Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jenny G Parvani"'
Autor:
Jessica C Price, Elham Azizi, L A Naiche, Jenny G Parvani, Priyanka Shukla, Seoyeon Kim, Jill K Slack-Davis, Dana Pe'er, Jan K Kitajewski
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233962 (2020)
High grade serous ovarian cancer (HGSC) is the most common and deadly type of ovarian cancer, largely due to difficulties in early diagnosis and rapid metastasis throughout the peritoneal cavity. Previous studies have shown that expression of Notch3
Externí odkaz:
https://doaj.org/article/859f06055ba54676af88902989d693e6
Autor:
Frank E. Jones, Edi Brogi, Samuel M. Lesko, Jenny G. Parvani, Tamika T. Duplessis, Yun Zhu, Stella U. Okamgba, Michael J. Brumlik, Doyel Mitra
The HER2-targeted therapy trastuzumab is widely used for the treatment of patients with metastatic breast tumors overexpressing HER2. However, an objective response is observed in only 12% to 24% of patients treated with trastuzumab as a single agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8a27878f5ab9d8f8d30ebcfff12d2c
https://doi.org/10.1158/1535-7163.c.6531818.v1
https://doi.org/10.1158/1535-7163.c.6531818.v1
Autor:
Frank E. Jones, Edi Brogi, Samuel M. Lesko, Jenny G. Parvani, Tamika T. Duplessis, Yun Zhu, Stella U. Okamgba, Michael J. Brumlik, Doyel Mitra
Supplementary Data from An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8156baa739bd70e58c55080a0beb227a
https://doi.org/10.1158/1535-7163.22485185
https://doi.org/10.1158/1535-7163.22485185
Autor:
Frank E. Jones, Edi Brogi, Samuel M. Lesko, Jenny G. Parvani, Tamika T. Duplessis, Yun Zhu, Stella U. Okamgba, Michael J. Brumlik, Doyel Mitra
Supplementary Table 1. Clinical characteristics of 85 primary breast tumors used for statistical analysis; Supplementary Table 2. HER2 and HER2�16 coexpression compared clinicopathological parameters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b968296ce569d6cb04cb32432d8bbf
https://doi.org/10.1158/1535-7163.22485182
https://doi.org/10.1158/1535-7163.22485182
Autor:
Jenny G. Parvani, Gangarao Davuluri, Michael K. Wendt, Christine Espinosa, Maozhen Tian, David Danielpour, Khalid Sossey-Alaoui, William P. Schiemann
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 3, Pp 317-328 (2015)
Transforming growth factor–β (TGF-β) functions to suppress tumorigenesis in normal mammary tissues and early-stage breast cancers and, paradoxically, acts to promote the metastasis and chemoresistance in late-stage breast cancers, particularly tr
Externí odkaz:
https://doaj.org/article/fc71e4ecab9a41399bb0ea076e55c862
Autor:
Elham Azizi, Dana Pe'er, Priyanka Shukla, Jenny G. Parvani, Jan Kitajewski, Seoyeon Kim, Jessica Price, Jill K. Slack-Davis, L. A. Naiche
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233962 (2020)
PLoS ONE
PLoS ONE
High grade serous ovarian cancer (HGSC) is the most common and deadly type of ovarian cancer, largely due to difficulties in early diagnosis and rapid metastasis throughout the peritoneal cavity. Previous studies have shown that expression of Notch3
Publikováno v:
Magnetic Resonance in Medicine. 79:3135-3143
PURPOSE Non-invasive early accurate detection of malignant breast cancer is paramount to the clinical management of the life-threatening disease. Here, we aim to test a small peptide targeted MRI contrast agent, ZD2-Gd(HP-DO3A), specific to an oncopr
Autor:
Jenny G. Parvani, Mark W. Jackson
Publikováno v:
Endocrine-Related Cancer. 24:R81-R97
Over the past decade, RNA interference (RNAi) has been ubiquitously utilized to study biological functionin vitro; however, limitations were associated with its utilityin vivo. More recently, small interfering RNA (siRNA) nanoparticles with improved
Publikováno v:
The Journal of Pathology. 245:6-8
Deciphering the complex milieu that makes up the tumor microenvironment (TME) and the signaling engaged by TME cytokines continues to provide novel targets for therapeutic intervention. The IL-6 family member oncostatin M (OSM) has recently emerged a
Autor:
Hyeon Joo Cheon, Mary R. Doherty, Mark W. Jackson, Benjamin L. Bryson, Damian J. Junk, Ilaria Tamagno, Jenny G. Parvani, George R. Stark
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Background Highly aggressive, metastatic and therapeutically resistant triple-negative breast cancers (TNBCs) are often enriched for cancer stem cells (CSC). Cytokines within the breast tumor microenvironment (TME) influence the CSC state by regulati