff, Miguel T. Suderman, Renling Xu, Haolin Ni, Heiman Wang, Douglas M. Watts, David W.C. Beasley
Publikováno v: Virology. 281(1)
The 3' non-coding region (3'NCR) of strains of dengue 1 (DEN 1), DEN 2, DEN 3, and DEN 4 viruses, isolated in different geographical regions, was sequenced and compared to published sequences of the four dengue viruses. A total of 50 DEN 2 strains wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3386a4a13912556ab121d0a2a2fd7e9f
https://pubmed.ncbi.nlm.nih.gov/11222098
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9
How does HIV cause AIDS? The homing theory
Autor: Miles W. Cloyd, Liqiang Wang, Jenny J.-Y. Chen
Publikováno v: Molecular medicine today. 6(3)
The mechanism by which HIV causes depletion of CD4+ T cells in infected individuals remains unknown. Numerous theories have been proposed, but none can fully explain all of the events observed to occur in patients. Recent studies have shown that HIV
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ffb0c4474d2489c02f6aa15bffc238
https://pubmed.ncbi.nlm.nih.gov/10689313
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