Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jenny A. Klein"'
Autor:
Martin H. Berryer, Matthew Tegtmeyer, Loïc Binan, Vera Valakh, Anna Nathanson, Darina Trendafilova, Ethan Crouse, Jenny A. Klein, Daniel Meyer, Olli Pietiläinen, Francesca Rapino, Samouil L. Farhi, Lee L. Rubin, Steven A. McCarroll, Ralda Nehme, Lindy E. Barrett
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106995- (2023)
Summary: Emerging evidence of species divergent features of astrocytes coupled with the relative inaccessibility of human brain tissue underscore the utility of human pluripotent stem cell (hPSC) technologies for the generation and study of human ast
Externí odkaz:
https://doaj.org/article/b6bff0cb1e46455bb881632757e1323b
Autor:
Zhen Li, Jenny A. Klein, Sanjeev Rampam, Ronni Kurzion, Natalie Baker Campbell, Yesha Patel, Tarik F. Haydar, Ella Zeldich
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The intellectual disability (ID) in Down syndrome (DS) is thought to result from a variety of developmental deficits such as alterations in neural progenitor division, neurogenesis, gliogenesis, cortical architecture, and reduced cortical volume. How
Externí odkaz:
https://doaj.org/article/67f9da21a494489798d3e6a36b394920
Autor:
Jenny A. Klein, Tarik F. Haydar
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Great strides have been made over the past 30 years in understanding the neurodevelopmental changes underlying the intellectual disability (ID) in Down syndrome (DS). Detailed studies of human tissue coupled with findings from rodent and induced plur
Externí odkaz:
https://doaj.org/article/8d38a6523bb3402bb7279b70c1d289b7
Autor:
Jenny A. Klein, Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia Shaw, Angela L. Rachubinski, Joaquin M. Espinosa, Ella Zeldich, Tarik F. Haydar
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
The intellectual disability found in people with Down syndrome is associated with numerous changes in early brain development, including the proliferation and differentiation of neural progenitor cells (NPCs) and the formation and maintenance of myel
Externí odkaz:
https://doaj.org/article/d0316aa1c81f46c48fea6d9bd65cb877
Autor:
Nadine M. Aziz, Jenny A. Klein, Morgan R. Brady, Jose Luis Olmos-Serrano, Vittorio Gallo, Tarik F. Haydar
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 11, Iss 1, Pp 1-17 (2019)
Abstract Background Down syndrome (DS), caused by the triplication of chromosome 21, results in a constellation of clinical features including changes in intellectual and motor function. Although altered neural development and function have been well
Externí odkaz:
https://doaj.org/article/d4b35132fe2e4d9a88c940a86424aa8a
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 9 (2020)
Mouse models of Down syndrome (DS) have been invaluable tools for advancing knowledge of the underlying mechanisms of intellectual disability in people with DS. The Ts(1716)65Dn (Ts65Dn) mouse is one of the most commonly used models as it recapitulat
Externí odkaz:
https://doaj.org/article/61f4148cd77046ca8aeed53a7a8176bd
Autor:
Martin H Berryer, Gizem Rizki, Anna Nathanson, Jenny A Klein, Darina Trendafilova, Sara G Susco, Daisy Lam, Angelica Messana, Kristina M Holton, Kyle W Karhohs, Beth A Cimini, Kathleen Pfaff, Anne E Carpenter, Lee L Rubin, Lindy E Barrett
Publikováno v:
eLife. 12
Resolving fundamental molecular and functional processes underlying human synaptic development is crucial for understanding normal brain function as well as dysfunction in disease. Based upon increasing evidence of species-divergent features of brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6ccde241ee5457aa50588c55a075609
https://doi.org/10.7554/elife.80168
https://doi.org/10.7554/elife.80168
Autor:
Martin H Berryer, Gizem Rizki, Anna Nathanson, Jenny A Klein, Darina Trendafilova, Sara G Susco, Daisy Lam, Angelica Messana, Kristina M Holton, Kyle W Karhohs, Beth A Cimini, Kathleen Pfaff, Anne E Carpenter, Lee L Rubin, Lindy E Barrett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008f9d606fa95833af908250dbc7cb32
https://doi.org/10.7554/elife.80168.sa2
https://doi.org/10.7554/elife.80168.sa2
Autor:
Martin H. Berryer, Matthew Tegtmeyer, Loïc Binan, Vera Valakh, Anna Nathanson, Darina Trendafilova, Ethan Crouse, Jenny A. Klein, Daniel Meyer, Olli Pietiläinen, Francesca Rapino, Samouil L. Farhi, Lee L. Rubin, Steven A. McCarroll, Ralda Nehme, Lindy E. Barrett
Astrocytes play essential roles in normal brain function, with dysfunction implicated in diverse developmental and degenerative disease processes. Emerging evidence of profound species divergent features of astrocytes coupled with the relative inacce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c7aae7bbb38b5cdbd606525b5d5512
https://doi.org/10.1101/2022.09.07.507028
https://doi.org/10.1101/2022.09.07.507028
Autor:
Jenny A. Klein, Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia Shaw, Angela L. Rachubinski, Joaquin M. Espinosa, Ella Zeldich, Tarik F. Haydar
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2022)
Frontiers in Cellular Neuroscience, Vol 15 (2022)
The intellectual disability found in people with Down syndrome is associated with numerous changes in early brain development, including the proliferation and differentiation of neural progenitor cells (NPCs) and the formation and maintenance of myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e1e167eaf3d681b4fc99f999f192a1
https://pubmed.ncbi.nlm.nih.gov/35058753
https://pubmed.ncbi.nlm.nih.gov/35058753