Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jennifer Y. Tanir"'
Autor:
Lauren Heine, Pamela J. Spencer, Cathy Rudisill, Rachel V. Simon, Joel Tickner, Molly Jacobs, Peter Fantke, Jennifer Y. Tanir, Sally Edwards, Xiaoying Zhou, Tim Malloy
Publikováno v:
Tickner, J, Simon, R, Jacobs, M, Rudisill, C, Tanir, J, Heine, L, Spencer, P, Fantke, P, Malloy, T F, Edwards, S & Zhou, X 2019, ' Lessons from the 2018 International Symposium on Alternatives Assessment: Advances and reflections on practice and ongoing needs to build the field ', Environmental Toxicology and Chemistry, vol. 15, no. 6, pp. 909-916 . https://doi.org/10.1002/ieam.4213
Alternatives assessment is gaining traction as a systematic method to support the informed substitution of chemicals of concern. The 2nd International Symposium on Alternatives Assessment, on 1-2 November 2018, convened nearly 150 professionals from
Publikováno v:
Clean Technologies and Environmental Policy. 21:395-411
Chemical and product manufacturers, spurred by recent environmental and sustainability initiatives, are seeking to embrace alternatives assessment to identify suitable alternative chemicals that are safer and more sustainable for use in consumer and/
Autor:
Ben Gilby, Maik Schuler, Jennifer Y. Tanir, Shambhu K Roy, Kiyohiro Hashimoto, James Whitwell, Azeddine Elhajouji, Christopher S Farabaugh, David P. Lovell, Yan Li, Mick Fellow
A database of the micronuclei counts was built up for historical negative control data from human lymphocyte in vitro micronuclei tests (MnVit) carried out in 8 laboratories with experience of the method. The mean incidence of micronucleated cells (m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3065302df8498969d5b3700a7b28928e
https://openaccess.sgul.ac.uk/id/eprint/110519/1/1-s2.0-S1383571818301578-main.pdf
https://openaccess.sgul.ac.uk/id/eprint/110519/1/1-s2.0-S1383571818301578-main.pdf
Autor:
Jennifer Y. Tanir, Elisabeth Lorge, Mick D. Fellows, Véronique Thybaud, Masamitsu Honma, M.R. O'Donovan, B. Bhaskar Gollapudi, Marilyn J. Aardema, A. Kohara, Michael J. Armstrong, Sheila M. Galloway, Julie Clements, Martha M. Moore
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 809:1-15
Good cell culture practice and characterization of the cell lines used are of critical importance in in vitro genotoxicity testing. The objective of this initiative was to make continuously available stocks of the characterized isolates of the most f
Autor:
Emiel Rorije, David Kirkland, Jennifer Y. Tanir, Kerry L. Dearfield, Mirjam Luijten, Albert P. Li, Rosalie K. Elespuru, Errol Zeiger, Carole L. Yauk, Véronique Thybaud, Lynn H. Pottenger, Francesco Marchetti, George R. Douglas, Jeffrey C. Bemis, Jan van Benthem, George E. Johnson, B. Bhaskar Gollapudi, Matthew J. LeBaron, R. Daniel Benz
Publikováno v:
Environmental and Molecular Mutagenesis. 58:264-283
For several decades, regulatory testing schemes for genetic damage have been standardized where the tests being utilized examined mutations and structural and numerical chromosomal damage. This has served the genetic toxicity community well when most
Autor:
Azeddine Elhajouji, Zhanna Sobol, Véronique Thybaud, Jennifer Y. Tanir, Peter Kasper, Anthony M. Lynch, Andreas Sutter, Melanie Guérard, Mick D. Fellows
Publikováno v:
Mutagenesis. 31:375-384
The ICH S6(R1) recommendations on safety evaluation of biotherapeutics have led to uncertainty in determining what would constitute a cause for concern that would require genotoxicity testing. A Health and Environmental Sciences Institute's Genetic T
Autor:
Ann T. Doherty, Leon F. Stankowski, Jennifer Y. Tanir, Julia Kenny, Tao Chen, Brinda Mahadevan, Marilyn J. Aardema, Martha M. Moore, Gladys Ouedraogo, Christopher S Farabaugh, Shareen H. Doak, Mugimane G. Manjanatha, Stefan Pfuhler, Rosalie K. Elespuru
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 164(2)
Nanomaterials (NMs) present unique challenges in safety evaluation. An international working group, the Genetic Toxicology Technical Committee of the International Life Sciences Institute's Health and Environmental Sciences Institute, has addressed i
Autor:
Michelle R. Embry, Dana Sargent, Jennifer Y. Tanir, Nina E. Heard, Nancy G. Doerrer, Ronald N. Hines, Anna Lowit, James H. Sherman, Richard D. Phillips, John E. Doe, Deborah R. Lander, Timothy P. Pastoor
Publikováno v:
Critical Reviews in Toxicology
The HESI-coordinated RISK21 roadmap and matrix are tools that provide a transparent method to compare exposure and toxicity information and assess whether additional refinement is required to obtain the necessary precision level for a decision regard
Publikováno v:
Vaccine. 33(13):1507-1514
Questions have been recently raised regarding the safety of vaccine adjuvants, particularly in relation to autoimmunity or autoimmune disease(s)/disorder(s) (AID). The International Life Sciences Institute (ILSI) Health and Environmental Sciences Ins
Autor:
Jennifer Y. Tanir, B. Bhaskar Gollapudi, Darrell R. Boverhof, Seiichi Ishida, Jan van Benthem, Masamitsu Honma, James H. Kim, Raymond R. Tice, Scott S. Auerbach, Andrea L. Kasinski, William Slikker, Laura Custer, Véronique Thybaud, Paul D. White, Errol Zeiger, Igor P. Pogribny, Kristine L. Witt, Leon F. Stankowski, Peter C. Dedon, Marilyn J. Aardema, Jennifer Marlowe, Mugimane G. Manjanatha, Stefan Pfuhler
Publikováno v:
Environmental and Molecular Mutagenesis. 56:277-285
Genetic toxicity tests currently used to identify and characterize potential human mutagens and carcinogens rely on measurements of primary DNA damage, gene mutation, and chromosome damage in vitro and in rodents. The International Life Sciences Inst