Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jenny D. Jokinen"'
Autor:
Dylan M. Johnson, Nittaya Khakhum, Min Wang, Nikole L. Warner, Jenny D. Jokinen, Jason E. Comer, Igor S. Lukashevich
Publikováno v:
Viruses, Vol 16, Iss 4, p 635 (2024)
Lymphocytic choriomeningitis virus (LCMV) and Lassa virus (LASV) share many genetic and biological features including subtle differences between pathogenic and apathogenic strains. Despite remarkable genetic similarity, the viscerotropic WE strain of
Externí odkaz:
https://doaj.org/article/5275071d108a4037a2a24aed3c7d763c
Autor:
Dylan M. Johnson, Kevin J. Sokoloski, Jenny D. Jokinen, Tia L. Pfeffer, Yong-Kyu Chu, Robert S. Adcock, Donghoon Chung, Irina Tretyakova, Peter Pushko, Igor S. Lukashevich
Publikováno v:
Vaccines, Vol 8, Iss 1, p 114 (2020)
The safety and genetic stability of V4020, a novel Venezuelan Equine Encephalitis Virus (VEEV) vaccine based on the investigational VEEV TC-83 strain, was evaluated in mice. V4020 was generated from infectious DNA, contains a stabilizing mutation in
Externí odkaz:
https://doaj.org/article/15827f979e554e8cabf0efcfc4a517ca
Publikováno v:
Pathogens, Vol 8, Iss 1, p 9 (2019)
Lassa virus (LASV), a highly prevalent mammalian arenavirus endemic in West Africa, can cause Lassa fever (LF), which is responsible for thousands of deaths annually. LASV is transmitted to humans from naturally infected rodents. At present, there is
Externí odkaz:
https://doaj.org/article/b6f94d46716d406e9da6d378a295a24c
Autor:
Juliane I Beier, Jenny D Jokinen, Gretchen E Holz, Patrick S Whang, Amah M Martin, Nikole L Warner, Gavin E Arteel, Igor S Lukashevich
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122839 (2015)
Viral hemorrhagic fevers (VHFs) encompass a group of diseases with cardinal symptoms of fever, hemorrhage, and shock. The liver is a critical mediator of VHF disease pathogenesis and high levels of ALT/AST transaminases in plasma correlate with poor
Externí odkaz:
https://doaj.org/article/fd2efc4a1c6e46fb854d187a7373d291
Autor:
Irina Tretyakova, Dylan M. Johnson, Igor S. Lukashevich, Jenny D. Jokinen, Alexander Tibbens, Peter Pushko
Publikováno v:
Vaccine. 37:3317-3325
Novel live-attenuated V4020 vaccine was prepared for Venezuelan equine encephalitis virus (VEEV), an alphavirus from the Togaviridae family. The genome of V4020 virus was rearranged, with the capsid gene expressed using a duplicate subgenomic promote
Autor:
Igor S. Lukashevich, Peter Pushko, Kevin J. Sokoloski, Jenny D. Jokinen, Tia L. Pfeffer, Irina Tretyakova, Dylan M. Johnson, Yong Kyu Chu, Donghoon Chung, Robert S. Adcock
Publikováno v:
Vaccines, Vol 8, Iss 1, p 114 (2020)
Vaccines
Volume 8
Issue 1
Vaccines
Volume 8
Issue 1
The safety and genetic stability of V4020, a novel Venezuelan Equine Encephalitis Virus (VEEV) vaccine based on the investigational VEEV TC-83 strain, was evaluated in mice. V4020 was generated from infectious DNA, contains a stabilizing mutation in
Autor:
Igor S. Lukashevich, Dylan M. Johnson, Jenny D. Jokinen, Min Wang, Anthony Griffiths, Irina Tretyakova, Tia L. Pfeffer, Peter Pushko, Ricardo Carrion
Publikováno v:
Vaccine
Junin (JUNV) and Machupo (MACV), two mammalian arenaviruses placed on the 2018 WHO watch list, are prevalent in South America causing Argentine and Bolivian hemorrhagic fevers (AHF and BHF), respectively. The live attenuated JUNV vaccine, Candid #1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227a499ff71855459b5cf2e21beca356
https://europepmc.org/articles/PMC7112472/
https://europepmc.org/articles/PMC7112472/
Publikováno v:
Vaccine
Lassa virus (LASV) is the most prevalent rodent-borne arenavirus circulated in West Africa. With population at risk from Senegal to Nigeria, LASV causes Lassa fever and is responsible for thousands of deaths annually. High genetic diversity of LASV i
Publikováno v:
Pathogens
Volume 8
Issue 1
Pathogens, Vol 8, Iss 1, p 9 (2019)
Volume 8
Issue 1
Pathogens, Vol 8, Iss 1, p 9 (2019)
Lassa virus (LASV), a highly prevalent mammalian arenavirus endemic in West Africa, can cause Lassa fever (LF), which is responsible for thousands of deaths annually. LASV is transmitted to humans from naturally infected rodents. At present, there is
Autor:
Igor S. Lukashevich, Kevin J. Sokoloski, Jenny D. Jokinen, Juliane I. Beier, Nikole L. Warner
Publikováno v:
Viruses
Viruses; Volume 10; Issue 2; Pages: 75
Viruses; Volume 10; Issue 2; Pages: 75
Mammarenavirusesare single-stranded RNA viruses with a bisegmented ambisense genome. Ingestion has been shown as a natural route of transmission for both Lassa virus (LASV) and Lymphocytic choriomeningitis virus (LCMV). Due to the mechanism of transm