Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jenny, Högström"'
Autor:
Marie Nilsberth, Anna Slotte, Tina Høegh, Sólveig Zophoníasdóttir, Jenny Högström, Annelie Johansson, Christina Olin-Scheller, Eva Tarander
Publikováno v:
Education in the North, Vol 28, Iss 3, Pp 44-62 (2021)
The aim of this article is to make visible Nordic lower secondary teachers’ experiences of the initial period of the COVID-19 pandemic, guided by three research questions: 1. What challenges and strategies can be identified in teachers’ descrip
Externí odkaz:
https://doaj.org/article/7aa79ed69d5d4f7d9c5e50598c22bd3e
Autor:
Kari Alitalo, Emilia A. Korhonen, Jefim Brodkin, Marianne Lähde, Sarika Heino, Suvendu Das, Jenny Högström, Elina Jokinen, Pauliina Kallio
Supplementary Figure S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22af66185e03584106c6c5f68525d24b
https://doi.org/10.1158/0008-5472.22426408.v1
https://doi.org/10.1158/0008-5472.22426408.v1
Autor:
Kari Alitalo, Emilia A. Korhonen, Jefim Brodkin, Marianne Lähde, Sarika Heino, Suvendu Das, Jenny Högström, Elina Jokinen, Pauliina Kallio
Abnormal vasculature in tumors leads to poor tissue perfusion and cytostatic drug delivery. Although drugs inducing vascular normalization, for example, angiopoietin-2 (Ang2)-blocking antibodies, have shown promising results in preclinical tumor mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81085bb06873c195d8de4fe9f11b70c1
https://doi.org/10.1158/0008-5472.c.6512332
https://doi.org/10.1158/0008-5472.c.6512332
Autor:
Zoltán Wiener, Jenny Högström, Ville Hyvönen, Arja M. Band, Pauliina Kallio, Tanja Holopainen, Olli Dufva, Caj Haglund, Olli Kruuna, Guillermo Oliver, Yinon Ben-Neriah, Kari Alitalo
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1943-1956 (2014)
Colorectal cancer (CRC) initiation and growth is often attributed to stem cells, yet little is known about the regulation of these cells. We show here that a subpopulation of Prox1-transcription-factor-expressing cells have stem cell activity in inte
Externí odkaz:
https://doaj.org/article/8235eee890f041a6b1f8671f4eebed38
Autor:
Jenny Högström, Emilia A. Korhonen, Elina Jokinen, Suvendu Das, Marianne Lähde, Jefim Brodkin, Kari Alitalo, Sarika Heino, Pauliina Kallio
Publikováno v:
Cancer Research. 80:2639-2650
Abnormal vasculature in tumors leads to poor tissue perfusion and cytostatic drug delivery. Although drugs inducing vascular normalization, for example, angiopoietin-2 (Ang2)-blocking antibodies, have shown promising results in preclinical tumor mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55baabe99f85a4981b9d42513e6b7b6
https://doi.org/10.1158/0008-5472.can-20-0497
https://doi.org/10.1158/0008-5472.can-20-0497
Autor:
Bo-Hyun Choi, Vipin Rawat, Jenny Högström, Philippa A. Burns, Kelly O. Conger, Mete Emir Ozgurses, Jaymin M. Patel, Tejas S. Mehta, Angelica Warren, Laura M. Selfors, Taru Muranen, Jonathan L. Coloff
Publikováno v:
Cell reports. 38(3)
A major challenge of targeting metabolism for cancer therapy is pathway redundancy, in which multiple sources of critical nutrients can limit the effectiveness of some metabolism-targeted therapies. Here, we analyze lineage-dependent gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5292e4d297706379c926f2891a30055
https://pubmed.ncbi.nlm.nih.gov/35045283
https://pubmed.ncbi.nlm.nih.gov/35045283
Autor:
Diego Balboa, Zoltán Wiener, Kari Alitalo, Pauliina Kallio, Veli-Matti Leppänen, Jenny Högström, Marianne Lähde, Sarika Heino
Publikováno v:
Cancer Research. 78:5820-5832
The homeobox transcription factor PROX1 is induced by high Wnt/β-catenin activity in intestinal adenomas and colorectal cancer, where it promotes tumor progression. Here we report that in LGR5+ colorectal cancer cells, PROX1 suppresses the Notch pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10640588a0748557a0c5e1144cf7b12
https://doi.org/10.1158/0008-5472.can-18-0451
https://doi.org/10.1158/0008-5472.can-18-0451
Autor:
Marianne, Lähde, Sarika, Heino, Jenny, Högström, Seppo, Kaijalainen, Andrey, Anisimov, Dustin, Flanagan, Pauliina, Kallio, Veli-Matti, Leppänen, Ari, Ristimäki, Olli, Ritvos, Katherine, Wu, Tuomas, Tammela, Michael, Hodder, Owen J, Sansom, Kari, Alitalo
Publikováno v:
Gastroenterology. 160(1)
Mutations in the APC gene and other genes in the Wnt signaling pathway contribute to development of colorectal carcinomas. R-spondins (RSPOs) are secreted proteins that amplify Wnt signaling in intestinal stem cells. Alterations in RSPO genes have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::371e6f7f66460c761daff918593b3f25
https://pubmed.ncbi.nlm.nih.gov/32941878
https://pubmed.ncbi.nlm.nih.gov/32941878
Autor:
Marianne Lähde, Sarika Heino, Jenny Högström, Veli-Matti Leppänen, Seppo Kaijalainen, Olli Ritvos, Owen Sansom, Kari Alitalo
Publikováno v:
Cancer Research. 79:LB-094
Colorectal cancers (CRCs) most commonly develop from adenomas harboring a mutant APC gene that leads to aberrant activation of the canonical Wnt/ß-catenin pathway. One of the mechanisms of adenoma progression involves the PROX1 transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909fc35d725e559df3ce96c3d3dba6ab
https://doi.org/10.1158/1538-7445.am2019-lb-094
https://doi.org/10.1158/1538-7445.am2019-lb-094
Autor:
Pauliina Kallio, Suvendu Das, Marianne Lähde, Jenny Högström, Sarika Heino, Kari Alitalo, Elina Jokinen
Publikováno v:
Cancer Research. 78:861-861
Almost 50 % of all cancer patients receive radiation therapy during their treatment, yet several tumor types show radiation therapy resistance that compromises treatment efficacy. Many radiation sensitizers have been tested for improvement of the out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::770338b707127e952d4cdaa1e401a1be
https://doi.org/10.1158/1538-7445.am2018-861
https://doi.org/10.1158/1538-7445.am2018-861