Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jenny G. Ryu"'
Autor:
Yuanxi Xu, Xiaoqin Li, Yasuhiro Tsume, Wenpeng Zhang, Bryan D. Yestrepsky, Jenny G. Ryu, Scott D. Larsen, Meghan E. Breen, Hongmin Sun, Roderick Joseph Sorenson, Walajapet Rajeswaran, Duxin Sun, Michael W. Wilson
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:1880-1897
Resistance to antibiotics is an increasingly dire threat to human health that warrants the development of new modes of treating infection. We recently identified 1 (CCG-2979) as an inhibitor of the expression of streptokinase, a critical virulence fa
Autor:
Scott D. Larsen, Susan M. Wade, Andrew J. Kocab, Nicole L. Harzdorf, Jessica L. Bell, H. D. Hollis Showalter, Richard R. Neubig, Jenny G. Ryu, Chris R. Evelyn
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(2)
We recently identified bis(amide) CCG-1423 (1) as a novel inhibitor of RhoA/C-mediated gene transcription that is capable of inhibiting invasion of PC-3 prostate cancer cells in a Matrigel model of metastasis. An initial structure-activity relationsh