Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jenny Cromsigt"'
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 19:627-636
Hepatitis B virus (HBV) HBV is DNA virus with a unique replication strategy, which involves reverse transcription of its pregenomic RNA. Essential for this reverse transcription are the 5'- and 3'-ends of its pregenomic RNA (5'-RT-RNA and 3'-RT-RNA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6140e0b10ca0f1a006c084bbbf4361
https://doi.org/10.1080/07391102.2002.10506769
https://doi.org/10.1080/07391102.2002.10506769
Publikováno v:
Journal of Biomolecular NMR. 21:11-29
An analysis is presented of experimental versus calculated chemical shifts of the non-exchangeable protons for 28 RNA structures deposited in the Protein Data Bank, covering a wide range of structural building blocks. We have used existing models for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbfb9fe16fab2ae44bc3d9110d8a7593
https://doi.org/10.1023/a:1011914132531
https://doi.org/10.1023/a:1011914132531
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 17:211-219
We propose a strategy for NMR structure determination of RNA based on deuteration and use of specific labeling patterns. This strategy involves the use of NTPs that are deuterated in the ribose ring except for specific positions, e.g. H2', and that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b076a9ec57dc351b80e1b36ea256ce3
https://doi.org/10.1080/07391102.2000.10506624
https://doi.org/10.1080/07391102.2000.10506624
An effective in vitro enzymatic synthesis is described for the production of nucleoside triphosphates (NTPs) which are stereo-specifically deuterated on the H5" position with high selectivity (98%), and which can have a variety of different labels (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3726ebb6302bb8039409fed97fdf1468
https://europepmc.org/articles/PMC101849/
https://europepmc.org/articles/PMC101849/
Autor:
Sara Flodell, Hans Ippel, Jenny Cromsigt, Sybren S. Wijmenga, Jürgen Schleucher, Karin Kidd-Ljunggren
Publikováno v:
Nucleic Acids Research, 30, 4803-4811
Nucleic Acids Research, 30, 21, pp. 4803-4811
Nucleic Acids Research, 30, 21, pp. 4803-4811
Reverse transcription of hepatitis B virus (HBV) pregenomic RNA is essential for virus replication. In the first step of this process, HBV reverse transcriptase binds to the highly conserved encapsidation signal, epsilon (epsilon), situated near the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6d560c297f58dbdcee94e069229e88
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/79478
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/79478
Structural and functional importance of mutations in Hepatitis B virus pregenomic RNA studied by NMR
Publikováno v:
Biochemical Society Transactions. 28:A446-A446
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1651cbdd95c10095cc35e7cd25caa86
https://doi.org/10.1042/bst028a446a
https://doi.org/10.1042/bst028a446a