Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jenny A. Rudnick"'
Autor:
Christian Tomaszewski, William B. Jones, Mehrdad Mobasher, James W. Janc, Richard A. Miller, Jorge Robles, Miriam L Cameron, Gerard J. Criner, Shenshen Hu, Stephen Willingham, Pramod Guru, Long Kwei, Philippe R. Bauer, Michael F. Waters, Suresh Mahabhashyam, Haider Mashhedi, Julián Olalla Sierra, Jenny A. Rudnick, J. Scott Overcash
Robust polyclonal humoral immune responses have the potential to generate a diverse set of antibodies to neutralize and eliminate viruses such as SARS-CoV-2 and protect against transmission, re-infection and the evolution of variants that evade immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72828493e8eb39cba2f97205aef7219a
https://doi.org/10.1101/2021.09.13.21263406
https://doi.org/10.1101/2021.09.13.21263406
Autor:
Jenny A. Rudnick, Jayanta Debnath
Publikováno v:
Autophagy
Growing evidence demonstrates that macroautophagy/autophagy in the host stroma influences the tumor microenvironment. We have uncovered that autophagy in host stromal fibroblasts is compulsory to initiate and maintain the desmoplastic fibrotic respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b176557889d447a642e7453b958c66
https://pubmed.ncbi.nlm.nih.gov/34470579
https://pubmed.ncbi.nlm.nih.gov/34470579
Autor:
Sofía Bustamante Eguiguren, Jenny A. Rudnick, Jayanta Debnath, Hanna Starobinets, Florie A. Mar, Valerie M. Weaver, Juliet Goldsmith, Teresa Monkkonen, Srirupa Roy, James Matthew Barnes
Publikováno v:
Genes Dev
Genes & development, vol 35, iss 13-14
Genes & development, vol 35, iss 13-14
Autophagy inhibitors are currently being evaluated in clinical trials for the treatment of diverse cancers, largely due to their ability to impede tumor cell survival and metabolic adaptation. More recently, there is growing interest in whether and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2b277000262b8ebb439bc5a1c1e7b0
https://pubmed.ncbi.nlm.nih.gov/34168038
https://pubmed.ncbi.nlm.nih.gov/34168038
Autor:
Haider Mashhedi, Jenny A. Rudnick, Stephen Willingham, Suresh Mahabhashyam, Andrew Hotson, Barbara Daine-Matsuoka, William B. Jones, Craig M. Hill, Richard A. Miller, Joseph J. Buggy, Joshua Brody, Gerard J. Criner, Mehrdad Mobasher, Jessica Hsieh, Thomas U. Marron, Shenshen Hu, Emily Piccione
COVID-19 is a global pandemic that has resulted in over 800,000 deaths. Robust humoral anti-viral immune responses have the potential to generate a diverse set of neutralizing antibodies to eliminate viruses and protect against re-infection, transmis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96703dadfeb733be3e52521085d3231e
https://doi.org/10.1101/2020.09.10.20191486
https://doi.org/10.1101/2020.09.10.20191486
Autor:
Jenny A Rudnick, Lisa M Arendt, Ina Klebba, John W Hinds, Vandana Iyer, Piyush B Gupta, Stephen P Naber, Charlotte Kuperwasser
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24605 (2011)
Fibroblasts are important in orchestrating various functions necessary for maintaining normal tissue homeostasis as well as promoting malignant tumor growth. Significant evidence indicates that fibroblasts are functionally heterogeneous with respect
Externí odkaz:
https://doaj.org/article/8c770b64fc1f420da2cf9d1615a89c98
Autor:
Jaime R. Merchan, Jason J. Luke, James W. Janc, Thomas U. Marron, Kristen A. Marrone, Jeffrey A. Sosman, Craig M. Hill, Suresh Mahabhashyam, Brett G.M. Hughes, Jenny A. Rudnick, Abhishek Tripathi, Igor Puzanov, Richard K. Miller, Shenshen Hu, Mehrdad Mobasher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundMupadolimab (mupa) is a humanized FcγR binding-deficient IgG1 anti-CD73 antibody that has agonistic properties.1 CD73 is involved in production of adenosine and in cellular trafficking. Mupa reacts with the majority of circulating B cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d213e12f8945eee821bbde1c6d39819a
https://doi.org/10.1136/jitc-2021-sitc2021.701
https://doi.org/10.1136/jitc-2021-sitc2021.701
Publikováno v:
Clinicalexperimental metastasis. 29(7)
Breast cancer is a heterogeneous, multi-facto- rial disease of aberrant breast development whose etiology relies upon several microenvironmental changes within the tissue. Within the last decade, it has become widely accepted that tumor cells frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b800269eec4abd22ca58b0ffc89301f
https://pubmed.ncbi.nlm.nih.gov/22684404
https://pubmed.ncbi.nlm.nih.gov/22684404
Autor:
Lisa M. Arendt, Jenny A. Rudnick, John W Hinds, Ina Klebba, Vandana Iyer, Stephen P. Naber, Charlotte Kuperwasser, Piyush Gupta
Publikováno v:
PLoS
PLoS ONE
PLoS ONE, Vol 6, Iss 9, p e24605 (2011)
PLoS ONE
PLoS ONE, Vol 6, Iss 9, p e24605 (2011)
Fibroblasts are important in orchestrating various functions necessary for maintaining normal tissue homeostasis as well as promoting malignant tumor growth. Significant evidence indicates that fibroblasts are functionally heterogeneous with respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7cb7966b45ee8db6b95702d3e8cc7c
http://hdl.handle.net/1721.1/69165
http://hdl.handle.net/1721.1/69165
Autor:
Piyush Gupta, Charlotte Kuperwasser, Christine M. Fillmore, Patricia J. Keller, Jenny A. Rudnick, Eric S. Lander, Silvia Caballero
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(50)
Many tumors contain heterogeneous populations of cells, only some of which exhibit increased tumorigenicity and resistance to anticancer therapies. Evidence suggests that these aggressive cancer cells, often termed “cancer stem cells” or “cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feec569d2e343f3341942984b07cab67
https://pubmed.ncbi.nlm.nih.gov/21098263
https://pubmed.ncbi.nlm.nih.gov/21098263
Autor:
Ina Klebba, Stephen P. Naber, Roger A. Graham, Patricia J. Keller, Jenny A. Rudnick, Stuart J. Schnitt, Charlotte Kuperwasser, Ainsley D. Jones, Theresa A. DiMeo, Douglas M. Jefferson, Lisa M. Arendt, Hannah Leah Gilmore, Amy F Lin
Publikováno v:
Breast Cancer Research. 12
Introduction Normal and neoplastic breast tissues are comprised of heterogeneous populations of epithelial cells exhibiting various degrees of maturation and differentiation. While cultured cell lines have been derived from both normal and malignant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a634bfd1dd437c295fe7eb71ccb3b12
https://doi.org/10.1186/bcr2755
https://doi.org/10.1186/bcr2755