Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jennifer Y. Waugh"'
Autor:
Linda Cassiano, Jennifer Y. Waugh, Melissa Petersen, Craig A. Smith, Brian M. Macduff, Wenie S. Din, Dorothy L. Parshley, Raymond G. Goodwin, Wilson Chin, Terri Davis-Smith, Marek Kubin, Richard J. Armitage, Luis Borges, Giorgio Trinchieri
Publikováno v:
European Journal of Immunology. 29:3466-3477
Using the monoclonal antibody C1.7, which recognizes a signaling, membrane-bound molecule on human NK and a proportion of CD8(+) T cells, we cloned a novel molecule we refer to as NK cell activation-inducing ligand (NAIL). It is a 365-amino acid prot
Autor:
Thomas S. Griffith, Charles T. Rauch, Pam J. Smolak, Jennifer Y. Waugh, Norman Boiani, David H. Lynch, Craig A. Smith, Raymond G. Goodwin, Marek Z. Kubin
Publikováno v:
The Journal of Immunology. 162:2597-2605
mAbs were generated against the extracellular domain of the four known TNF-related apoptosis-inducing ligand (TRAIL) receptors and tested on a panel of human melanoma cell lines. The specificity of the mAb permitted a precise evaluation of the TRAIL
Autor:
Craig A. Smith, William C. Dougall, Pamela J. Smolak, Mariapia A. Degli-Esposti, Raymond G. Goodwin, Jennifer Y. Waugh
Publikováno v:
Immunity. 7(6):813-820
A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has been cloned and characterized. TRAIL-R4 encodes a 386–amino acid protein with an extracellular domain showing 58%–70% identity to those of TRAIL-R1, TRAIL-R2, and TRAIL-R3. The
Autor:
Mariapia A. Degli-Esposti, Charles Rauch, Pam J. Smolak, Kenneth A. Schooley, Raymond G. Goodwin, Henning Walczak, Richard S. Johnson, Mary Gerhart, Martin Timour, Jennifer Y. Waugh, Craig A. Smith, Norman Boiani
Publikováno v:
The EMBO Journal. 16:5386-5397
TRAIL is a member of the tumor necrosis factor (TNF) family of cytokines and induces apoptosis in a wide variety of cells. Based on homology searching of a private database, a receptor for TRAIL (DR4 or TRAIL-R1) was recently identified. Here we repo
Autor:
Chang Pin Huang, Jennifer Y. Waugh, Raymond G. Goodwin, Craig A. Smith, Robert F. DuBose, Henning Walczak, Pamela J. Smolak, Mariapia A. Degli-Esposti
Publikováno v:
The Journal of Experimental Medicine
TRAIL-R3, a new member of the TRAIL receptor family, has been cloned and characterized. TRAIL-R3 encodes a 299 amino acid protein with 58 and 54% overall identity to TRAIL-R1 and -R2, respectively. Transient expression and quantitative binding studie