Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jenny D.Y. Chow"'
Autor:
Kyle L. Hoehn, Jill K. Slack-Davis, Kodi S. Ravichandran, Kelle H. Moley, Douglas C. Marchion, Johnathan M. Lancaster, Kristen A. Atkins, William D. Baker, Marin E. Healy, Jenny D.Y. Chow, Jose L. Tomsig, Susan C. Modesitt, Ivan K.H. Poon, Frances L. Byrne
Supplemental Figures S1-8. Figure S1: Protein expression in human endometrial tissue. Figure S2: GLUT6 expression in human endometrial tissue Figure S3: Correlation between metabolic protein expression and metabolism in endometrial cells. Figure S4:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c139e0ded6899be6b48e214b54dc3a
https://doi.org/10.1158/0008-5472.22402731
https://doi.org/10.1158/0008-5472.22402731
Autor:
Kyle L. Hoehn, Jill K. Slack-Davis, Kodi S. Ravichandran, Kelle H. Moley, Douglas C. Marchion, Johnathan M. Lancaster, Kristen A. Atkins, William D. Baker, Marin E. Healy, Jenny D.Y. Chow, Jose L. Tomsig, Susan C. Modesitt, Ivan K.H. Poon, Frances L. Byrne
Supplemental Methods. Includes more detailed methods for the main manuscript and additional supplemental methods including Cell Culture, Sources of drugs/radioactive tracers,Targets/functions of metabolic drugs and antioxidants, Preparation of protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db771c57c8de0d80e626cc822c8590d4
https://doi.org/10.1158/0008-5472.22402728.v1
https://doi.org/10.1158/0008-5472.22402728.v1
Autor:
Mark D. Hulett, Christina Nedeva, Bo Shi, Ivan K. H. Poon, Jenny D.Y. Chow, Thanh Kha Phan, Hamsa Puthalakath, Georgia K. Atkin-Smith, Marco J Herold, Sarah Caruso, Rochelle Tixeira
Publikováno v:
Cell Death Differ
Many cell types are known to undergo a series of morphological changes during the progression of apoptosis, leading to their disassembly into smaller membrane-bound vesicles known as apoptotic bodies (ApoBDs). In particular, the formation of circular
Autor:
Mark D. Hulett, Georgia K. Atkin-Smith, Stephanie Paone, Bo Shi, Thanh Kha Phan, Amy L. Hodge, Christopher D. Gregory, Jascinta P Santavanond, Rochelle Tixeira, Ivan K. H. Poon, Lanzhou Jiang, Amy A. Baxter, Stephanie F. Rutter, Michael A. F. Parkes, Sarah Caruso, Dilara Ceyda Ozkocak, Jenny D.Y. Chow
Publikováno v:
Poon, I K H, Parkes, M A F, Jiang, L, Atkin-smith, G K, Tixeira, R, Gregory, C D, Ozkocak, D C, Rutter, S F, Caruso, S, Santavanond, J P, Paone, S, Shi, B, Hodge, A L, Hulett, M D, Chow, J D Y, Phan, T K & Baxter, A A 2019, ' Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles in vitro ', Journal of Extracellular Vesicles, vol. 8, no. 1, pp. 1608786 . https://doi.org/10.1080/20013078.2019.1608786
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Apoptosis is a form of programmed cell death that occurs throughout life as part of normal development as well as pathologic processes including chronic inflammation and infection. Although the death of a cell is often considered as the only biologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f5efc2d41f873102aec2f6423dcee3
https://hdl.handle.net/20.500.11820/e99214a5-3585-47d0-ac4e-46e91cac31ef
https://hdl.handle.net/20.500.11820/e99214a5-3585-47d0-ac4e-46e91cac31ef
Autor:
Carolin Lackner, Jenny D.Y. Chow, David S. Breen, Chien Li, Norbert Leitinger, Frances L. Byrne, Stephen H. Caldwell, Marin E. Healy, Kyle L. Hoehn
Publikováno v:
Journal of Hepatology. 62:599-606
Background & Aims Mice exposed to the hepatocellular carcinogen diethylnitrosamine at 2weeks of age have a high risk of developing primary liver tumors later in life. Previous studies have demonstrated that diethylnitrosamine-treated mice have increa
Autor:
Nigel Turner, Marin E. Nelson, Lindsay E. Wu, Ellen M. Olzomer, Stephen H. Caldwell, Carolin Lackner, David S. Breen, Jenny D.Y. Chow, Kyle L. Hoehn, Stefan R. Hargett, Gregory J. Cooney, Sujoy Lahiri, Frances L. Byrne, Jill K. Slack-Davis, David E. James
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Nature Communications
The metabolic pathway of de novo lipogenesis is frequently upregulated in human liver tumours, and its upregulation is associated with poor prognosis. Blocking lipogenesis in cultured liver cancer cells is sufficient to decrease cell viability; howev
Autor:
Kyle L. Hoehn, W. Baker, Jenny D.Y. Chow, Kristen A. Atkins, Johnathan M. Lancaster, Susan C. Modesitt, Jose L. Tomsig, Kelle H. Moley, Douglas C. Marchion, Ivan K. H. Poon, Kodi S. Ravichandran, Frances L. Byrne, Jill K. Slack-Davis, Marin E. Healy
Publikováno v:
Cancer Research. 74:5832-5845
Women with metabolic disorders, including obesity and diabetes, have an increased risk of developing endometrial cancer. However, the metabolism of endometrial tumors themselves has been largely understudied. Comparing human endometrial tumors and ce
Autor:
Kyle L. Hoehn, Brandon M. Kenwood, Valeria R. Mas, Robert T. Lawrence, David S. Breen, Frances L. Byrne, Gregory J. Cooney, Pere Puigserver, David E. James, Stephen H. Caldwell, Jenny D.Y. Chow, Jason A. Liao, Carolin Lackner, Saeko Okutsu, Jose L. Tomsig, John E. Dominy, Marin E. Healy, Nigel Turner, Judit Villén
Publikováno v:
Molecular Metabolism
Lipid deposition in the liver is associated with metabolic disorders including fatty liver disease, type II diabetes, and hepatocellular cancer. The enzymes acetyl-CoA carboxylase 1 (ACC1) and ACC2 are powerful regulators of hepatic fat storage; ther
Autor:
Jenny D.Y. Chow, Mark J. Smyth, Katharine J. Goodall, Catherine Horan, Mark D. Hulett, Eloisa Pagler, Gemma F. Ryan, Klaus I. Matthaei, Michael K. L. Wong, Daniel M. Andrews, Carly L. Conlan, Simon Phipps, Ivan K. H. Poon, Julie White
Publikováno v:
European Journal of Immunology. 44:1016-1030
Heparanase is a β-d-endoglucuronidase that cleaves heparan sulphate, a key component of the ECM and basement membrane. The remodelling of the ECM by heparanase has been proposed to regulate both normal physiological and pathological processes, inclu
Autor:
Carolin Lackner, Frances L. Byrne, Jenny D.Y. Chow, Kyle L. Hoehn, David S. Breen, Brandon M. Kenwood, Stefan R. Hargett, Marin E. Healy, Evan P. Taddeo, Sujoy Lahiri, Stephen H. Caldwell
Publikováno v:
Scientific Reports
Overnutrition can promote liver cancer in mice and humans that have liver damage caused by alcohol, viruses, or carcinogens. However, the mechanism linking diet to increased liver tumorigenesis remains unclear in the context of whether tumorigenesis