Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jenny C Karlsson"'
Publikováno v:
The Journal of Pathology
The lung is composed of airways and lung parenchyma, and the extracellular matrix (ECM) contains the main building blocks of both components. The ECM provides physical support and stability to the lung, and as such it has in the past been regarded as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9e057d78c93d0db2f4492ae61357fd
https://doi.org/10.1002/path.4808
https://doi.org/10.1002/path.4808
ROS-induced endothelial stress contributes to pulmonary fibrosis through pericytes and Wnt signaling
Publikováno v:
Laboratory Investigation. 96:206-217
Pulmonary fibrosis is a grave diagnosis with insidious progression, generally considered as a consequence of aberrant epithelial wound healing and excessive scarring. This process is commonly modeled in animals by local bleomycin administration, resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278da31aabd294ce381159994807572b
https://doi.org/10.1038/labinvest.2015.100
https://doi.org/10.1038/labinvest.2015.100
Autor:
Margarete Mehrabian, Sana Majid, Aldons J. Lusis, Tao Xie, Pek Yee Lum, Daria Estrada-Smith, Lawrence W. Castellani, Thomas A. Drake, Robert R. Kleinhanz, Anatole Ghazalpour, Gevork Torosyan, Jun Zhu, Joshua L. Deignan, Eric E. Schadt, Su Qian, Kai Wang, Katrina M. Dipple, Jenny C Karlsson, Douglas J. MacNeil, Xia Yang, Judy Zhong, Charles R. Farber, Marc L. Reitman, Bin Zhang, Michael Coon, Chunsheng Zhang, Susanna S. Wang, John Lamb, Hongxiu Qi, Sheena Mumick, Atila van Nas, Brie Falkard
Publikováno v:
Nature genetics, vol 41, iss 4
A principal task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a8962f681de249ed5b3c77814e0b6e
https://doi.org/10.1038/ng.325
https://doi.org/10.1038/ng.325
Autor:
Anna-Karin Larsson-Callerfelt, Sara Rolandsson, Oskar Hallgren, Jenny C Karlsson, Emil Tykesson, Kristina Rydell-Törmänen, Gunilla Westergren-Thorsson, Anders Malmström, Maria Weitoft, Leif Bjermer, Annika Andersson-Sjöland
Publikováno v:
Glycobiology; 25(3), pp 243-251 (2015)
Glycobiology
Glycobiology
Versican is a proteoglycan that has many different roles in tissue homeostasis and inflammation. The biochemical structure is comprised of four different types of the core protein with attached glycosaminoglycans that can be sulphated to various exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdcacbb945e951bc99206531d1912b8
https://lup.lub.lu.se/record/4820224
https://lup.lub.lu.se/record/4820224
Autor:
Andrew D. Cook, Lina Olsson, Patrik Wernhoff, Åsa Andersson, Jenny C Karlsson, Anna-Karin B. Lindqvist, Kutty Selva Nandakumar, Rikard Holmdahl, Martina Johannesson
Publikováno v:
Genes & Immunity. 6:175-185
Identification of genes controlling complex diseases has proven to be difficult; however, animal models may pave the way to determine how low penetrant genes interact to promote disease development. We have dissected the Cia5/Eae3 susceptibility locu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca004174188a9fd171a472e645b3bdd
https://doi.org/10.1038/sj.gene.6364155
https://doi.org/10.1038/sj.gene.6364155
Autor:
Jenny C Karlsson, Åsa Andersson, Therese Lindvall, Rikard Holmdahl, Martina Johannesson, Patrik Wernhoff
Publikováno v:
The Journal of Immunology. 174:533-541
The Eae2 locus on mouse chromosome 15 controls the development of experimental autoimmune encephalomyelitis (EAE); however, in this study we show that it also controls collagen-induced arthritis (CIA). To find the smallest disease-controlling locus/l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd84145102df8ce1be230fba434dab78
https://doi.org/10.4049/jimmunol.174.1.533
https://doi.org/10.4049/jimmunol.174.1.533
Autor:
Jenny C Karlsson, Åsa Andersson, Xiangshan Zhao, Irina Lonskaya, Rikard Holmdahl, Malin Neptin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 170(2)
The B10.RIII mouse strain (H-2r) develops chronic experimental autoimmune encephalomyelitis (EAE) upon immunization with the myelin basic protein 89–101 peptide. EAE was induced and studied in a backcross between B10.RIII and the EAE-resistant RIII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fde99c4dd716dd60508fb002666acce
https://pubmed.ncbi.nlm.nih.gov/12517969
https://pubmed.ncbi.nlm.nih.gov/12517969
Publikováno v:
Brain research. 955(1-2)
Death of transplanted dopaminergic neurons is induced both during preparation of donor tissue and after intrastriatal grafting. Oxidative stress is thought to be partly responsible for this cell death. In the present study we compared the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019e573204a55566c4f568f2b1aab5f5
https://pubmed.ncbi.nlm.nih.gov/12419547
https://pubmed.ncbi.nlm.nih.gov/12419547
Publikováno v:
International immunology. 14(1)
We have previously identified a locus on mouse chromosome 15 (eae2) that regulates susceptibility to experimental autoimmune encephalomyelitis in a cross between the susceptible strain B10.RIII and the resistant strain RIIIS/J. In an effort to verify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bea751712b7d7265f74b22ec7664dba
https://pubmed.ncbi.nlm.nih.gov/11751755
https://pubmed.ncbi.nlm.nih.gov/11751755
Publikováno v:
Arthritis Research & Therapy
Introduction In a cross between two mouse strains, the susceptible B10.RIII (H-2r) and resistant RIIIS/J (H-2r) strains, a locus on mouse chromosome 5 (Eae39) was previously shown to control experimental autoimmune encephalomyelitis (EAE). Recently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4896cec9879c1788da6a0834e34b4b
http://europepmc.org/articles/PMC2688241
http://europepmc.org/articles/PMC2688241