Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jenny Apelt"'
Autor:
Jenny Apelt
Als Anton auf die Welt kommt, beschleicht die jungen Eltern schon nach wenigen Wochen das Gefühl, dass mit ihrem Sohn etwas nicht stimmt: Zunehmend plagen ihn heftige Bauchschmerzen, zudem verweigert er es immer öfter, Nahrung zu sich zu nehmen. So
Autor:
Karin Loser, Stephan Grabbe, Tobias Rothoeft, Mathias Krummen, Jenny Apelt, Stefan Beissert, Sandra Balkow, Tetsuya Higuchi, Carsten Weishaupt, Andrea Tuettenberg
Publikováno v:
Experimental Dermatology. 18:78-87
Despite as yet limited clinical effectiveness, dendritic cell (DC)-based immunotherapy remains a promising approach for the treatment of cancer, but requires further improvement in its immunostimulatory effectiveness. Potent anti-tumor immunity often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b87ae3e1a558f13c7c0068150c88cf
https://doi.org/10.1111/j.1600-0625.2008.00800.x
https://doi.org/10.1111/j.1600-0625.2008.00800.x
Autor:
Maik Voskort, Stephan Grabbe, Thomas Schwarz, Karin Loser, Jenny Apelt, Mariette Mohaupt, Sandra Balkow, Stefan Beissert
Publikováno v:
The Journal of Immunology. 179:365-371
UV radiation-induced immunosuppression contributes significantly to the development of UV-induced skin cancer by inhibiting protective immune responses. IL-10 has been shown to be a key mediator of UV-induced immunosuppression. To investigate the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eceba9e5586c5b8a5a3db2564092852
https://doi.org/10.4049/jimmunol.179.1.365
https://doi.org/10.4049/jimmunol.179.1.365
Autor:
Jenny Apelt, Ludmil Kirazov, Magdalena Gniezdzinska, Andrzej Szutowicz, Kristin Heidel, Reinhard Schliebs
Publikováno v:
Brain Research. 1122:78-85
Increased expression of interleukin (IL)-1beta has been found in Alzheimer brain, raising the question whether plaque-associated up-regulation of IL-1beta may contribute to neurodegeneration. IL-1beta is capable to induce a number of events that also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e745b837234c615610e37935fc237d
https://doi.org/10.1016/j.brainres.2006.09.014
https://doi.org/10.1016/j.brainres.2006.09.014
Publikováno v:
Gene Therapy. 12:1294-1304
Regulatory T cells are promising candidates for the modulation of inflammation and autoimmunity. To generate regulatory T cells in vitro, we have infected nadie;ve CD4⁺CD25⁻ T cells with a retrovirus encoding the transcription factor Foxp3. Foxp3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055f7f7f32cdfaa0367bf5f28c6a607c
https://doi.org/10.1038/sj.gt.3302567
https://doi.org/10.1038/sj.gt.3302567
Publikováno v:
Brain Research. 977:16-22
Cholinergic dysfunction is a consistent feature of Alzheimer's disease, and the interrelationship between beta-amyloid deposits, inflammation and early cholinergic cell loss is still not fully understood. To characterize the mechanisms by which beta-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5c707964e0a1cd8effccfc18385556
https://doi.org/10.1016/s0006-8993(03)02658-1
https://doi.org/10.1016/s0006-8993(03)02658-1
Publikováno v:
Journal of Neural Transmission. 110:77-94
Alzheimer's disease is associated with markedly impaired cerebral glucose metabolism as detected by reduced cortical desoxyglucose utilization, by altered activities of key glycolytic enzymes or by reduced densities of cortical glucose transporter su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6634d2035334f6b66f5f20772d62b435
https://doi.org/10.1007/s00702-002-0772-x
https://doi.org/10.1007/s00702-002-0772-x
Autor:
Heike Franke, Jenny Apelt, Ulrike Zeitschel, Ulrich Gärtner, Reinhard Schliebs, Volker Bigl, Albrecht Günther, Tobias Stahl, Steffen Roßner, Maike Hartlage-Rübsamen, Milena Penkowa
Publikováno v:
Glia. 41:169-179
The beta-site APP-cleaving enzyme (BACE1) is a prerequisite for the generation of β-amyloid peptides, which give rise to cerebrovascular and parenchymal β-amyloid deposits in the brain of Alzheimer's disease patients. BACE1 is neuronally expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bb01d4eba373c1ea6769079ccbd681
https://doi.org/10.1002/glia.10178
https://doi.org/10.1002/glia.10178
Publikováno v:
Neuroscience Letters. 329:111-115
To study the relationship of beta-amyloid-mediated micro- and astrogliosis and inflammation-induced proteins including intercellular adhesion molecule (ICAM-1), brain tissue from transgenic Tg2576 mice expressing the Swedish mutation of the human amy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d544cbed887841f03fe5498fe84dfec4
https://doi.org/10.1016/s0304-3940(02)00589-x
https://doi.org/10.1016/s0304-3940(02)00589-x
Publikováno v:
Bulletin of Experimental Biology and Medicine. 134:236-240
We studied properties of cloned BACE mRNA (beta-site of the enzyme cleaving amyloid precursor protein) and evaluated the possibility of using this clone for identification and/or prediction of neurodegenerative disorders associated with cholinergic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b633f4408fa41149f30202367b005a61
https://doi.org/10.1023/a:1021564231603
https://doi.org/10.1023/a:1021564231603