Výsledky vyhledávání - "Jenny Hulkko"

The role of dendrin in IgA nephropathy

Autor: Anna Levin, Angelina Schwarz, Jenny Hulkko, Liqun He, Ying Sun, Peter Barany, Annette Bruchfeld, Maria Herthelius, Lars Wennberg, Kerstin Ebefors, Jaakko Patrakka, Christer Betsholtz, Jenny Nyström, Johan Mölne, Kjell Hultenby, Anna Witasp, Annika Wernerson

Background Immunoglobulin A nephropathy (IgAN) and its systemic variant IgA vasculitis (IgAV) damage the glomeruli, resulting in proteinuria, hematuria and kidney impairment. Dendrin is a podocyte-specific protein suggested to be involved in the path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc11423e694a25efb61874a6d890649
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-502256

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Neph1 Is Reduced in Primary Focal Segmental Glomerulosclerosis, Minimal Change Nephrotic Syndrome, and Corresponding Experimental Animal Models of Adriamycin-Induced Nephropathy and Puromycin Aminonucleoside Nephrosis

Autor: Jenny Hulkko, Jaakko Patrakka, Mark Lal, Karl Tryggvason, Kjell Hultenby, Annika Wernerson

Publikováno v: Nephron Extra
Nephron Extra, Vol 4, Iss 3, Pp 146-154 (2014)

Background/Aims: The transmembrane proteins Neph1 and nephrin form a complex in the slit diaphragm (SD) of podocytes. As recent studies indicate an involvement of this complex in the polymerization of the actin cytoskeleton and proteinuria, we wanted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4d44943f328a91c5b30a74168344fff8
http://europepmc.org/articles/PMC4202611

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Permeability, Ultrastructural Changes, and Distribution of Novel Proteins in the Glomerular Barrier in Early Puromycin Aminonucleoside Nephrosis

Autor: Jaakko Patrakka, Karl Tryggvason, Kjell Hultenby, Börje Haraldsson, Fredrik Dunér, Jenny Hulkko, Erna Pettersson, Karin Lindström, Annika Wernerson

Publikováno v: Nephron Experimental Nephrology. 116:e42-e52

Background/Aims: It is still unclear what happens in the glomerulus when proteinuria starts. Using puromycin aminonucleoside nephrosis (PAN) rats, we studied early ultrastructural and permeability changes in relation to the expression of the podocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4f1b77f00fcc9ff67adddc4682b467
https://doi.org/10.1159/000317130

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Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamics

Autor: Karl Tryggvason, Annika Wernerson, Hjalmar Brismar, Jaakko Patrakka, Christer Betsholtz, Jenny Hulkko, Björn Önfelt, Fredrik Dunér, Ljubica Perisic, Kjell Hultenby, Mathias Uhlén, Mark Lal, Timo Pikkarainen, Ying Sun

Publikováno v: Kidney international. 82(10)

Pleckstrin homology domain–containing, family H (with MyTH4 domain), member 2 (Plekhh2) is a 1491-residue intracellular protein highly enriched in renal glomerular podocytes for which no function has been ascribed. Analysis of renal biopsies from p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec57d14dc88fbf7f926029e5f67e76b6
https://pubmed.ncbi.nlm.nih.gov/22832517

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