Výsledky vyhledávání - "Jenny C. Luxton"

HPV16 E6 oncogene variants in women with cervical intraepithelial neoplasia

Autor: John Cason, Rahul Nath, Nawal Derias, Jenny C. Luxton, Benjamin Greenwood, Philip S. Shepherd, Christine Mant

Publikováno v: Journal of Medical Virology. 60:337-341

Human papillomaviruses (HPVs) are strongly associated with the development of high grade cervical intraepithelial neoplasia (CIN) and cervical carcinoma, with between 40-80% of patients with cervical carcinoma being attributed to a single HPV type, H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ddde0fd2704393d8af2c250ac49397
https://doi.org/10.1002/(sici)1096-9071(200003)60:3<337::aid-jmv13>3.0.co

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Serological and T-helper cell responses to human papillomavirus type 16 L1 in women with cervical dysplasia or cervical carcinoma and in healthy controls

Autor: Philip Wilson, R C Rose, Philip S. Shepherd, Jenny C. Luxton, Timothy Coletart

Publikováno v: Journal of General Virology. 78:917-923

In a cross-sectional study we have investigated serological and T-helper (Th) cell responses to human papillomavirus type 16 (HPV-16) L1 in women with HPV-16 related diseases and related them to cervical histology and HPV DNA status. Using a virus-li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76625d4cd0cee3072adc7d4fe0898d13
https://doi.org/10.1099/0022-1317-78-4-917

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Proliferative T cell responses to the human papillomavirus type 16 E7 protein in women with cervical dysplasia and cervical carcinoma and in healthy individuals

Autor: Jenny C. Luxton, Philip Wilson, Philip S. Shepherd, Timothy Coletart, Jeremy C. Cridland, Andrea J. Rowe

Publikováno v: Journal of General Virology. 77:1585-1593

The levels of proliferative T cell responses to peptides representing the human papillomavirus type 16 (HPV-16) E7 protein have been measured using short-term T cell lines derived from peripheral blood of healthy women and those with cervical dysplas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b27580b9132ec810ad384496f28b0b57
https://doi.org/10.1099/0022-1317-77-7-1585

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Human papillomavirus type 16-specific T cell responses and their association with recurrence of cervical disease following treatment

Autor: Nawal Derias, Rahul Nath, Jenny C. Luxton, Amanda Herbert, Philip S. Shepherd

Publikováno v: The Journal of general virology. 84(Pt 5)

Human papillomavirus type 16 (HPV-16) L1- and E7-specific T cell responses were measured in 58 women with abnormal cervical cytology in a prospective study. On recruitment, patients responded most frequently and with the highest numbers of responding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c22a4ca6d753a89a0b295a9348af8d5
https://pubmed.ncbi.nlm.nih.gov/12692269

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Human papillomavirus antigens and T-cell recognition

Autor: Philip S. Shepherd, Jenny C. Luxton

Publikováno v: Current opinion in infectious diseases. 14(2)

This review will summarize what is known about natural T-cell responses to human papillomavirus infections, including potential mechanisms for their dysregulation which may lead to the development of disease. We will also describe new strategies to e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1210563f877d4bde19460e6918259c31
https://pubmed.ncbi.nlm.nih.gov/11979123

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Proliferative T cell responses to human papillomavirus type 16 L1 peptides in patients with cervical dysplasia

Autor: Philip Wilson, Timothy Coletart, Jeremy C. Cridland, Andrea J. Rowe, Jenny C. Luxton, Philip S. Shepherd

Publikováno v: The Journal of general virology. 77

Human papillomavirus type 16 (HPV-16) can cause genital warts, cervical dysplasias and carcinoma of the cervix. Cell-mediated immunity is thought to be important in protection against the virus and in its elimination, but little is known about the me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6a79884c03eacffdc28237281405ed
https://pubmed.ncbi.nlm.nih.gov/8627247

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An Immunodominant Region in HPV16.L1 Identified by T Cell Responses in Patients with Cervical Dysplasias

Autor: Lee S. Rayfield, Jeremy C. Cridland, Andrea J. Rowe, Philip S. Shepherd, Michael Chapman, Jenny C. Luxton

Publikováno v: Immunology of Human Papillomaviruses ISBN: 9781461360414

Human papillomaviruses are truly epitheliotropic and give rise to skin and mucosal. lesions. How the host controls and eliminates HPV infections at these surfaces remains largely unknown. In the genital. tract HPV has been shown to cause genital. war

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4bc3cd4f5516bce8427cba95c803f8e
https://doi.org/10.1007/978-1-4615-2449-6_37

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Epstein-Barr virus infection of HIV-seropositive individuals is transiently suppressed by high-dose acyclovir treatment

Autor: Dorothy H. Crawford, Ian S. Williams, Ian V. D. Weller, Jenny C. Luxton

Publikováno v: AIDS (London, England). 7(10)

Objective To assess whether oral acyclovir can eliminate persistent Epstein-Barr virus (EBV) infection and thereby prevent EBV-associated lymphoma development in HIV-seropositive homosexual men. Method Persistent EBV infection was examined in a group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f18968d6d9abfbd5bb030316dff56e
https://pubmed.ncbi.nlm.nih.gov/8267906

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