Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jenny Eichhorst"'
Autor:
Hannes Gonschior, Christopher Schmied, Rozemarijn Eva Van der Veen, Jenny Eichhorst, Nina Himmerkus, Jörg Piontek, Dorothee Günzel, Markus Bleich, Mikio Furuse, Volker Haucke, Martin Lehmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Meshworks of claudin polymers control the paracellular transport and barrier properties of epithelial tight junctions. Here, the authors show different claudin nanoscale organization principles, finding that claudin segregation enables barrier format
Externí odkaz:
https://doaj.org/article/e06a6dbe34ce4a00a20dfb452d7088e7
Autor:
Sandrine Baltzer, Timur Bulatov, Christopher Schmied, Andreas Krämer, Benedict-Tilman Berger, Andreas Oder, Ryan Walker-Gray, Christin Kuschke, Kerstin Zühlke, Jenny Eichhorst, Martin Lehmann, Stefan Knapp, John Weston, Jens Peter von Kries, Roderich D. Süssmuth, Enno Klussmann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 763 (2022)
The cAMP-dependent aquaporin-2 (AQP2) redistribution from intracellular vesicles into the plasma membrane of renal collecting duct principal cells induces water reabsorption and fine-tunes body water homeostasis. However, the mechanisms controlling t
Externí odkaz:
https://doaj.org/article/be752154d8be482f938e4f7c5fb62df4
Autor:
Alessandro Dema, Dörte Faust, Katina Lazarow, Marc Wippich, Martin Neuenschwander, Kerstin Zühlke, Andrea Geelhaar, Tamara Pallien, Eileen Hallscheidt, Jenny Eichhorst, Burkhard Wiesner, Hana Černecká, Oliver Popp, Philipp Mertins, Gunnar Dittmar, Jens Peter von Kries, Enno Klussmann
Publikováno v:
Cells, Vol 9, Iss 3, p 673 (2020)
Arginine-vasopressin (AVP) facilitates water reabsorption in renal collecting duct principal cells through regulation of the water channel aquaporin-2 (AQP2). The hormone binds to vasopressin V2 receptors (V2R) on the surface of the cells and stimula
Externí odkaz:
https://doaj.org/article/2e53df9d47594aa78197c2dae41ffcc8
Autor:
Katharina Schrade, Jessica Tröger, Adeeb Eldahshan, Kerstin Zühlke, Kamal R Abdul Azeez, Jonathan M Elkins, Martin Neuenschwander, Andreas Oder, Mohamed Elkewedi, Sarah Jaksch, Karsten Andrae, Jinliang Li, Joao Fernandes, Paul Markus Müller, Stephan Grunwald, Stephen F Marino, Tanja Vukićević, Jenny Eichhorst, Burkhard Wiesner, Marcus Weber, Michael Kapiloff, Oliver Rocks, Oliver Daumke, Thomas Wieland, Stefan Knapp, Jens Peter von Kries, Enno Klussmann
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191423 (2018)
Stimulation of renal collecting duct principal cells with antidiuretic hormone (arginine-vasopressin, AVP) results in inhibition of the small GTPase RhoA and the enrichment of the water channel aquaporin-2 (AQP2) in the plasma membrane. The membrane
Externí odkaz:
https://doaj.org/article/90f46ed5dd9245e28b25eb7c6c87fe03
Autor:
Roger Gilabert-Oriol, Mayank Thakur, Benedicta von Mallinckrodt, Cheenu Bhargava, Burkhard Wiesner, Jenny Eichhorst, Matthias F. Melzig, Hendrik Fuchs, Alexander Weng
Publikováno v:
Toxins, Vol 6, Iss 5, Pp 1644-1666 (2014)
Protein-based therapeutics with cytosolic targets are capable of exhibiting their therapeutic effect once they have escaped from the endosomes or lysosomes. In this study, the reporters—horseradish peroxidase (HRP), Alexa Fluor 488 (Alexa) and rici
Externí odkaz:
https://doaj.org/article/56e0e86d132a4591bdaf9cfe44c3e733
Autor:
Cécile Otten, Peter F van der Ven, Ilka Lewrenz, Sandeep Paul, Almut Steinhagen, Elisabeth Busch-Nentwich, Jenny Eichhorst, Burkhard Wiesner, Derek Stemple, Uwe Strähle, Dieter O Fürst, Salim Abdelilah-Seyfried
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31041 (2012)
Myocellular regeneration in vertebrates involves the proliferation of activated progenitor or dedifferentiated myogenic cells that have the potential to replenish lost tissue. In comparison little is known about cellular repair mechanisms within myoc
Externí odkaz:
https://doaj.org/article/e3694f189e7645cc911e7d23fd6cfbd1
Autor:
Kilian Roßmann, Kerem C. Akkaya, Pascal Poc, Corentin Charbonnier, Jenny Eichhorst, Hannes Gonschior, Abha Valavalkar, Nicolas Wendler, Thorben Cordes, Benjamin Dietzek-Ivanšić, Ben Jones, Martin Lehmann, Johannes Broichhagen
Publikováno v:
Chemical Science. 13:8605-8617
Deuteration enhances photophysical and chemical properties of fluorescent rhodamine dyes for higher brightness in sensitive microscopy.
