Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Jenny, Mjösberg"'
Autor:
Marina García, Anna Carrasco García, Whitney Weigel, Wanda Christ, Ronaldo Lira-Junior, Lorenz Wirth, Johanna Tauriainen, Kimia Maleki, Giulia Vanoni, Antti Vaheri, Satu Mäkelä, Jukka Mustonen, Johan Nordgren, Anna Smed-Sörensen, Tomas Strandin, Jenny Mjösberg, Jonas Klingström
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012390 (2024)
Hantaviruses cause the acute zoonotic diseases hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Infected patients show strong systemic inflammation and immune cell activation. NK cells are highly activated in HFRS
Externí odkaz:
https://doaj.org/article/20bc63d9ae5a4700b41d8af98795e89a
Autor:
Egle Kvedaraite, Magda Lourda, Natalia Mouratidou, Tim Düking, Avinash Padhi, Kirsten Moll, Paulo Czarnewski, Indranil Sinha, Ioanna Xagoraris, Efthymia Kokkinou, Anastasios Damdimopoulos, Whitney Weigel, Olga Hartwig, Telma E. Santos, Tea Soini, Aline Van Acker, Nelly Rahkonen, Malin Flodström Tullberg, Emma Ringqvist, Marcus Buggert, Carl Jorns, Ulrik Lindforss, Caroline Nordenvall, Christopher T. Stamper, David Unnersjö-Jess, Mira Akber, Ruta Nadisauskaite, Jessica Jansson, Niels Vandamme, Chiara Sorini, Marijke Elise Grundeken, Helena Rolandsdotter, George Rassidakis, Eduardo J. Villablanca, Maja Ideström, Stefan Eulitz, Henrik Arnell, Jenny Mjösberg, Jan-Inge Henter, Mattias Svensson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Stromal cells support epithelial cell and immune cell homeostasis and play an important role in inflammatory bowel disease (IBD) pathogenesis. Here, we quantify the stromal response to inflammation in pediatric IBD and reveal subset-specific
Externí odkaz:
https://doaj.org/article/4dc18c7a87ab47da922abb5a03ceaf68
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity
Autor:
Isaac Dean, Colin Y. C. Lee, Zewen K. Tuong, Zhi Li, Christopher A. Tibbitt, Claire Willis, Fabrina Gaspal, Bethany C. Kennedy, Veronika Matei-Rascu, Rémi Fiancette, Caroline Nordenvall, Ulrik Lindforss, Syed Murtuza Baker, Christian Stockmann, Veronika Sexl, Scott A. Hammond, Simon J. Dovedi, Jenny Mjösberg, Matthew R. Hepworth, Gianluca Carlesso, Menna R. Clatworthy, David R. Withers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Immune cell dysfunction within the tumor microenvironment (TME) undermines the control of cancer progression. Established tumors contain phenotypically distinct, tumor-specific natural killer (NK) cells; however, the temporal dynamics, mecha
Externí odkaz:
https://doaj.org/article/27d36aa7031e441daba36d10fc106a98
Autor:
Roser Tachó-Piñot, Christopher T. Stamper, James I. King, Veronika Matei-Rascu, Erin Richardson, Zhi Li, Luke B. Roberts, John W. Bassett, Felipe Melo-Gonzalez, Rémi Fiancette, I-Hsuan Lin, Alexander Dent, Yohsuke Harada, Conor Finlay, Jenny Mjösberg, David R. Withers, Matthew R. Hepworth
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113425- (2023)
Summary: Innate lymphoid cells (ILCs) are tissue-resident effector cells with roles in tissue homeostasis, protective immunity, and inflammatory disease. Group 3 ILCs (ILC3s) are classically defined by the master transcription factor RORγt. However,
Externí odkaz:
https://doaj.org/article/035a6f626dd34570abb60d2053c54a08
Autor:
