Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jenny, Zinke"'
Autor:
Daniel Spitzer, Maryam I. Khel, Tim Pütz, Jenny Zinke, Xiaoxiong Jia, Kathleen Sommer, Katharina Filipski, Frits Thorsen, Thomas M. Freiman, Stefan Günther, Karl H. Plate, Patrick N. Harter, Stefan Liebner, Yvonne Reiss, Mariangela Di Tacchio, Sylvaine Guérit, Kavi Devraj
Publikováno v:
Nature Protocols. 18:1510-1542
Autor:
Patrick N. Harter, Roy Thomas Daniel, Michael Schulz, Florian Klemm, Alexander Schaffer, Monika E. Hegi, Pia S. Zeiner, Roeltje R. Maas, Anna Salamero-Boix, Benelita T. Elie, Johanna A. Joyce, Robert L. Bowman, Katja Niesel, Lisa Sevenich, Marie Groth, Aylin Möckl, Jenny Zinke, Karl H. Plate, Tijna Alekseeva
Publikováno v:
Nature Cancer. 2:1086-1101
Tumor microenvironment-targeted therapies are emerging as promising treatment options for different cancer types. Tumor-associated macrophages and microglia (TAMs) represent an abundant nonmalignant cell type in brain metastases and have been propose
Autor:
Elena I. Ilina, Jenny Zinke, Joachim P. Steinbach, Christian Senft, Patrick N. Harter, Bastian Roller, Karl H. Plate, Peter Baumgarten, Oliver Bähr, Katharina Filipski, Pia S. Zeiner, Simon Bernatz, Michael W. Ronellenfitsch, Elke Hattingen, Michel Mittelbronn, Yannick Braun
Publikováno v:
Neuropathology and Applied Neurobiology. 47:379-393
Aims Changes in metabolism are known to contribute to tumour phenotypes. If and how metabolic alterations in brain tumours contribute to patient outcome is still poorly understood. Epigenetics impact metabolism and mitochondrial function. The aim of
Autor:
Daniel Spitzer, Sylvaine Guérit, Tim Puetz, Maryam I. Khel, Moritz Armbrust, Maika Dunst, Jadranka Macas, Jenny Zinke, Gayatri Devraj, Xiaoxiong Jia, Florian Croll, Kathleen Sommer, Katharina Filipski, Thomas M. Freiman, Mario Looso, Stefan Günther, Mariangela Di Tacchio, Karl-Heinz Plate, Yvonne Reiss, Stefan Liebner, Patrick N. Harter, Kavi Devraj
Publikováno v:
Acta neuropathologica. 144(2)
Blood–brain barrier (BBB) dysfunction, characterized by degradation of BBB junctional proteins and increased permeability, is a crucial pathophysiological feature of acute ischemic stroke. Dysregulation of multiple neurovascular unit (NVU) cell typ
Autor:
Karl H. Plate, Patrick N. Harter, Joachim P. Steinbach, Michael W. Ronellenfitsch, Jenny Zinke, David Capper, Katharina Filipski, Michel Mittelbronn, Marlies Wagner, Peter Baumgarten, Bastian Roller, Gilles Gasparoni, Yannick Braun, Christian Senft, Pia S. Zeiner
Publikováno v:
Acta Neuropathologica
Autor:
Tony Kaoma, Pia S. Zeiner, Simone P. Niclou, Ane Iriondo, Kea Franz, Anna Golebiewska, Anne Grote, Monika Müller-Eschner, Friedrich Feuerhake, Arnaud Muller, Elena I. Ilina, Simon Bernatz, Patrick N. Harter, Katharina Filipski, Anna-Eva Blank, C. Preusse, Michel Mittelbronn, Werner Stenzel, Peter Baumgarten, Marcel A. Verhoff, Jenny Zinke, Jörg Wischhusen, Martin L. Hansmann, Joachim P. Steinbach
Publikováno v:
Brain Pathology. 29:513-529
While the central nervous system is considered an immunoprivileged site and brain tumors display immunosuppressive features, both innate and adaptive immune responses affect glioblastoma (GBM) growth and treatment resistance. However, the impact of t
Autor:
Patrick N Harter, Jenny Zinke, Alexander Scholz, Julia Tichy, Cornelia Zachskorn, Hans M Kvasnicka, Benjamin Goeppert, Céline Delloye-Bourgeois, Elke Hattingen, Christian Senft, Joachim P Steinbach, Karl H Plate, Patrick Mehlen, Dorothea Schulte, Michel Mittelbronn
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92311 (2014)
The multifunctional molecule netrin-1 is upregulated in various malignancies and has recently been presented as a major general player in tumorigenesis leading to tumor progression and maintenance in various animal models. However, there is still a l
Externí odkaz:
https://doaj.org/article/02239f747ee44b2a98086e30e7b0add9
Autor:
Manfred Westphal, Markus Glatzel, Simon A. Joosse, Jenny Zinke, Melanie Janning, Malte Mohme, Harriet Wikman, Klaus Pantel, Julia T. Stadler, Moritz Schuette, Desiree Loreth, Volkmar Müller, Katrin Lamszus, Iwona Belczacka, Svenja Schneegans, Beate Volkmer, Andras Piffko, Marie-Laure Yaspo, Rüdiger Greinert, Jakob Matschke, Stefan W. Schneider, Sonja Loges, Patrick N. Harter, Christoffer Gebhardt
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6993, p 6993 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6993, p 6993 (2021)
Up to 40% of advance lung, melanoma and breast cancer patients suffer from brain metastases (BM) with increasing incidence. Here, we assessed whether circulating tumor cells (CTCs) in peripheral blood can serve as a disease surrogate, focusing on CD4
Autor:
Marcel H. Schulz, Tijna Alekseeva, Benelita T. Elie, A. Schaeffer, Lisa Sevenich, Johanna A. Joyce, Patrick N. Harter, Anna Salamero-Boix, Roy Thomas Daniel, Robert L. Bowman, M. Groth, Katja Niesel, Monika E. Hegi, Karl-Heinz Plate, Roeltje R. Maas, Pia S. Zeiner, Jenny Zinke, Florian Klemm
SUMMARYTumor microenvironment-targeted therapies are emerging as promising treatment options for different cancer types. Tumor-associated macrophages and microglia (TAMs) represent an abundant non-malignant cell type in brain metastases and have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1ca8bf0a49969a378491b852410bdd9
https://doi.org/10.1101/2021.06.07.447034
https://doi.org/10.1101/2021.06.07.447034
Autor:
Karl-Heinz Plate, Ann-Kathrin Hartmetz, Karl Schilling, Peter Baumgarten, Stefan Baader, David T.W. Jones, Dorothea Schulte, Stefan Liebner, Kai Doberstein, Rudi Beschorner, Jenny Zinke, Jens Schittenhelm, Paul Gutwein, Andrey Korshunov, Patrick N. Harter, Michel Mittelbronn, Stefan M. Pfister
Publikováno v:
Neuropathology and Applied Neurobiology. 41:165-179
Aims The paired box gene 8 (PAX8) plays crucial roles in organ patterning and cellular differentiation during development and tumorigenesis. Although its function is partly understood in vertebrate development, there is poor data concerning human cen