Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jenny Flygare"'
Autor:
Stefan Almestrand, Xiao Wang, Åsa Jeppsson-Ahlberg, Marcus Nordgren, Jenny Flygare, Birger Christensson, Stephan Rössner, Birgitta Sander
Publikováno v:
PeerJ, Vol 3, p e1056 (2015)
The cannabinoid receptor type 1 (CB1) antagonist rimonabant has been used as treatment for obesity. In addition, anti-proliferative effects on mitogen-activated leukocytes have been demonstrated in vitro. We have previously shown that rimonabant (SR1
Externí odkaz:
https://doaj.org/article/60395bae457d4a6f9e4363c145c15362
Autor:
Eva Kimby, Björn E. Wahlin, Agata M. Wasik, Patrik Andersson, Fang Zong, Lina Nygren, Stefan Almestrand, Jenny Flygare, Stefanie Baumgartner Wennerholm, Birger Christensson, Birgitta Sander, Leonie Saft
Publikováno v:
Oncoscience
The cannabinoid receptors are upregulated in many types of cancers, including mantle cell lymphoma (MCL) and have been suggested to constitute novel therapeutic targets. The expression pattern of the key members of the endocannabinoid system was anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b4d1ef44c52bf4f9a696122ff4fe89
https://doi.org/10.18632/oncoscience.77
https://doi.org/10.18632/oncoscience.77
Autor:
Katarina Hallén Grufman, Vicky Chatzakos, Petra J. de Verdier, Nasrin Bavand-Chobot, Jenny Flygare, Charlotta Ryk, Tomas Thiel, N. Peter Wiklund
Publikováno v:
Cancer Letters. 348:119-125
The anti-tumour mechanisms following Bacillus Calmette-Guérin (BCG) treatment of bladder-cancer remain largely unknown. Previous studies have shown involvement of nitric-oxide (NO) formation in the BCG-mediated effect. We analyzed the effects of mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a427ad2f8d5d669bcd5199ddfc443330
https://doi.org/10.1016/j.canlet.2014.03.014
https://doi.org/10.1016/j.canlet.2014.03.014
Autor:
Birgitta Sander, A. Charlotta Asplund, Anna Porwit, Birger Christensson, Jenny Flygare, C. I. Edvard Smith, Xiao Wang
Publikováno v:
British Journal of Haematology. 143:248-252
Summary Gene expression analysis demonstrated high expression of the neuronal transcription factor SOX11 in mantle cell lymphoma (MCL). In contrast to follicular lymphoma, small lymphocytic lymphoma and reactive lymphoid tissue, most MCLs tested (48/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed433424947cf36b120ce6b777c7dd0
https://doi.org/10.1111/j.1365-2141.2008.07329.x
https://doi.org/10.1111/j.1365-2141.2008.07329.x
Publikováno v:
Pharmacology Research & Perspectives
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. The multityrosine kinase inhibitor sorafenib is used in the therapy of advanced disease. However, the effects of sorafenib are limited, and combination tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10edaaf6a68299e60a2bc03709b1cd59
https://doi.org/10.1002/prp2.171
https://doi.org/10.1002/prp2.171
Autor:
Marcus Nordgren, Xiao Wang, Åsa Jeppsson-Ahlberg, Stefan Almestrand, Birger Christensson, Stephan Rössner, Birgitta Sander, Jenny Flygare
Publikováno v:
PeerJ, Vol 3, p e1056 (2015)
PeerJ
PeerJ
The cannabinoid receptor type 1 (CB1) antagonist rimonabant has been used as treatment for obesity. In addition, anti-proliferative effects on mitogen-activated leukocytes have been demonstrated in vitro. We have previously shown that rimonabant (SR1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1e43f06756cec57559008d6d5176ac
https://peerj.com/articles/1056.pdf
https://peerj.com/articles/1056.pdf
Publikováno v:
FEBS Letters. 579:6885-6889
We have earlier reported overexpression of the central and peripheral cannabinoid receptors CB1 and CB2 in mantle cell lymphoma (MCL), a B cell non-Hodgkin lymphoma. In this study, treatment with cannabinoid receptor ligands caused a decrease in viab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0623acb5b1fd30073aba204604ee0e
https://doi.org/10.1016/j.febslet.2005.11.020
https://doi.org/10.1016/j.febslet.2005.11.020
Autor:
Johan Lidén, Birger Christensson, C. I. Edvard Smith, Eva Kimby, Emma K. Emanuelsson, Birgitta Sander, Anna Porwit-MacDonald, Jenny Flygare
Publikováno v:
International Journal of Cancer. 117:418-430
The role of transcript variants of cyclin D1 in cancer biology is unclear. Most tumors with high levels of cyclin D1 express 2 transcripts due to alternative splicing: one full-length transcript of 4.4 kb and one short transcript of approximately 1.7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9360553e0c7955abc41171402d1dee9c
https://doi.org/10.1002/ijc.21166
https://doi.org/10.1002/ijc.21166
Publikováno v:
European Journal of Biochemistry. 267:5977-5982
The human recombinase HsRad51 is cleaved during apoptosis. We have earlier observed cleavage of the 41-kDa full-length protein into a 33-kDa product in apoptotic Jurkat cells and in in vitro translated HsRad51 after treatment with activated S-100 ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7bd37dcfcc2bbdd7b6b24e633d1d064
https://doi.org/10.1046/j.1432-1327.2000.01675.x
https://doi.org/10.1046/j.1432-1327.2000.01675.x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1312(3):231-236
The S. cerevisiae RAD51 gene product exerts important functions in meiotic and mitotic recombination, as well as in the repair of DNA double-strand breaks. We have studied the expression of the human RAD51 (HsRAD51) gene in primary human peripheral b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9004088bf51f3b344a5caa55a62e1e2d