Laura M. Palma Medina, Haris Babačić, Majda Dzidic, Åsa Parke, Marina Garcia, Kimia T. Maleki, Christian Unge, Magda Lourda, Egle Kvedaraite, Puran Chen, Jagadeeswara Rao Muvva, Martin Cornillet, Johanna Emgård, Kirsten Moll, Karolinska K. I./K. COVID-19 Study Group, Jakob Michaëlsson, Malin Flodström-Tullberg, Susanna Brighenti, Marcus Buggert, Jenny Mjösberg, Karl-Johan Malmberg, Johan K. Sandberg, Sara Gredmark-Russ, Olav Rooyackers, Mattias Svensson, Benedict J. Chambers, Lars I. Eriksson, Maria Pernemalm, Niklas K. Björkström, Soo Aleman, Hans-Gustaf Ljunggren, Jonas Klingström, Kristoffer Strålin, Anna Norrby-Teglund
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background COVID-19 remains a major public health challenge, requiring the development of tools to improve diagnosis and inform therapeutic decisions. As dysregulated inflammation and coagulation responses have been implicated in the pathoph
Externí odkaz:
https://doaj.org/article/d9502f7d22f248878bad4b825dd78148
Autor:
Elin Rönnberg, Avinash Ravindran, Luca Mazzurana, Yitao Gong, Jesper Säfholm, Julie Lorent, Olga Dethlefsen, Ann-Charlotte Orre, Mamdoh Al-Ameri, Mikael Adner, Sven-Erik Dahlén, Joakim S. Dahlin, Jenny Mjösberg, Gunnar Nilsson
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Mast cells are tissue-resident cells playing major roles in homeostasis and disease conditions. Lung mast cells are particularly important in airway inflammatory diseases such as asthma. Human mast cells are classically divided into the subsets MCT a
Externí odkaz:
https://doaj.org/article/bd3bec31a2624883b61bd86e30bf60d4
Autor:
Sophia Björkander, Susanna Klevebro, Natalia Hernandez‐Pacheco, Maura Kere, Sandra Ekström, Maria Sparreman Mikus, Marianne vanHage, Anna James, Inger Kull, Anna Bergström, Jenny Mjösberg, Christopher Andrew Tibbitt, Erik Melén
Publikováno v:
Clinical and Translational Allergy, Vol 13, Iss 3, Pp n/a-n/a (2023)
Abstract Background Obese asthma is a complex phenotype and further characterization of the pathophysiology is needed. This study aimed to explore inflammation‐related plasma biomarkers in lean and overweight/obese asthmatics. Methods We elucidated
Externí odkaz:
https://doaj.org/article/5d390600b7d2449abfd314258d36c4f1
Autor:
Anna Rao, Otto Strauss, Efthymia Kokkinou, Mélanie Bruchard, Kumar P. Tripathi, Heinrich Schlums, Anna Carrasco, Luca Mazzurana, Viktoria Konya, Eduardo J. Villablanca, Niklas K. Björkström, Ulrik Lindforss, Hergen Spits, Jenny Mjösberg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Murine ILCs can modulate T cell responses in MHCII-dependent manner. Here the authors show that human ILCs process and present antigens and induce T-cell responses upon exposure to IL-1-family cytokines; along with the article by Lehmann et al, this
Externí odkaz:
https://doaj.org/article/e79201d95ac34780b172a9be7f149a45
Autor:
Anna Carrasco, Isabella Sjölander, Aline Van Acker, Andy Dernstedt, Johan Fehrm, Mattias Forsell, Danielle Friberg, Jenny Mjösberg, Anna Rao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tonsil hyperplasia is the most common cause of pediatric obstructive sleep apnea (OSA). Despite the growing knowledge in tissue immunology of tonsils, the immunopathology driving tonsil hyperplasia and OSA remains unknown. Here we used multi-parametr
Externí odkaz:
https://doaj.org/article/a14ca8cb8e5b4485b29ef756023f0119
Autor:
Andy Dernstedt, Jana Leidig, Anna Holm, Priscilla F. Kerkman, Jenny Mjösberg, Clas Ahlm, Johan Henriksson, Magnus Hultdin, Mattias N. E. Forsell
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Germinal centers (GC) are sites for extensive B cell proliferation and homeostasis is maintained by programmed cell death. The complement regulatory protein Decay Accelerating Factor (DAF) blocks complement deposition on host cells and therefore also
Externí odkaz:
https://doaj.org/article/4c9ed692004c4715905f099a68d5a531