Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jenny F. Nathans"'
Autor:
Sang-Min Jang, Jenny F. Nathans, Haiqing Fu, Christophe E. Redon, Lisa M. Jenkins, Bhushan L. Thakur, Lőrinc S. Pongor, Adrian M. Baris, Jacob M. Gross, Maura J. OʹNeill, Fred E. Indig, Steven D. Cappell, Mirit I. Aladjem
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The spindle assembly checkpoint (SAC) safeguards chromosome segregation by regulating the anaphase promoting complex/cyclosome (APC/C), allowing chromosomes to correctly attach to mitotic spindles. Here the authors reveal a role for Cullin–RING ubi
Externí odkaz:
https://doaj.org/article/acb64edefaf545c091ce4db99899a6a3
Autor:
Xiaoyi Li, Wei Chen, Beth K. Martin, Diego Calderon, Choli Lee, Junhong Choi, Florence M. Chardon, Troy McDiarmid, Haedong Kim, Jean-Benoît Lalanne, Jenny F. Nathans, Jay Shendure
Publikováno v:
bioRxiv
Prime editing is a powerful means of introducing precise changes to specific locations in mammalian genomes. However, the widely varying efficiency of prime editing across target sites of interest has limited its adoption in the context of both basic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c905bcb9d87e0305187017c68bc9730
https://europepmc.org/articles/PMC10120711/
https://europepmc.org/articles/PMC10120711/
Publikováno v:
Science Advances
Cells advance through G1 phase for 2 hours after DNA damage, and if not stopped in time, they will enter S phase with damaged DNA.
The G1-S checkpoint is thought to prevent cells with damaged DNA from entering S phase and replicating their DNA a
The G1-S checkpoint is thought to prevent cells with damaged DNA from entering S phase and replicating their DNA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f570aa9f2bf2a994e0d415532f71b747
http://europepmc.org/articles/PMC7806216
http://europepmc.org/articles/PMC7806216
Autor:
Mirit I. Aladjem, Maura J. OʹNeill, Jacob M. Gross, Jenny F. Nathans, Lőrinc S. Pongor, Sang-Min Jang, Lisa M. Miller Jenkins, Christophe E. Redon, Haiqing Fu, Fred E. Indig, Steven D. Cappell, Adrian Baris, Bhushan Thakur
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The spindle assembly checkpoint (SAC) prevents premature chromosome segregation by inactivating the anaphase promoting complex/cyclosome (APC/C) until all chromosomes are properly attached to mitotic spindles. Here we identify a role for Cullin–RIN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a17dbac0aab6849700eacb0fdce646
http://europepmc.org/articles/PMC6946706
http://europepmc.org/articles/PMC6946706
Autor:
Therese A. Yario, Reut Shalgi, Niv Sabath, Yuval Wiesel, Joan A. Steitz, Jenny F. Nathans, Anna Vilborg, Flonia Levy-Adam
Publikováno v:
Proceedings of the National Academy of Sciences
Transcription is a highly regulated process, and stress-induced changes in gene transcription have been shown to play a major role in stress responses and adaptation. Genome-wide studies reveal prevalent transcription beyond known protein-coding gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff07d908cdb96f76943ef0d110dc2448