Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jenny, Zetterblad"'
Autor:
Josefine Åhsberg, Jenny Zetterblad, Sasan Zandi, Hong Qian, Jan-Ingvar Jönsson, Robert Månsson, Panagiotis Tsapogas, Mikael Sigvardsson
Publikováno v:
Journal of Biological Chemistry. 285:36275-36284
The development of lymphoid cells from bone marrow progenitors is dictated by interplay between internal cues such as transcription factors and external signals like the cytokines Flt-3 ligand and Il-7. These proteins are both of large importance for
Autor:
Panagiotis Tsapogas, Jenny Zetterblad, David Bryder, Mikael Sigvardsson, Robert Månsson, Sasan Zandi
Publikováno v:
Scopus-Elsevier
Development of B-lymphoid cells in the bone marrow is a process under strict control of a hierarchy of transcription factors. To understand the development of a B-lymphoid-restricted functional network of transcription factors, we have investigated t
Autor:
Peter Åkerblad, Mikael Sigvardsson, Barbro Basta, Jenny Zetterblad, Emma Smith, Anna Lagergren, Robert Månsson, David Bryder
Publikováno v:
Journal of Biological Chemistry. 282:14454-14462
The development of blood cells from hematopoietic stem cells in the bone marrow is dependent on communication with bone marrow stroma cells, making these cells central for the appropriate regulation of hematopoiesis. To identify transcription factors
Autor:
Amanda, Nordigården, Jenny, Zetterblad, Cecilia, Trinks, Henrik, Gréen, Pernilla, Eliasson, Pia, Druid, Kourosh, Lotfi, Lars, Rönnstrand, Thomas M, Walz, Jan-Ingvar, Jönsson
Publikováno v:
British journal of haematology. 155(2)
Recent findings have indicated that tyrosine kinase inhibitors (TKIs) targeting the ERBB receptor family display anti-leukaemic effects, despite the lack of receptor expression on human leukaemic cells. The occurrence of activating mutations in the g
Autor:
Josefine Åhsberg, Hong Qian, Panagiotis Tsapogas, Jenny Zetterblad, Robert Månsson, Sasan Zandi, Eva Welinder, Jan-Ingvar Jönsson, Mikael Sigvardsson
Publikováno v:
Blood. 118(5)
Deficiencies in the IL-7 signaling pathway result in severe disruptions of lymphoid development in adult mice. To understand more about how IL-7 deficiency impacts early lymphoid development, we have investigated lineage restriction events within the
Autor:
Frida Hansson, Anna Lagergren, Robert Månsson, Hong Qian, Mikael Sigvardsson, Sasan Zandi, David Bryder, Nils Paulsson, Jenny Zetterblad
Publikováno v:
BMC Genomics
BMC Genomics, Vol 11, Iss 1, p 108 (2010)
BMC Genomics, Vol 11, Iss 1, p 108 (2010)
Background The use of functional genomics has largely increased our understanding of cell biology and promises to help the development of systems biology needed to understand the complex order of events that regulates cellular differentiation in vivo
Publikováno v:
Blood. 116:3867-3867
Abstract 3867 The generation of B cells from multipotent hematopoietic stem cells involves activation of B cell specific and repression of alternative lineage programs. This process to a large extent is under the control of transcription factors such