Autor:
Maria Ercu, Michael B. Mücke, Tamara Pallien, Lajos Markó, Anastasiia Sholokh, Carolin Schächterle, Atakan Aydin, Alexa Kidd, Stephan Walter, Yasmin Esmati, Brandon J. McMurray, Daniella F. Lato, Daniele Yumi Sunaga-Franze, Philip H. Dierks, Barbara Isabel Montesinos Flores, Ryan Walker-Gray, Maolian Gong, Claudia Merticariu, Kerstin Zühlke, Michael Russwurm, Tiannan Liu, Theda U.P. Batolomaeus, Sabine Pautz, Stefanie Schelenz, Martin Taube, Hanna Napieczynska, Arnd Heuser, Jenny Eichhorst, Martin Lehmann, Duncan C. Miller, Sebastian Diecke, Fatimunnisa Qadri, Elena Popova, Reika Langanki, Matthew A. Movsesian, Friedrich W. Herberg, Sofia K. Forslund, Dominik N. Müller, Tatiana Borodina, Philipp G. Maass, Sylvia Bähring, Norbert Hübner, Michael Bader, Enno Klussmann
Publikováno v:
Circulation. 146(23)
Background: Phosphodiesterase 3A ( PDE3A ) gain-of-function mutations cause hypertension with brachydactyly (HTNB) and lead to stroke. Increased peripheral vascular resistance, rather than salt retention, is responsible. It is surprising that the few
Autor:
Fatimunnisa Qadri, Russell Hodge, Kerstin Zühlke, Yoland-Marie Anistan, Martin Lehmann, Dmitry Tsvetkov, Lajos Markó, Sara Maghsodi, Astrid Mühl, Michael Russwurm, Atakan Aydin, Rosana Molé Illas, Mihail Todiras, Burkhard Wiesner, Carolin Schächterle, Elena Popova, Maria Ercu, Ilona Kamer, Martin Taube, Enno Klussmann, Jenny Eichhorst, Sofia K. Forslund, Arnd Heuser, Nerine Gregersen, Michael Bader, Stefanie Schelenz, Norbert Hubner, Stephan Walter, Philipp G. Maass, Ralph Plehm, Theda U P Bartolomaeus, Yingqiu Cui, Reika Langanki, Bärbel Pohl, Andrea Geelhaar, Hanna Napieczynska, Sylvia Bähring, Friedrich C. Luft, Dominik N. Müller, Maik Gollasch
Publikováno v:
Circulation. 142:133-149
Background: High blood pressure is the primary risk factor for cardiovascular death worldwide. Autosomal dominant hypertension with brachydactyly clinically resembles salt-resistant essential hypertension and causes death by stroke before 50 years of
Autor:
Hannes Gonschior, Christopher Schmied, Rozemarijn Eva Van der Veen, Jenny Eichhorst, Nina Himmerkus, Jörg Piontek, Dorothee Günzel, Markus Bleich, Mikio Furuse, Volker Haucke, Martin Lehmann
Publikováno v:
Nature communications. 13(1)
The paracellular passage of ions and small molecules across epithelia is controlled by tight junctions, complex meshworks of claudin polymers that form tight seals between neighboring cells. How the nanoscale architecture of tight junction meshworks