Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jenny Hansson"'
Autor:
Sudip Ghosh, Maria Jassinskaja, Mina Davoudi, Melina Claesson Stern, Ugarit Daher, Mohamed Eldeeb, David Bryder, Jenny Hansson
Publikováno v:
HemaSphere, Vol 7, p e932515d (2023)
Externí odkaz:
https://doaj.org/article/f2600bb5110e49daa9babecdafdc2c10
Autor:
Alexander Mattebo, Taha Sen, Maria Jassinskaja, Kristýna Pimková, Isabel Prieto González-Albo, Abdul Ghani Alattar, Ramprasad Ramakrishnan, Stefan Lang, Marcus Järås, Jenny Hansson, Shamit Soneji, Sofie Singbrant, Emile van den Akker, Johan Flygare
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The YPEL family genes are highly conserved across a diverse range of eukaryotic organisms and thus potentially involved in essential cellular processes. Ypel4, one of five YPEL family gene orthologs in mouse and human, is highly and specific
Externí odkaz:
https://doaj.org/article/5dc977dcbe104bb4b3fa8157f49bbc12
Autor:
Maria Jassinskaja, Jenny Hansson
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Fetal and adult hematopoiesis are regulated by largely distinct sets of cell-intrinsic gene regulatory networks as well as extracellular cues in their respective microenvironment. These ontogeny-specific programs drive hematopoietic stem and progenit
Externí odkaz:
https://doaj.org/article/6f06b09c2927429f90d0d6ed98d11409
Autor:
Maria Jassinskaja, Kristýna Pimková, Nejc Arh, Emil Johansson, Mina Davoudi, Carlos-Filipe Pereira, Ewa Sitnicka, Jenny Hansson
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108894- (2021)
Summary: The process of hematopoiesis is subject to substantial ontogenic remodeling that is accompanied by alterations in cellular fate during both development and disease. We combine state-of-the-art mass spectrometry with extensive functional assa
Externí odkaz:
https://doaj.org/article/cf5b5f27760c4796b3e9796e54bf9bee
Autor:
Marie E Jönsson, Per Ludvik Brattås, Charlotte Gustafsson, Rebecca Petri, David Yudovich, Karolina Pircs, Shana Verschuere, Sofia Madsen, Jenny Hansson, Jonas Larsson, Robert Månsson, Alexander Meissner, Johan Jakobsson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
DNA methylation plays an important role in silencing transposable elements. Here the authors find that loss of DNMT1 and DNA methylation leads to transcriptional activation and chromatin remodelling of evolutionarily young—hominoid-specific —LINE
Externí odkaz:
https://doaj.org/article/0010acf9352643ada962a4e79869dc29
Autor:
Hongzhe Li, Hooi-Ching Lim, Dimitra Zacharaki, Xiaojie Xian, Keane J.G. Kenswil, Sandro Bräunig, Marc H.G.P. Raaijmakers, Niels-Bjarne Woods, Jenny Hansson, Stefan Scheding
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Human bone marrow stromal cells (BMSC) are key elements of the hematopoietic environment and they play a central role in bone and bone marrow physiology. However, how key stromal cell functions are regulated is largely unknown. We analyzed the role o
Externí odkaz:
https://doaj.org/article/112ede8630034c80ae41aed380c93728
Autor:
Axel Hyrenius-Wittsten, Mattias Pilheden, Helena Sturesson, Jenny Hansson, Michael P. Walsh, Guangchun Song, Julhash U. Kazi, Jian Liu, Ramprasad Ramakrishan, Cristian Garcia-Ruiz, Stephanie Nance, Pankaj Gupta, Jinghui Zhang, Lars Rönnstrand, Anne Hultquist, James R. Downing, Karin Lindkvist-Petersson, Kajsa Paulsson, Marcus Järås, Tanja A. Gruber, Jing Ma, Anna K. Hagström-Andersson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
In acute leukemia with KMT2A rearrangements (KMT2A-R), activating signaling mutations are common. Here, the authors use a retroviral acute myeloid mouse leukemia model to show that subclonal de novo activating mutations drive clonal evolution in acut
Externí odkaz:
https://doaj.org/article/90c8b9707fb44780aabe13e7a04984b5
Autor:
Maria Jassinskaja, Emil Johansson, Trine Ahn Kristiansen, Hugo Åkerstrand, Kristoffer Sjöholm, Simon Hauri, Johan Malmström, Joan Yuan, Jenny Hansson
Publikováno v:
Cell Reports, Vol 21, Iss 11, Pp 3285-3297 (2017)
Hematopoietic stem and progenitor cells (HSPCs) in the fetus and adult possess distinct molecular landscapes that regulate cell fate and change their susceptibility to initiation and progression of hematopoietic malignancies. Here, we applied in-dept
Externí odkaz:
https://doaj.org/article/f4ba9aaa9a5e4bedbf2385c9b2d2c359
Autor:
Daniel Klimmeck, Nina Cabezas-Wallscheid, Alejandro Reyes, Lisa von Paleske, Simon Renders, Jenny Hansson, Jeroen Krijgsveld, Wolfgang Huber, Andreas Trumpp
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 858-875 (2014)
Hematopoietic stem cells possess lifelong self-renewal activity and generate multipotent progenitors that differentiate into lineage-committed and subsequently mature cells. We present a comparative transcriptome analysis of ex vivo isolated mouse mu
Externí odkaz:
https://doaj.org/article/84d7b9a49fdf4193b76542e60f501c67
Autor:
Jenny Hansson, Mahmoud Reza Rafiee, Sonja Reiland, Jose M. Polo, Julian Gehring, Satoshi Okawa, Wolfgang Huber, Konrad Hochedlinger, Jeroen Krijgsveld
Publikováno v:
Cell Reports, Vol 2, Iss 6, Pp 1579-1592 (2012)
Generation of induced pluripotent stem cells (iPSCs) is a process whose mechanistic underpinnings are only beginning to emerge. Here, we applied in-depth quantitative proteomics to monitor proteome changes during the course of reprogramming of fibrob
Externí odkaz:
https://doaj.org/article/5c5edf437e564bb4a08f43c5d9a1f7ef